在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SH2D1B Antibody

  • 中文名稱:
    SH2D1B兔多克隆抗體
  • 貨號(hào):
    CSB-PA006883
  • 規(guī)格:
    ¥1090
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    SH2D1B antibody; EAT2 antibody; SH2 domain-containing protein 1B antibody; EWS/FLI1-activated transcript 2 antibody; EAT-2 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human EAT-2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as CD84, SLAMF1, LY9 and CD244. In SLAM signaling seems to cooperate with SH2D1A/SAP. Plays a role in regulation of effector functions of natural killer (NK) cells by controlling signal transduction through CD244/2B4 without effecting its tyrosine phosphorylation; downstream signaling involves PLCG1 and ERK activation. Activation of SLAMF7-mediated NK cell function does not effect receptor tyrosine phosphorylation but distal signaling. In the context of NK cell-mediated cytotoxicity does not enhance conjugate formation with target cells but stimulates polarization of the microtubule-organizing center and cytotoxic granules toward the NK cell synapse. Negatively regulates CD40-induced cytokine production in dendritic cells downstream of SLAM family receptors probably by inducing activation of the PI3K pathway to inhibit p38 MAPK and JNK activation.
  • 基因功能參考文獻(xiàn):
    1. When compared with SAP, the other single SH2 domain protein in human, EAT2 shows similar binding energies to unphosphorylated ligands. This is inconsistent to the previous data showing low affinity of EAT2 toward unphosphorylated peptides compared to SAP which shows high affinity PMID: 27586300
    2. Data indicate that Ewing's sarcoma-associated transcript-2 (EAT-2) over-expression increased the anti-tumor activity of NK cells against K562 tumor cell. targets. PMID: 24374770
    3. EAT-2 mediates its effects in natural killer cells by linking SLAM family receptors to phospholipase Cgamma, calcium fluxes, and Erk kinase. PMID: 24687958
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 30416

    OMIM: 608510

    KEGG: hsa:117157

    STRING: 9606.ENSP00000356906

    UniGene: Hs.350581



主站蜘蛛池模板: 成人女人黄网站免费视频| 国产特级毛片aaaaaaa高清| 亚洲成a人片在线观看无码 | 亚洲精品国产一区二区三| 欧美高清大屁股xxxxx| 亚洲一区二区三区乱码在线欧洲 | 免费无码又爽又刺激高潮的动态图| 久久青草成人综合网站| 人妻无码精品久久亚瑟影视| 无卡无码无免费毛片| 国产精品久久..4399| 国产一区二区三区在线蜜桃| 2021国产精品国产精华| 国产乱子伦60女人的皮视频| 日本熟妇浓毛hdsex| 强辱丰满人妻hd中文字幕| 国内精品美女a∨在线播放| 18禁美女裸体无遮挡免费观看国产| 欧美精品无码久久久久久| 精品人妻系列无码人妻漫画| 天堂国产一区二区三区| 无码东京热一区二区三区| 亚洲bbw性色大片| 曰曰摸夜夜添夜夜添高潮出水| 免费观看全黄做爰的视频| 欧美506070老妇乱子伦| 成人亚洲精品777777| 东京热无码av男人的天堂| 久久无码国产专区精品| 天天摸夜夜添狠狠添高潮出水 | 亚洲精品毛片一区二区三区| 午夜阳光精品一区二区三区| 成人爱做日本视频免费| 女被啪到深处喷水gif动态图| 黑人大战日本人妻嗷嗷叫不卡视频| 大胸美女被吃奶爽死视频| 亚洲国产日韩精品一区二区三区| 丝袜自慰一区二区三区| 国产中的精品av一区二区| 亚洲精品国偷拍自产在线观看蜜桃| 亚洲熟妇色自偷自拍另类|