在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human SH2 domain-containing protein 1B (SH2D1B)

  • 中文名稱:
    人SH2D1B重組蛋白
  • 貨號:
    CSB-YP021210HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SH2D1B重組蛋白
  • 貨號:
    CSB-EP021210HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SH2D1B重組蛋白
  • 貨號:
    CSB-EP021210HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SH2D1B重組蛋白
  • 貨號:
    CSB-BP021210HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SH2D1B重組蛋白
  • 貨號:
    CSB-MP021210HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    SH2D1B; EAT2; SH2 domain-containing protein 1B; EWS/FLI1-activated transcript 2; EAT-2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-132
  • 氨基酸序列
    MDLPYYHGRL TKQDCETLLL KEGVDGNFLL RDSESIPGVL CLCVSFKNIV YTYRIFREKH GYYRIQTAEG SPKQVFPSLK ELISKFEKPN QGMVVHLLKP IKRTSPSLRW RGLKLELETF VNSNSDYVDV LP
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as CD84, SLAMF1, LY9 and CD244. In SLAM signaling seems to cooperate with SH2D1A/SAP. Plays a role in regulation of effector functions of natural killer (NK) cells by controlling signal transduction through CD244/2B4 without effecting its tyrosine phosphorylation; downstream signaling involves PLCG1 and ERK activation. Activation of SLAMF7-mediated NK cell function does not effect receptor tyrosine phosphorylation but distal signaling. In the context of NK cell-mediated cytotoxicity does not enhance conjugate formation with target cells but stimulates polarization of the microtubule-organizing center and cytotoxic granules toward the NK cell synapse. Negatively regulates CD40-induced cytokine production in dendritic cells downstream of SLAM family receptors probably by inducing activation of the PI3K pathway to inhibit p38 MAPK and JNK activation.
  • 基因功能參考文獻:
    1. When compared with SAP, the other single SH2 domain protein in human, EAT2 shows similar binding energies to unphosphorylated ligands. This is inconsistent to the previous data showing low affinity of EAT2 toward unphosphorylated peptides compared to SAP which shows high affinity PMID: 27586300
    2. Data indicate that Ewing's sarcoma-associated transcript-2 (EAT-2) over-expression increased the anti-tumor activity of NK cells against K562 tumor cell. targets. PMID: 24374770
    3. EAT-2 mediates its effects in natural killer cells by linking SLAM family receptors to phospholipase Cgamma, calcium fluxes, and Erk kinase. PMID: 24687958
  • 數據庫鏈接:

    HGNC: 30416

    OMIM: 608510

    KEGG: hsa:117157

    STRING: 9606.ENSP00000356906

    UniGene: Hs.350581



主站蜘蛛池模板: 无码骚夜夜精品| 无码av一区二区大桥久未| 国产精品69人妻无码久久| 日本一卡二卡3卡四卡网站精品 | 亚洲国产精品无码专区成人 | 亚洲国精产品一二二线| 成 人 亚洲 综合天堂| 在线永久无码不卡av| 人人妻人人澡av| 无码高潮少妇毛多水多水免费 | 99热亚洲色精品国产88| 久久996re热这里有精品| 欧美成人片一区二区三区| 精品国产不卡一区二区三区| 精品国产乱码久久久久久乱码| 国产精品线路一线路二| 日韩夜夜高潮夜夜爽无码| 久久久久久久久免费看无码| 色欲av久久综合人妻无码| 久久久久久久久久久综合日本| 亚洲 成人 无码 在线观看 | 欧美成人看片一区二三区图文| 无码精品久久久天天影视| 日本不卡一区二区三区| 人妻中文字幕av无码专区| 97在线成人国产在线视频| 蜜臀av 国内精品久久久| 国产白嫩美女在线观看| 9九色桋品熟女内射| 精品国产v无码大片在线观看| 大黑人交xxxx18视频| 亚洲精品国产品国语在线观看| 偷窥 亚洲 另类 图片 熟女 | 人人妻人人澡av| 午夜时刻免费入口| 国产av亚洲aⅴ一区二区 | 久青草无码视频在线观看| 动漫精品专区一区二区三区| 国产成人av一区二区在线观看| 日韩一本之道一区中文字幕| 日韩内射激情视频在线播放免费|