在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SH2D1B Antibody, FITC conjugated

  • 中文名稱:
    SH2D1B兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA021210LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SH2D1B Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    SH2D1B antibody; EAT2 antibody; SH2 domain-containing protein 1B antibody; EWS/FLI1-activated transcript 2 antibody; EAT-2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human SH2 domain-containing protein 1B protein (1-77AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as CD84, SLAMF1, LY9 and CD244. In SLAM signaling seems to cooperate with SH2D1A/SAP. Plays a role in regulation of effector functions of natural killer (NK) cells by controlling signal transduction through CD244/2B4 without effecting its tyrosine phosphorylation; downstream signaling involves PLCG1 and ERK activation. Activation of SLAMF7-mediated NK cell function does not effect receptor tyrosine phosphorylation but distal signaling. In the context of NK cell-mediated cytotoxicity does not enhance conjugate formation with target cells but stimulates polarization of the microtubule-organizing center and cytotoxic granules toward the NK cell synapse. Negatively regulates CD40-induced cytokine production in dendritic cells downstream of SLAM family receptors probably by inducing activation of the PI3K pathway to inhibit p38 MAPK and JNK activation.
  • 基因功能參考文獻:
    1. When compared with SAP, the other single SH2 domain protein in human, EAT2 shows similar binding energies to unphosphorylated ligands. This is inconsistent to the previous data showing low affinity of EAT2 toward unphosphorylated peptides compared to SAP which shows high affinity PMID: 27586300
    2. Data indicate that Ewing's sarcoma-associated transcript-2 (EAT-2) over-expression increased the anti-tumor activity of NK cells against K562 tumor cell. targets. PMID: 24374770
    3. EAT-2 mediates its effects in natural killer cells by linking SLAM family receptors to phospholipase Cgamma, calcium fluxes, and Erk kinase. PMID: 24687958
  • 數據庫鏈接:

    HGNC: 30416

    OMIM: 608510

    KEGG: hsa:117157

    STRING: 9606.ENSP00000356906

    UniGene: Hs.350581



主站蜘蛛池模板: 日韩午夜理论免费tv影院| 噜噜色综合噜噜色噜噜色| 久久不见久久见免费影院www日本 99久久无色码中文字幕 | 亚洲视频高清不卡在线观看| 国产成人无码短视频| 99久久久无码国产精品6| 国产乱了真实在线观看| 精品一区二区三区国产在线观看| 国产在线不卡精品网站| 成人免费一区二区三区| 亚洲精品无码av专区最新| 国产经典三级av在线播放| av片在线播放| 韩国美女视频黄是免费| 亚洲久热中文字幕在线| 精品精品国产理论在线观看| 国产亚洲欧美在线专区| 无码无遮挡又大又爽又黄的视频| 免费观看在线a毛片| 国精品午夜福利视频| 久久97超碰色中文字幕蜜芽| 亚州av综合色区无码一区| 日本强伦片中文字幕免费看| 午夜内射中出视频| 亚洲人ⅴsaⅴ国产精品| 久久综合88熟人妻| 国产成人精品视频网站| 久久青青草免费线频观| 丰满人妻熟妇乱又伦精品| 亚洲日韩片无码中文字幕| 久久精品国产久精国产爱| 亚洲日韩精品无码专区| 久久亚洲精品成人av无码网站| 免费人成网站在线观看视频| 亚洲伊人成综合网| 欧美成人精品手机在线| 九色综合九色综合色鬼| 男人添女人下部高潮全视频| 无码一区二区三区| 男人的天堂av社区在线| 国产又爽又大又黄a片|