在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Cadherin-6(CDH6),partial (Active)

In Stock
  • 貨號:
    CSB-MP005055HU1
  • 規(guī)格:
    ¥624
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Activity
      Measured by its binding ability in a functional ELISA. Immobilized Human CDH6 at 2μg/mL can bind Anti-CDH6 recombinant antibody (CSB-RA005055MA1HU),the EC50 is 2.421-2.802 ng/mL. Biological Activity Assay
  • 其他:

產品詳情

  • 純度:
    Greater than 95% as determined by SEC-HPLC.
  • 內毒素:
    Less than 1.0 EU/ug as determined by LAL method.
  • 生物活性:
    Measured by its binding ability in a functional ELISA. Immobilized Human CDH6 at 2 μg/mL can bind Anti-CDH6 recombinant antibody (CSB-RA005055MA1HU). The EC50 is 2.421-2.802 ng/mL.
  • 基因名:
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    Mammalian cell
  • 分子量:
    63.9 kDa
  • 表達區(qū)域:
    54-615aa
  • 氨基酸序列
    SWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVGENAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGA
  • 蛋白標簽:
    C-terminal 10xHis-tagged
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from a 0.2 μm sterile filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
  • 基因功能參考文獻:
    1. Tumor suppressor genes deleted in liver cancer 1 (DLC1), F-box/WD-repeat-containing protein 7 (FBXW7), and cadherin-6 (CDH6) were identified as presumed targets in Cholangiocarcinoma (CC).Inverse correlation between promoter methylation and expression suggested miR-129-2 and members of the miR-200 family (miR-200a, miR-200b, and miR-429) as novel tumor suppressors and oncomiRs, respectively, in CC PMID: 27593557
    2. The chromatin modifications were determined at five PRC2 targets commonly underexpressed in multiple myeloma (CIITA, CXCL12, GATA2, CDH6 and ICSBP/IRF8). The selected genes were confirmed to be underexpressed in MM compared to normal plasma cells. PMID: 20634887
  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.
  • 數據庫鏈接:

    HGNC: 1765

    OMIM: 603007

    KEGG: hsa:1004

    STRING: 9606.ENSP00000265071

    UniGene: Hs.124776



主站蜘蛛池模板: 99精品视频九九精品视频| 国产无遮挡又爽又黄的视频| 欧美精品一国产成人综合久久| 毛片无码国产| 亚洲在线国产日韩欧美| 国产aⅴ精品一区二区三区久久| 国产亚洲人成无码网在线观看| 亚洲熟妇自偷自拍另类| 日韩精品极品视频在线观看免费| 永久黄网站免费视频性色| 国产成人a在线观看视频| 国产精品va无码免费| 欧美成人精品高清视频在线观看| 麻豆亚洲一区| 久久精品人妻一区二区三区 | 俺也来俺也去俺也射| 日本久久综合久久综合| 亚洲精品中文字幕乱码4区| 97精品人人妻人人| 免费观看又色又爽又黄的韩国| 欧美激情猛片xxxⅹ大3| 伊人久久大香线蕉av五月天| 强行糟蹋人妻hd中文字幕| 男人女人午夜视频免费| 人人婷婷人人澡人人爽| 东京热人妻丝袜无码av一二三区观| 风流少妇又紧又爽又丰满| 亚洲色播爱爱爱爱爱爱爱| 国产在线拍揄自揄视频网试看| 亚洲视频日韩视欧美视频| 欧洲精品码一区二区三区免费看| 波多野结衣网站| 国产成人无码av在线播放不卡| 毛片无遮挡高清免费| 爆乳女仆高潮在线观看| 亚洲中文字幕婷婷在线| 无码精品久久久天天影视| 亚洲精品国偷自产在线| 99久久精品美女高潮喷水| 中文字幕无码精品亚洲资源网 | 国产老熟女伦老熟妇露脸|