在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Vacuolar protein sorting-associated protein 11 homolog (VPS11), partial

Recombinant Human Vacuolar protein sorting-associated protein 11 homolog (VPS11), partial

  • 中文名稱：
    人VPS11重組蛋白
  • 貨號：
    CSB-YP887959HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人VPS11重組蛋白
  • 貨號：
    CSB-EP887959HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人VPS11重組蛋白
  • 貨號：
    CSB-EP887959HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人VPS11重組蛋白
  • 貨號：
    CSB-BP887959HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人VPS11重組蛋白
  • 貨號：
    CSB-MP887959HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    END1; HGNC:14583; hVPS11; PEP5; PP3476; RING finger protein 108; RNF108; Vacuolar protein sorting 11 (yeast homolog); Vacuolar protein sorting 11 (yeast); Vacuolar protein sorting 11 homolog (S. cerevisiae); Vacuolar protein sorting 11 homolog; Vacuolar protein sorting associated protein 11 homolog; Vacuolar protein sorting protein 11; Vacuolar protein sorting-associated protein 11 homolog; vps11; VPS11_HUMAN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Required for fusion of endosomes and autophagosomes with lysosomes. Involved in cargo transport from early to late endosomes and required for the transition from early to late endosomes. Involved in the retrograde Shiga toxin transport.
  • 基因功能參考文獻：
    1. Underlining the presumed pathogenic potential of VPS11 defects. PMID: 27473128
    2. our study reveals a defect in VPS11 as the underlying etiology for an autosomal recessive leukoencephalopathy disorder associated with a dysfunctional autophagy-lysosome trafficking pathway PMID: 27120463
    3. In Ashkenazi-Jewish patients, syndrome with hypomyelination, developmental delay, increasing appendicular spasticity, truncal hypotonia and acquired microcephaly is associated with VPS11 missense mutation, p.Cys846Gly. PMID: 26307567
  • 相關疾病：
    Leukodystrophy, hypomyelinating, 12 (HLD12)
  • 亞細胞定位：
    Endosome. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Cytoplasmic vesicle. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, clathrin-coated vesicle.
  • 蛋白家族：
    VPS11 family
  • 組織特異性：
    Ubiquitous. Expression was highest in heart and low in lung.
  • 數據庫鏈接：

    HGNC: 14583

    OMIM: 608549

    KEGG: hsa:55823

    UniGene: Hs.234282



主站蜘蛛池模板： 亚洲国产成人无码精品| 亚洲伊人成综合人影院青青青| 午夜伦yy44880影院| 亚洲精品无码国产| 人妻少妇88久久中文字幕| 久久久久国产精品嫩草影院| 精品久久久噜噜噜久久久| 午夜成人爽爽爽视频在线观看| 巨大乳女人做爰视频在线看| 亚洲无线卡一卡二| 亚洲日韩欧洲乱码av夜夜摸| 久久天天躁夜夜躁狠狠躁2022| 黑人巨大无码中文字幕无码| 综合色就爱涩涩涩综合婷婷| 久久人妻av一区二区软件| 色狠狠一区二区三区香蕉| 午夜亚洲国产理论片中文飘花| 国产免费午夜a无码v视频| 少妇太爽了在线观看| 欧美熟妇性开放| 午夜福利不卡在线视频| 国内精品伊人久久久久网站| 在线成人www免费观看视频| 女人和拘做爰正片视频| 丁香五月缴情在线| 无码专区6080yy国产电影| 免费无码又爽又高潮视频| 国产精品高清视亚洲中文| 午夜性色福利在线视频福利| 人妻av无码中文专区久久| 妺妺窝人体色www看美女| 亚洲夜色噜噜av在线观看| 国产精品成人观看视频| 无码熟妇人妻av在线电影| 五月婷婷俺也去开心| 免费观看潮喷到高潮中文字幕| 产后漂亮奶水人妻无码| 男人添女人囗交做爰视频| 色护士极品影院| 免费人成视频网站在线下载| 精品露脸国产偷人在视频|