在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Uncharacterized protein C20orf72 (C20orf72), partial

Recombinant Human Uncharacterized protein C20orf72 (C20orf72), partial

  • 中文名稱：
    人MGME1重組蛋白
  • 貨號：
    CSB-YP880084HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人MGME1重組蛋白
  • 貨號：
    CSB-EP880084HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人MGME1重組蛋白
  • 貨號：
    CSB-EP880084HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人MGME1重組蛋白
  • 貨號：
    CSB-BP880084HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人MGME1重組蛋白
  • 貨號：
    CSB-MP880084HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    MGME1
  • Uniprot No.：
  • 別名：
    MGME1; C20orf72; DDK1Mitochondrial genome maintenance exonuclease 1; EC 3.1.-.-
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 表達區(qū)域：
    -
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
  • 基因功能參考文獻：
    1. MGME1 is part of a termination complex acting at the end of the D-loop region where it modulates mtDNA replication and H-strand transcription termination PMID: 29572490
    2. A novel frameshift deletion in MGME1 causes early onset cerebellar ataxia. PMID: 28711739
    3. MGME1 processes flaps into ligatable nicks in concert with DNA polymerase gamma during mtDNA replication. PMID: 27220468
    4. MGME1-mediated mtDNA processing is essential for faithful mitochondrial genome replication and might be required for intramolecular recombination of mtDNA. PMID: 24986917
    5. Overexperssion of Ddk1 decreases the levels of 7S DNA, suggesting an important role of the protein in 7S DNA regulation. PMID: 23358826
    6. Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease. PMID: 23313956

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Mitochondrial DNA depletion syndrome 11 (MTDPS11)
  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    MGME1 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16205

    OMIM: 615076

    KEGG: hsa:92667

    STRING: 9606.ENSP00000366939

    UniGene: Hs.320823



主站蜘蛛池模板： 丰满岳乱妇在线观看中字| 国产精品无码专区| 蜜臀av人妻国产精品建身房| 午夜阳光精品一区二区三区| 亚洲天堂2017无码中文| 国产α片免费观看在线人| 成人午夜免费无码区| 56pao国产成视频永久| 国产精品一区二区久久不卡| 97在线视频人妻无码| 日韩高清亚洲日韩精品一区| 午夜香蕉成视频人网站| 人妻少妇av中文字幕乱码| 欧美老人巨大xxxx做受视频 | 色噜噜狠狠狠狠色综合久一 | 亚洲va欧美va天堂v国产综合 | a∨变态另类天堂无码专区| 日本一区二区三区免费播放视频站 | 在线中文字幕乱码英文字幕正常| 丰满多毛的陰户视频| 亚洲人成网站18禁止一区| 国产精品无码制服丝袜| 免费观看又污又黄在线观看| 国产性色av一区二区三区| 国产成人精品aa毛片| 精品人妻大屁股白浆无码| 国产精品狼人久久久久影院| 日本一卡2卡3卡4卡5卡精品视频| 97久久精品人人槡人妻人| 免费久久人人爽人人爽av| 亚洲有无码av在线播放| 成人无码视频97免费| 97久久超碰国产精品旧版麻豆| 久久精品国产久精国产| 国产偷人妻精品一区| 五月激激激综合网亚洲| 国产卡1卡2卡3麻豆精品免费| 少妇极品熟妇人妻| 久热这里只精品99国产6-99re视…| 欧美成人性做爰77777| 精品久久久无码中文字幕 |