在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MGME1 Antibody

  • 中文名稱:
    MGME1兔多克隆抗體
  • 貨號(hào):
    CSB-PA880084LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: MGME1 antibody at 1μg/ml
      Lane 1: Jurkat whole cell lysate
      Lane 2: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 39 kDa
      Observed band size: 39 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA880084LA01HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) MGME1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MGME1
  • 別名:
    MGME1 antibody; C20orf72 antibody; DDK1Mitochondrial genome maintenance exonuclease 1 antibody; EC 3.1.-.- antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Mitochondrial genome maintenance exonuclease 1 protein (81-260AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁(yè)面中的產(chǎn)品,MGME1 Antibody (CSB-PA880084LA01HU),的標(biāo)記方式是Non-conjugated。對(duì)于MGME1 Antibody,我們還提供其他標(biāo)記。見下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA880084LB01HU MGME1 Antibody, HRP conjugated ELISA
    FITC CSB-PA880084LC01HU MGME1 Antibody, FITC conjugated
    Biotin CSB-PA880084LD01HU MGME1 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
  • 基因功能參考文獻(xiàn):
    1. MGME1 is part of a termination complex acting at the end of the D-loop region where it modulates mtDNA replication and H-strand transcription termination PMID: 29572490
    2. A novel frameshift deletion in MGME1 causes early onset cerebellar ataxia. PMID: 28711739
    3. MGME1 processes flaps into ligatable nicks in concert with DNA polymerase gamma during mtDNA replication. PMID: 27220468
    4. MGME1-mediated mtDNA processing is essential for faithful mitochondrial genome replication and might be required for intramolecular recombination of mtDNA. PMID: 24986917
    5. Overexperssion of Ddk1 decreases the levels of 7S DNA, suggesting an important role of the protein in 7S DNA regulation. PMID: 23358826
    6. Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease. PMID: 23313956

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Mitochondrial DNA depletion syndrome 11 (MTDPS11)
  • 亞細(xì)胞定位:
    Mitochondrion.
  • 蛋白家族:
    MGME1 family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 16205

    OMIM: 615076

    KEGG: hsa:92667

    STRING: 9606.ENSP00000366939

    UniGene: Hs.320823



主站蜘蛛池模板: av区无码字幕中文色| 午夜福利一区二区三区高清视频| 2020最新国产在线不卡a| 久久婷婷综合缴情亚洲狠狠_| 好紧好爽好深再快点av在线| 国产精品 中文字幕 亚洲 欧美| 国产日产欧产精品网站| 日本无遮挡边做边爱边摸 | 亚洲精品国产精品国自产观看| 久热在线中文字幕色999舞| 日日摸天天碰中文字幕你懂的| 四虎成人永久在线精品免费| 在线人视频观看免费| 一区二区三区在线 | 日本| 放荡的少妇2欧美版| 成人av无码一区二区三区| 久久综合狠狠色综合伊人| 亚洲 另类 日韩 制服 无码| 免费va人成视频网站全| 国产小屁孩cao大人免费| 婷婷亚洲综合五月天小说| 国产舌乚八伦偷品w中| 97国产精品人妻无码久久久| 美女被啪到深处抽搐视频| 十八禁无码免费网站| а√在线中文网新版地址在线 | 成人无码无遮挡很h在线播放| 欧美一区二区三区红桃小说| 亚洲人成电影在线观看影院| 性xxxxx大片免费视频| 成人一区二区免费中文字幕视频| 青青草国产免费国产是公开| 国精产品一区一区三区有限公司| 无码精品人妻一区二区三区影院| 又大又黄又粗又爽的免费视频| 亚洲午夜久久久久妓女影院| 一区二区在线 | 国| 国产精品免费看久久久无码| 亚洲区日韩精品中文字幕| 国产精品久久久久不卡绿巨人| 欧美激情猛片xxxⅹ大3|