在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human SH2 domain-containing protein 1B (SH2D1B)

  • 中文名稱:
    人SH2D1B重組蛋白
  • 貨號:
    CSB-YP021210HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SH2D1B重組蛋白
  • 貨號:
    CSB-EP021210HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SH2D1B重組蛋白
  • 貨號:
    CSB-EP021210HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SH2D1B重組蛋白
  • 貨號:
    CSB-BP021210HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SH2D1B重組蛋白
  • 貨號:
    CSB-MP021210HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    SH2D1B; EAT2; SH2 domain-containing protein 1B; EWS/FLI1-activated transcript 2; EAT-2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-132
  • 氨基酸序列
    MDLPYYHGRL TKQDCETLLL KEGVDGNFLL RDSESIPGVL CLCVSFKNIV YTYRIFREKH GYYRIQTAEG SPKQVFPSLK ELISKFEKPN QGMVVHLLKP IKRTSPSLRW RGLKLELETF VNSNSDYVDV LP
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as CD84, SLAMF1, LY9 and CD244. In SLAM signaling seems to cooperate with SH2D1A/SAP. Plays a role in regulation of effector functions of natural killer (NK) cells by controlling signal transduction through CD244/2B4 without effecting its tyrosine phosphorylation; downstream signaling involves PLCG1 and ERK activation. Activation of SLAMF7-mediated NK cell function does not effect receptor tyrosine phosphorylation but distal signaling. In the context of NK cell-mediated cytotoxicity does not enhance conjugate formation with target cells but stimulates polarization of the microtubule-organizing center and cytotoxic granules toward the NK cell synapse. Negatively regulates CD40-induced cytokine production in dendritic cells downstream of SLAM family receptors probably by inducing activation of the PI3K pathway to inhibit p38 MAPK and JNK activation.
  • 基因功能參考文獻:
    1. When compared with SAP, the other single SH2 domain protein in human, EAT2 shows similar binding energies to unphosphorylated ligands. This is inconsistent to the previous data showing low affinity of EAT2 toward unphosphorylated peptides compared to SAP which shows high affinity PMID: 27586300
    2. Data indicate that Ewing's sarcoma-associated transcript-2 (EAT-2) over-expression increased the anti-tumor activity of NK cells against K562 tumor cell. targets. PMID: 24374770
    3. EAT-2 mediates its effects in natural killer cells by linking SLAM family receptors to phospholipase Cgamma, calcium fluxes, and Erk kinase. PMID: 24687958
  • 數據庫鏈接:

    HGNC: 30416

    OMIM: 608510

    KEGG: hsa:117157

    STRING: 9606.ENSP00000356906

    UniGene: Hs.350581



主站蜘蛛池模板: 亚洲另类欧美小说图片区| 亚洲日韩日本中文在线| 日韩人妻ol丝袜av一二区| 中文字幕av伊人av无码av| 亚洲日韩va无码中文字幕| 无码丰满熟妇| 欧美顶级少妇作爱| 亚洲va中文字幕无码毛片| 亚洲精品久久久久中文字幕二区| 很黄很黄的曰批视频| 东京热大乱系列无码| 亚洲国产一成人久久精品 | 国产成人精品亚洲日本在线观看| 女人被爽到高潮视频免费国产 | 九色porny丨自拍视频| 欧美天天拍在线视频| 无码精品人妻一区二区三区98| 国产jjizz女人多水| 日韩卡二卡三卡四卡永久入口 | 亚洲精品无码永久中文字幕| 欧美性猛交xxxxx按摩欧美| 国产一区二区三区在线视頻 | 国产精品成人va在线观看| 欧美亚洲国产一区二区三区| 亚洲一区二区三区播放| 日韩精品久久久久久免费| 亚洲精品嫩草研究院久久| 熟女人妻av完整一区二区三区| 亚洲女人色综合小说| 少妇人妻大乳在线视频不卡| 一卡二卡3卡4卡视频免费播放| 欧洲av成本人在线观看免费| 小说区亚洲综合第1页| 人人狠狠综合久久88成人| 77777五月色婷婷丁香视频| 免费高清av一区二区三区| 国产成人无码a区在线| 天堂网www天堂在线资源| 久久精品国产第一区二区三区| 亚洲aⅴ永久无码一区二区三区| 国产sm调教折磨视频失禁|