在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SH2D1B Antibody

  • 中文名稱:
    SH2D1B兔多克隆抗體
  • 貨號:
    CSB-PA021210GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    SH2D1B antibody; EAT2 antibody; SH2 domain-containing protein 1B antibody; EWS/FLI1-activated transcript 2 antibody; EAT-2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SH2D1B
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as CD84, SLAMF1, LY9 and CD244. In SLAM signaling seems to cooperate with SH2D1A/SAP. Plays a role in regulation of effector functions of natural killer (NK) cells by controlling signal transduction through CD244/2B4 without effecting its tyrosine phosphorylation; downstream signaling involves PLCG1 and ERK activation. Activation of SLAMF7-mediated NK cell function does not effect receptor tyrosine phosphorylation but distal signaling. In the context of NK cell-mediated cytotoxicity does not enhance conjugate formation with target cells but stimulates polarization of the microtubule-organizing center and cytotoxic granules toward the NK cell synapse. Negatively regulates CD40-induced cytokine production in dendritic cells downstream of SLAM family receptors probably by inducing activation of the PI3K pathway to inhibit p38 MAPK and JNK activation.
  • 基因功能參考文獻:
    1. When compared with SAP, the other single SH2 domain protein in human, EAT2 shows similar binding energies to unphosphorylated ligands. This is inconsistent to the previous data showing low affinity of EAT2 toward unphosphorylated peptides compared to SAP which shows high affinity PMID: 27586300
    2. Data indicate that Ewing's sarcoma-associated transcript-2 (EAT-2) over-expression increased the anti-tumor activity of NK cells against K562 tumor cell. targets. PMID: 24374770
    3. EAT-2 mediates its effects in natural killer cells by linking SLAM family receptors to phospholipase Cgamma, calcium fluxes, and Erk kinase. PMID: 24687958
  • 數據庫鏈接:

    HGNC: 30416

    OMIM: 608510

    KEGG: hsa:117157

    STRING: 9606.ENSP00000356906

    UniGene: Hs.350581



主站蜘蛛池模板: a在线视频v视频| 日本护士xxxxhd少妇| 动漫精品中文无码卡通动漫 | 欧美亚洲国产一区二区三区| 少妇把腿扒开让我爽爽视频| 欧美成人h亚洲综合在线观看| 中文字幕一区日韩精品| 国产偷v国产偷v亚洲高清| 美女露全乳无遮掩视频| 国产xxxx做受视频| 少妇大胆瓣开下部自慰| 99国产精品久久99久久久| 又黄又爽又猛的视频免费| 无码成人片在线播放| 欧洲免费一区二区三区视频| 国产精品成人一区无码| 无码人妻丰满熟妇精品区| 欧美成 人影片 aⅴ免费观看| 久久99精品国产99久久6男男| 国产麻豆一精品一av一免费| 欧美性开放情侣网站| 亚洲精品一区二区玖玖爱| 色老头精品午夜福利视频| 国产成人久久777777| 最新精品国偷自产在线| 成人h动漫无码网站久久| 国产精品人妻在线观看| 99热这里只有精品免费播放| 国产精品无码av天天爽| 中文字幕av无码人妻| 无码午夜人妻一区二区三区不卡视频| 午夜成人亚洲理伦片在线观看| 特黄做受又粗又长又大又硬| 成人国产一区二区精品小说| 国产中文字字幕乱码无限| 日本日本乱码伦视频在线观看| 日本高清www无色夜在线视频| 久久精品久久精品久久39| 樱花影院电视剧免费| 国产成人片无码免费视频软件 | 99久久精品国产一区二区|