在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Uncharacterized protein C20orf72 (C20orf72), partial

Recombinant Human Uncharacterized protein C20orf72 (C20orf72), partial

  • 中文名稱：
    人MGME1重組蛋白
  • 貨號：
    CSB-YP880084HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人MGME1重組蛋白
  • 貨號：
    CSB-EP880084HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人MGME1重組蛋白
  • 貨號：
    CSB-EP880084HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人MGME1重組蛋白
  • 貨號：
    CSB-BP880084HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人MGME1重組蛋白
  • 貨號：
    CSB-MP880084HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    MGME1
  • Uniprot No.：
  • 別名：
    MGME1; C20orf72; DDK1Mitochondrial genome maintenance exonuclease 1; EC 3.1.-.-
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 表達區(qū)域：
    -
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
  • 基因功能參考文獻：
    1. MGME1 is part of a termination complex acting at the end of the D-loop region where it modulates mtDNA replication and H-strand transcription termination PMID: 29572490
    2. A novel frameshift deletion in MGME1 causes early onset cerebellar ataxia. PMID: 28711739
    3. MGME1 processes flaps into ligatable nicks in concert with DNA polymerase gamma during mtDNA replication. PMID: 27220468
    4. MGME1-mediated mtDNA processing is essential for faithful mitochondrial genome replication and might be required for intramolecular recombination of mtDNA. PMID: 24986917
    5. Overexperssion of Ddk1 decreases the levels of 7S DNA, suggesting an important role of the protein in 7S DNA regulation. PMID: 23358826
    6. Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease. PMID: 23313956

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Mitochondrial DNA depletion syndrome 11 (MTDPS11)
  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    MGME1 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16205

    OMIM: 615076

    KEGG: hsa:92667

    STRING: 9606.ENSP00000366939

    UniGene: Hs.320823



主站蜘蛛池模板： 亚洲精品国男人在线视频| 奇米777国产在线视频| 精品国产乱码久久久久久影片| 又爽又黄又无遮挡的激情视频| 成人综合婷婷国产精品久久 | 国产av一二三无码影片| 9999国产精品欧美久久久久久| 天天摸夜夜摸夜夜狠狠摸| 国产萌白酱喷水视频在线观看| 色惰日本视频网站www| 人妻换人妻仑乱| 日本免费一区二区三区视频观看 | 日日做夜狠狠爱欧美黑人| 99精品视频在线观看| 久久99国产综合精品| 骚动漫十八禁在线观看| 国产成人亚洲综合无码18禁h| 无码成人aaaaa毛片| 国产精品日韩欧美一区二区三区 | 欧美成人精品三级网站视频| 疯狂做受xxxx高潮欧美日本| xx性欧美肥妇精品久久久久久| 妺妺窝人体色www在线观看 | 欧美深性狂猛ⅹxxx深喉| 久久久久亚洲精品中文字幕| 人妻av乱片av出轨av| 亚洲欧美在线制服丝袜国产| 97久章草在线视频播放| www国产亚洲精品久久麻豆| 乱色精品无码一区二区国产盗| 麻花传媒mv国产免费观看视频| 国产精品无需播放器在线观看| 久久天堂av综合合色蜜桃网| 久久久久久久女国产乱让韩 | 男女啪啪免费观看的网址| 成人区精品一区二区不卡| 亚洲人精品午夜射精日韩| 国产精品亚洲二区在线观看| 婷婷成人小说综合专区| 国产无套粉嫩白浆在线| 国产精品老熟女露脸视频|