在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SH2D1B Antibody

  • 中文名稱:
    SH2D1B兔多克隆抗體
  • 貨號:
    CSB-PA693732
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using SH2D1B antibody.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) SH2D1B Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human SH2D1B.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:50-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as CD84, SLAMF1, LY9 and CD244. In SLAM signaling seems to cooperate with SH2D1A/SAP. Plays a role in regulation of effector functions of natural killer (NK) cells by controlling signal transduction through CD244/2B4 without effecting its tyrosine phosphorylation; downstream signaling involves PLCG1 and ERK activation. Activation of SLAMF7-mediated NK cell function does not effect receptor tyrosine phosphorylation but distal signaling. In the context of NK cell-mediated cytotoxicity does not enhance conjugate formation with target cells but stimulates polarization of the microtubule-organizing center and cytotoxic granules toward the NK cell synapse. Negatively regulates CD40-induced cytokine production in dendritic cells downstream of SLAM family receptors probably by inducing activation of the PI3K pathway to inhibit p38 MAPK and JNK activation.
  • 基因功能參考文獻:
    1. When compared with SAP, the other single SH2 domain protein in human, EAT2 shows similar binding energies to unphosphorylated ligands. This is inconsistent to the previous data showing low affinity of EAT2 toward unphosphorylated peptides compared to SAP which shows high affinity PMID: 27586300
    2. Data indicate that Ewing's sarcoma-associated transcript-2 (EAT-2) over-expression increased the anti-tumor activity of NK cells against K562 tumor cell. targets. PMID: 24374770
    3. EAT-2 mediates its effects in natural killer cells by linking SLAM family receptors to phospholipase Cgamma, calcium fluxes, and Erk kinase. PMID: 24687958
  • 數(shù)據(jù)庫鏈接:

    HGNC: 30416

    OMIM: 608510

    KEGG: hsa:117157

    STRING: 9606.ENSP00000356906

    UniGene: Hs.350581



主站蜘蛛池模板: 日本乱理伦片在线观看中文| 日韩精品中文字幕无码一区| 国产免费一卡二卡三卡四卡| 奇米777狠狠色噜噜狠狠狠| 国产三级在线观看播放视频| 中文人妻熟女乱又乱精品| 国产精品国产三级国产aⅴ下载| av中文无码乱人伦在线观看| 好爽好湿好硬好大免费视频| 色欲色香天天天综合vvv| 少妇无码av无码专线区大牛影院| 精品国产亚洲一区二区三区在线观看 | 亚洲国产成人精品无码一区二区 | 特级毛片内射www无码| 国产无套内射普通话对白| 麻豆国产在线精品国偷产拍| 国产精品无需播放器在线观看| 免费人成在线观看视频高潮| 久久天天躁狠狠躁夜夜av| 免费人成在线观看网站品善网| 久久天天躁夜夜躁狠狠85| 精品 在线 视频 亚洲| 国产suv精品一区| 18禁无遮挡无码网站免费| 国内少妇偷人精品视频| 欧美丰满老熟妇aaaa片| 国模裸体无码xxxx视频| 亚洲欧洲自拍拍偷精品网 | 毛片免费视频在线观看| 日本熟妇人妻xxxxx| 夜晚被公侵犯的人妻深田字幕 | 午夜福利无码不卡在线观看| 啦啦啦中文在线观看日本| 久久精品成人免费国产片小草| 国产精品久久久久影院亚瑟| 成人免费看片又大又黄| 丁香五月婷激情综合第九色| 日本xxxx18野外无毒不卡| 久久妇女高潮喷水多| 樱花草在线社区www中国中文| 久久国产精品老女人|