在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FANCG Antibody

  • 中文名稱:
    FANCG兔多克隆抗體
  • 貨號:
    CSB-PA008419GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    FANCG
  • 別名:
    DNA repair protein XRCC9 antibody; FAG antibody; FANCG antibody; FANCG_HUMAN antibody; Fanconi anaemia complementation group G antibody; Fanconi anemia group G protein antibody; Protein FACG antibody; X ray repair; complementing defective; in Chinese hamster cells 9 antibody; X-ray repair; complementing defective; in Chinese hamster; 9 antibody; XRCC9 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human FANCG
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
  • 基因功能參考文獻(xiàn):
    1. LOH may predominantly indicate copy number gains in FANCF and losses in FANCG and BRIP1. Integration of copy number data and gene expression proved difficult as the available sample sets did not overlap. PMID: 28440438
    2. studied the impact of mutations on the function and structure of FANCG PMID: 28024295
    3. a systems biology approach for elucidating the therapeutic potential of curcumin against FA and leukemia is investigated by analyzing the computational molecular interactions of curcumin ligand with FANC G of FA and seven other key disease targets of leukemia PMID: 27608133
    4. Patients, homozygous for the FANCG founder mutation, present with severe cytopenia but progress to bone marrow failure at similar ages to other individuals affected with Fanconi anemia of heterogeneous genotype. PMID: 25477267
    5. founder haplotype analysis of FANCG for the Korean Fanconi anemia population PMID: 25703136
    6. A new role of FANCG in Homologous recombination repair of interstrand crosslinks through K63Ub-mediated interaction with the Rap80-BRCA1 complex. PMID: 25132264
    7. Three novel single base pair deletions, resulting in frameshift mutations (c.247delA, c.179delT and c.899delT) were identified in patients with Fanconi anaemia PMID: 24300640
    8. Areca nut extracts-induced miR-23a was correlated with a reduced FANCG expression and DSB repair, which might contribute to ANE-associated human malignancies. PMID: 21750350
    9. Study of the molecular evolution of FA genes using database search methods such as PSI-BLAST suggested that FANCG may contain a known domain, and that this protein is a member of the family of tetratricopeptide repeat-containing proteins. PMID: 12432219
    10. There is remarkably lage sequence variation in FANCG gene mutations and polymorphisms across ethnic and racial backgrounds found in the International Fanconi Anemia Registry they include IVS8-2A>G, IVS11+1G>c, 1794_1803del10, and IVS3+1G>C. PMID: 12552564
    11. FANCG was able to mediate interaction between FANCA and FANCF, as well as between monomers of FANCA PMID: 12649160
    12. FANCG is required for efficient homologous recombination-mediated repair of at least some types of DNA double-strand breaks PMID: 12861027
    13. FANCG interacts directly with BRCA2. PMID: 12915460
    14. A unique Fanconi-anemia-causing mutation, FANCG splice-site mutation IVS4+3A>G, showed exon 4 skipping. PMID: 15059067
    15. Primary fibroblasts from patients with Fanconi anemia with reduced FANCG expression show no signs of telomere dysfunction. PMID: 15319283
    16. FANCG, in addition to stabilising the FA core complex, may have a role in building multiprotein complexes that facilitate homologous recombination repair. PMID: 16621732
    17. Four human FANCG polymorphic variants show normal biological function. PMID: 17010390

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Fanconi anemia complementation group G (FANCG)
  • 亞細(xì)胞定位:
    Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
  • 組織特異性:
    Highly expressed in testis and thymus. Found in lymphoblasts.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 3588

    OMIM: 602956

    KEGG: hsa:2189

    STRING: 9606.ENSP00000367910

    UniGene: Hs.591084



主站蜘蛛池模板: 亚洲精品乱码久久久久久蜜桃图片| 亚洲情a成黄在线观看| 亚洲熟妇丰满多毛xxxx| 人妻少妇精品视频一区二区三区| 亚洲va中文字幕无码久久| 亚洲一卡2卡三卡4卡国色天香| 欧洲精品一线二线三线区别| 国产成人av无码精品| 东京热人妻无码一区二区av | 久久午夜无码鲁丝片| 伊人激情av一区二区三区 | 国产午夜精品久久久久免费视| 亚洲一区精品二人人爽久久| 亚洲黑人巨大videos| 久热中文字幕无码视频| 97久久人人超碰超碰窝窝| 亚洲人成在线观看| 国产精品嫩草影院久久| 中文午夜人妻无码看片| 天堂www中文在线资源| 精品国产成人av在线| 国产在线一卡2卡三卡4卡免费| 成 人 社区在线视频| 国产精品无码午夜福利| 国产精品无码成人午夜电影| 中国农村妇女真实bbwbbwbbw| 午夜亚洲国产理论片二级港台二级| 欧美国产一区二区三区激情无套| 欧牲交a欧美牲交aⅴ| 日韩免费人妻av无码专区蜜桃| 成年女人黄小视频| 亚洲的天堂av无码| 男女性潮高清免费网站| 成人免费播放视频777777| 乱人伦人妻中文字幕无码| 性xxxx欧美老妇胖老太269| 天天爱天天做久久狠狠做| 久久久久久久久888| 国产va在线观看免费| 日韩爆乳一区二区无码| 性高朝久久久久久久久久|