在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

VPS11 Antibody

  • 中文名稱:
    VPS11兔多克隆抗體
  • 貨號:
    CSB-PA025889GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    END1 antibody; HGNC:14583 antibody; hVPS11 antibody; PEP5 antibody; PP3476 antibody; RING finger protein 108 antibody; RNF108 antibody; Vacuolar protein sorting 11 (yeast homolog) antibody; Vacuolar protein sorting 11 (yeast) antibody; Vacuolar protein sorting 11 homolog (S. cerevisiae) antibody; Vacuolar protein sorting 11 homolog antibody; Vacuolar protein sorting associated protein 11 homolog antibody; Vacuolar protein sorting protein 11 antibody; Vacuolar protein sorting-associated protein 11 homolog antibody; vps11 antibody; VPS11_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human VPS11
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Required for fusion of endosomes and autophagosomes with lysosomes. Involved in cargo transport from early to late endosomes and required for the transition from early to late endosomes. Involved in the retrograde Shiga toxin transport.
  • 基因功能參考文獻:
    1. Underlining the presumed pathogenic potential of VPS11 defects. PMID: 27473128
    2. our study reveals a defect in VPS11 as the underlying etiology for an autosomal recessive leukoencephalopathy disorder associated with a dysfunctional autophagy-lysosome trafficking pathway PMID: 27120463
    3. In Ashkenazi-Jewish patients, syndrome with hypomyelination, developmental delay, increasing appendicular spasticity, truncal hypotonia and acquired microcephaly is associated with VPS11 missense mutation, p.Cys846Gly. PMID: 26307567
  • 相關疾病:
    Leukodystrophy, hypomyelinating, 12 (HLD12)
  • 亞細胞定位:
    Endosome. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Cytoplasmic vesicle. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, clathrin-coated vesicle.
  • 蛋白家族:
    VPS11 family
  • 組織特異性:
    Ubiquitous. Expression was highest in heart and low in lung.
  • 數據庫鏈接:

    HGNC: 14583

    OMIM: 608549

    KEGG: hsa:55823

    UniGene: Hs.234282



主站蜘蛛池模板: 亚洲无日韩码精品| 97国产精东麻豆人妻电影| 亚洲欧美日韩综合在线一| 果冻传媒一区二区天美传媒| 果冻传媒亚洲区二期| 免费看成人aa片无码视频羞羞网 | 少妇做爰免费视频了| 97午夜理论片在线影院| 久久香蕉国产线看观看手机| 国语少妇高潮对白在线| 偷偷色噜狠狠狠狠的777米奇| 3d动漫精品啪啪一区二区免费| 手机在线看片| 久久人人妻人人爽人人爽| 国产成人精品免费午夜app| 亚洲成av人片香蕉片| _97夜夜澡人人爽人人喊_欧美| 五月综合色婷婷在线观看| 日亚韩在线无码一区二区三区| 成人性做爰aaa片免费| 春色校园综合人妻av| 欧美品无码一区二区三区在线蜜桃| 亚洲精品午夜一区人人爽| 狠狠综合久久综合88亚洲| 国产欧美综合一区二区三区| 玩弄少妇的肉体k8经典| 产精品视频在线观看免费 | 蜜桃av抽搐高潮一区二区| 亚洲精品1卡2卡三卡4卡乱码| 日本少妇内射视频播放舔| 377p欧洲日本亚洲大胆| 久久人人爽人人爽人人片av麻烦| 亚洲一二三四2021不卡| 最近中文字幕mv在线视频看| 黑人强辱丰满的人妻熟女| 大肉大捧一进一出好爽app| 国产亚洲aⅴ在线电影| 久久无码高潮喷水| 亚洲h在线播放在线观看h| 亚洲成国产人片在线观看| 日韩av无码精品一二三区|