在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Fanconi anemia group G protein (FANCG)

Recombinant Human Fanconi anemia group G protein (FANCG)

  • 中文名稱(chēng)：
    人FANCG重組蛋白
  • 貨號(hào)：
    CSB-YP008419HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    人FANCG重組蛋白
  • 貨號(hào)：
    CSB-EP008419HU
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    人FANCG重組蛋白
  • 貨號(hào)：
    CSB-EP008419HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    人FANCG重組蛋白
  • 貨號(hào)：
    CSB-BP008419HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    人FANCG重組蛋白
  • 貨號(hào)：
    CSB-MP008419HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    FANCG
  • Uniprot No.：
  • 別名：
    DNA repair protein XRCC9; FAG; FANCG; FANCG_HUMAN; Fanconi anaemia complementation group G; Fanconi anemia group G protein; Protein FACG; X ray repair; complementing defective; in Chinese hamster cells 9; X-ray repair; complementing defective; in Chinese hamster; 9; XRCC9
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Full length protein
  • 表達(dá)區(qū)域：
    1-622
  • 氨基酸序列
    MSRQTTSVGS SCLDLWREKN DRLVRQAKVA QNSGLTLRRQ QLAQDALEGL RGLLHSLQGL PAAVPVLPLE LTVTCNFIIL RASLAQGFTE DQAQDIQRSL ERVLETQEQQ GPRLEQGLRE LWDSVLRASC LLPELLSALH RLVGLQAALW LSADRLGDLA LLLETLNGSQ SGASKDLLLL LKTWSPPAEE LDAPLTLQDA QGLKDVLLTA FAYRQGLQEL ITGNPDKALS SLHEAASGLC PRPVLVQVYT ALGSCHRKMG NPQRALLYLV AALKEGSAWG PPLLEASRLY QQLGDTTAEL ESLELLVEAL NVPCSSKAPQ FLIEVELLLP PPDLASPLHC GTQSQTKHIL ASRCLQTGRA GDAAEHYLDL LALLLDSSEP RFSPPPSPPG PCMPEVFLEA AVALIQAGRA QDALTLCEEL LSRTSSLLPK MSRLWEDARK GTKELPYCPL WVSATHLLQG QAWVQLGAQK VAISEFSRCL ELLFRATPEE KEQGAAFNCE QGCKSDAALQ QLRAAALISR GLEWVASGQD TKALQDFLLS VQMCPGNRDT YFHLLQTLKR LDRRDEATAL WWRLEAQTKG SHEDALWSLP LYLESYLSWI RPSDRDAFLE EFRTSLPKSC DL
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
  • 基因功能參考文獻(xiàn)：
    1. LOH may predominantly indicate copy number gains in FANCF and losses in FANCG and BRIP1. Integration of copy number data and gene expression proved difficult as the available sample sets did not overlap. PMID: 28440438
    2. studied the impact of mutations on the function and structure of FANCG PMID: 28024295
    3. a systems biology approach for elucidating the therapeutic potential of curcumin against FA and leukemia is investigated by analyzing the computational molecular interactions of curcumin ligand with FANC G of FA and seven other key disease targets of leukemia PMID: 27608133
    4. Patients, homozygous for the FANCG founder mutation, present with severe cytopenia but progress to bone marrow failure at similar ages to other individuals affected with Fanconi anemia of heterogeneous genotype. PMID: 25477267
    5. founder haplotype analysis of FANCG for the Korean Fanconi anemia population PMID: 25703136
    6. A new role of FANCG in Homologous recombination repair of interstrand crosslinks through K63Ub-mediated interaction with the Rap80-BRCA1 complex. PMID: 25132264
    7. Three novel single base pair deletions, resulting in frameshift mutations (c.247delA, c.179delT and c.899delT) were identified in patients with Fanconi anaemia PMID: 24300640
    8. Areca nut extracts-induced miR-23a was correlated with a reduced FANCG expression and DSB repair, which might contribute to ANE-associated human malignancies. PMID: 21750350
    9. Study of the molecular evolution of FA genes using database search methods such as PSI-BLAST suggested that FANCG may contain a known domain, and that this protein is a member of the family of tetratricopeptide repeat-containing proteins. PMID: 12432219
    10. There is remarkably lage sequence variation in FANCG gene mutations and polymorphisms across ethnic and racial backgrounds found in the International Fanconi Anemia Registry they include IVS8-2A>G, IVS11+1G>c, 1794_1803del10, and IVS3+1G>C. PMID: 12552564
    11. FANCG was able to mediate interaction between FANCA and FANCF, as well as between monomers of FANCA PMID: 12649160
    12. FANCG is required for efficient homologous recombination-mediated repair of at least some types of DNA double-strand breaks PMID: 12861027
    13. FANCG interacts directly with BRCA2. PMID: 12915460
    14. A unique Fanconi-anemia-causing mutation, FANCG splice-site mutation IVS4+3A>G, showed exon 4 skipping. PMID: 15059067
    15. Primary fibroblasts from patients with Fanconi anemia with reduced FANCG expression show no signs of telomere dysfunction. PMID: 15319283
    16. FANCG, in addition to stabilising the FA core complex, may have a role in building multiprotein complexes that facilitate homologous recombination repair. PMID: 16621732
    17. Four human FANCG polymorphic variants show normal biological function. PMID: 17010390

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Fanconi anemia complementation group G (FANCG)
  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
  • 組織特異性：
    Highly expressed in testis and thymus. Found in lymphoblasts.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 3588

    OMIM: 602956

    KEGG: hsa:2189

    STRING: 9606.ENSP00000367910

    UniGene: Hs.591084



主站蜘蛛池模板： 天干天干天啪啪夜爽爽99| 亚洲国产av精品一区二区蜜芽| 久久亚洲中文字幕无码| 久久先锋男人av资源网站| 国产成人av国语在线观看| 欧美饥渴少妇xxxxx性| 一二三四区无产乱码1000集| 亚洲欧美一区二区成人片| 国产高清不卡无码视频| 久久国产人妻一区二区免费| 在线观看老湿视频福利| 亚洲综合色区在线观看| 中文人妻熟妇乱又伦精品| 99久久伊人精品综合观看| 国产一性一交一伦一a片| 色综合色综合久久综合频道88| 国产精品久久久久久无码五月 | 欧美一区二区三区啪啪| 一边捏奶头一边啪高潮视频| 色哟哟免费视频播放网站| 超薄丝袜足j好爽在线| 久久久无码精品亚洲日韩蜜桃| 国产成人亚洲精品另类动态| 免费网站内射红桃视频| 国产伦精品免编号公布| 国产福利精品一区二区| 无码中文字幕免费一区二区三区| 久久av高潮av无码av喷吹| 日产一区日产2区| 亚洲精品成人老司机影视| 国产精品无码av不卡顿| 丰满女人又爽又紧又丰满| 国产在线观看无码的免费网站 | 亚洲欧美日韩在线不卡| 人人爽人人爽人人片a| 亚洲欧洲综合有码无码| 四虎国产精品永久在线观看| 亚洲人成人无码网www国产 | 在线a亚洲v天堂网2018| 中文在线8资源库| 亚洲欧美综合中文|