在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FANCG Antibody

  • 中文名稱(chēng):
    FANCG兔多克隆抗體
  • 貨號(hào):
    CSB-PA098906
  • 規(guī)格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA098906(FANCG Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA098906(FANCG Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    FANCG
  • 別名:
    DNA repair protein XRCC9 antibody; FAG antibody; FANCG antibody; FANCG_HUMAN antibody; Fanconi anaemia complementation group G antibody; Fanconi anemia group G protein antibody; Protein FACG antibody; X ray repair; complementing defective; in Chinese hamster cells 9 antibody; X-ray repair; complementing defective; in Chinese hamster; 9 antibody; XRCC9 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Fusion protein of Human FANCG
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
  • 基因功能參考文獻(xiàn):
    1. LOH may predominantly indicate copy number gains in FANCF and losses in FANCG and BRIP1. Integration of copy number data and gene expression proved difficult as the available sample sets did not overlap. PMID: 28440438
    2. studied the impact of mutations on the function and structure of FANCG PMID: 28024295
    3. a systems biology approach for elucidating the therapeutic potential of curcumin against FA and leukemia is investigated by analyzing the computational molecular interactions of curcumin ligand with FANC G of FA and seven other key disease targets of leukemia PMID: 27608133
    4. Patients, homozygous for the FANCG founder mutation, present with severe cytopenia but progress to bone marrow failure at similar ages to other individuals affected with Fanconi anemia of heterogeneous genotype. PMID: 25477267
    5. founder haplotype analysis of FANCG for the Korean Fanconi anemia population PMID: 25703136
    6. A new role of FANCG in Homologous recombination repair of interstrand crosslinks through K63Ub-mediated interaction with the Rap80-BRCA1 complex. PMID: 25132264
    7. Three novel single base pair deletions, resulting in frameshift mutations (c.247delA, c.179delT and c.899delT) were identified in patients with Fanconi anaemia PMID: 24300640
    8. Areca nut extracts-induced miR-23a was correlated with a reduced FANCG expression and DSB repair, which might contribute to ANE-associated human malignancies. PMID: 21750350
    9. Study of the molecular evolution of FA genes using database search methods such as PSI-BLAST suggested that FANCG may contain a known domain, and that this protein is a member of the family of tetratricopeptide repeat-containing proteins. PMID: 12432219
    10. There is remarkably lage sequence variation in FANCG gene mutations and polymorphisms across ethnic and racial backgrounds found in the International Fanconi Anemia Registry they include IVS8-2A>G, IVS11+1G>c, 1794_1803del10, and IVS3+1G>C. PMID: 12552564
    11. FANCG was able to mediate interaction between FANCA and FANCF, as well as between monomers of FANCA PMID: 12649160
    12. FANCG is required for efficient homologous recombination-mediated repair of at least some types of DNA double-strand breaks PMID: 12861027
    13. FANCG interacts directly with BRCA2. PMID: 12915460
    14. A unique Fanconi-anemia-causing mutation, FANCG splice-site mutation IVS4+3A>G, showed exon 4 skipping. PMID: 15059067
    15. Primary fibroblasts from patients with Fanconi anemia with reduced FANCG expression show no signs of telomere dysfunction. PMID: 15319283
    16. FANCG, in addition to stabilising the FA core complex, may have a role in building multiprotein complexes that facilitate homologous recombination repair. PMID: 16621732
    17. Four human FANCG polymorphic variants show normal biological function. PMID: 17010390

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Fanconi anemia complementation group G (FANCG)
  • 亞細(xì)胞定位:
    Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
  • 組織特異性:
    Highly expressed in testis and thymus. Found in lymphoblasts.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 3588

    OMIM: 602956

    KEGG: hsa:2189

    STRING: 9606.ENSP00000367910

    UniGene: Hs.591084



主站蜘蛛池模板: 久久久精品国产免大香伊| 国产欧美国日产高清| 欧美性xxxxx极品少妇直播| 亚洲伊人久久综合影院| 99精品国产兔费观看久久| 日韩人妻无码精品久久| 漂亮人妻被强中文字幕久久| 成人性生交大片免费看中文| 99久久久无码国产精品免费| 国产又色又爽无遮挡免费| 亚洲国产激情一区二区三区| 亚洲aⅴ天堂av天堂无码 | 久久久久成人精品无码| 国产综合精品一区二区三区 | 欧美日产国产新一区| 午夜亚洲精品久久一区二区| 中文字幕人妻色偷偷久久| 少妇白浆高潮无码免费区| 欧美嫩交一区二区三区| 欧美精品无码久久久久久| 妺妺窝人体色www在线下载| 日本丰满妇人成熟免费中文字幕| 亚洲欧美日韩国产成人一区| 午夜无码成人免费视频| 毛片免费视频肛交颜射免费视频| 国产亚洲视频在线观看播放| 日产欧美国产日韩精品| 在线观看国产精品普通话对白精品| 无罩大乳的熟妇正在播放| 国产成人+亚洲欧洲+综合| 久久国产精品日本波多野结衣| 国产精品区av| 成人综合网站| 成年性午夜无码免费视频| 国产精品99久久久久久董美香| 国产精品户外野外| 国产精品亚洲精品日韩已满| 日韩国产亚洲一区二区三区| 国精一二二产品无人区免费应用| 中文字幕乱码中文乱码51精品| 亚洲午夜无码极品久久|