在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Dual specificity protein phosphatase 26 (DUSP26)

  • 中文名稱:
    人DUSP26重組蛋白
  • 貨號:
    CSB-YP863128HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人DUSP26重組蛋白
  • 貨號:
    CSB-EP863128HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人DUSP26重組蛋白
  • 貨號:
    CSB-BP863128HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人DUSP26重組蛋白
  • 貨號:
    CSB-MP863128HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    DUSP26
  • Uniprot No.:
  • 別名:
    DSP-4; Dual specificity phosphatase 26 (putative); Dual specificity phosphatase 26; Dual specificity phosphatase SKRP3; Dual specificity protein phosphatase 26; DUS26_HUMAN; DUSP24; DUSP26; Hypothetical protein FLJ31142; LDP 4; LDP-4; Low molecular mass dual specificity phosphatase 4; Low-molecular-mass dual-specificity phosphatase 4; MAP kinase phosphatase 8; MGC1136; MGC2627; Mitogen activated protein kinase phosphatase 8; Mitogen-activated protein kinase phosphatase 8; MKP-8; MKP8; NATA1; NATA1 protein; Novel amplified gene in thyroid anaplastic cancer; SKRP3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-211
  • 氨基酸序列
    MCPGNWLWAS MTFMARFSRS SSRSPVRTRG TLEEMPTVQH PFLNVFELER LLYTGKTACN HADEVWPGLY LGDQDMANNR RELRRLGITH VLNASHSRWR GTPEAYEGLG IRYLGVEAHD SPAFDMSIHF QTAADFIHRA LSQPGGKILV HCAVGVSRSA TLVLAYLMLY HHLTLVEAIK KVKDHRGIIP NRGFLRQLLA LDRRLRQGLE A
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
  • 基因功能參考文獻:
    1. Enhanced expression of DUSP26 was observed in the hippocampus of Alzheimer's disease patients. PMID: 26924229
    2. results suggest that AK2 is an associated activator of DUSP26 and suppresses cell proliferation by FADD dephosphorylation, postulating AK2 as a negative regulator of tumour growth. PMID: 24548998
    3. The study reports the 1.68 A crystal structure of a catalytically inactive mutant (Cys152Ser) of DUSP26 lacking the first 60 N-terminal residues (DeltaN60-C/S-DUSP26). PMID: 23298255
    4. DUSP26 may function as a tumour suppressor in particular cancers. PMID: 20347885
    5. DUSP26 functions as a p53 phosphatase PMID: 20562916
    6. DUSP26 effectively dephosphorylates p38 and has a little effect on extracellular signal-regulated kinase in anaplastic thyroid cancer. PMID: 16924234
    7. Downregulation of Dusp26 may contribute to malignant phenotypes of glioma. PMID: 19043453

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Golgi apparatus.
  • 蛋白家族:
    Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
  • 組織特異性:
    Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer.
  • 數據庫鏈接:

    HGNC: 28161

    KEGG: hsa:78986

    STRING: 9606.ENSP00000256261

    UniGene: Hs.8719



主站蜘蛛池模板: 久热这里只有精品12| 国模叶桐尿喷337p人体| 亚洲精品熟女国产| 曰批免费视频播放免费直播| 国产成人高清亚洲一区妲妃| 精品久久综合1区2区3区激情| 国产亚av手机在线观看| 日日拍夜夜嗷嗷叫国产| 亚洲综合另类小说色区| 亚洲性av网站| 国产成人亚洲综合| 99蜜桃臀久久久欧美精品网站| 欧美肥婆性猛交xxxx| 巨爆乳中文字幕巨爆区巨爆乳无码 | 一边摸一边叫床一边爽av| 亚洲熟妇色xxxxx欧美老妇y| 精品国产sm最大网免费站| 3p人妻少妇对白精彩视频| 午夜肉伦伦影院| 国产精品天干天干| 美女张开腿让男人桶爽| 国产破外女出血视频| 麻豆国产av丝袜白领传媒| 久久欧美一区二区三区性生奴| 欧美一区二区三区视频在线观看 | 视频在线+欧美十亚洲曰本| 亚洲婷婷五月激情综合app| 国产又黄又爽又色的免费视频 | a亚洲va欧美va国产综合| 国产成人亚洲精品| 日本人妻中文字幕乱码系列| 两性色午夜视频免费无码| 精品人妻一区二区三区浪潮在线| 西西人体大胆瓣开下部毛茸茸| 亚洲国产制服丝袜先锋| 三上悠亚久久精品| 超碰色偷偷男人的天堂| 中文字幕久久精品一区二区三区| 日本成本人片免费网站| 国产99在线 | 亚洲| 影音先锋中文无码一区|