在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MGME1 Antibody, Biotin conjugated

MGME1 Antibody, Biotin conjugated

  • 中文名稱：
    MGME1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA880084LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MGME1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MGME1
  • 別名：
    MGME1 antibody; C20orf72 antibody; DDK1Mitochondrial genome maintenance exonuclease 1 antibody; EC 3.1.-.- antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Mitochondrial genome maintenance exonuclease 1 protein (81-260AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
  • 基因功能參考文獻(xiàn)：
    1. MGME1 is part of a termination complex acting at the end of the D-loop region where it modulates mtDNA replication and H-strand transcription termination PMID: 29572490
    2. A novel frameshift deletion in MGME1 causes early onset cerebellar ataxia. PMID: 28711739
    3. MGME1 processes flaps into ligatable nicks in concert with DNA polymerase gamma during mtDNA replication. PMID: 27220468
    4. MGME1-mediated mtDNA processing is essential for faithful mitochondrial genome replication and might be required for intramolecular recombination of mtDNA. PMID: 24986917
    5. Overexperssion of Ddk1 decreases the levels of 7S DNA, suggesting an important role of the protein in 7S DNA regulation. PMID: 23358826
    6. Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease. PMID: 23313956

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Mitochondrial DNA depletion syndrome 11 (MTDPS11)
  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    MGME1 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16205

    OMIM: 615076

    KEGG: hsa:92667

    STRING: 9606.ENSP00000366939

    UniGene: Hs.320823



主站蜘蛛池模板： 欧美 变态 另类 人妖| 亚洲精品亚洲人成在线下载 | 久久男人av资源网站| 西西人体午夜大胆无码视频| 欧美牲交a欧美牲交| 老子午夜精品无码| 无码精品国产一区二区免费| 老湿机香蕉久久久久久| 精品国内在视频线2019| 五十老熟妇乱子伦免费观看| 亚洲欧美日韩视频高清专区| 婷婷丁香五月亚洲中文字幕| 国产av熟女一区二区三区 | 18禁止看的免费污网站| 精品三级av无码一区| 奇米在线7777在线精品 | 在线成人精品国产区免费| 男女啪祼交视频| 国产不卡视频一区二区三区| 欧美丰腴丰满大屁股熟妇| 天天av天天av天天透| 日韩高清国产一区在线| 久久精品人妻少妇一区二区三区| 欧美极p品少妇的xxxxx| 少妇精品揄拍高潮少妇| 一本大道无码人妻精品专区| 性荡视频播放在线视频 | 亚洲乱码中文字幕手机在线| 中国妇女做爰视频| 亚洲一本大道av久在线播放| 男女午夜猛烈啪啦啦视频| 在线看片福利无码网址| √天堂中文www官网在线| 亚洲日韩在线中文字幕综合 | 亚洲综合激情另类专区| 国产情侣久久久久aⅴ免费| 亚洲国产精品无码中文在线| 一区二区三区av高清免费波多| 久久精品国产99精品国产2021| 日韩av无码成人无码免费| 四虎永久在线精品免费观看|