在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Dihydroorotate dehydrogenase (quinone), mitochondrial (DHODH), partial

Recombinant Human Dihydroorotate dehydrogenase (quinone), mitochondrial (DHODH), partial

  • 中文名稱：
    人DHODH重組蛋白
  • 貨號：
    CSB-YP006852HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人DHODH重組蛋白
  • 貨號：
    CSB-EP006852HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人DHODH重組蛋白
  • 貨號：
    CSB-EP006852HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人DHODH重組蛋白
  • 貨號：
    CSB-BP006852HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人DHODH重組蛋白
  • 貨號：
    CSB-MP006852HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    DHODH
  • Uniprot No.：
  • 別名：
    DHOdehase; Dhodh; Dihydroorotate dehydrogenase (quinone); Dihydroorotate dehydrogenase; Dihydroorotate dehydrogenase mitochondrial; Dihydroorotate oxidase; Human complement of yeast URA1; mitochondrial; POADS; PYRD_HUMAN; URA1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
  • 基因功能參考文獻：
    1. This case with grossly raised plasma DHO represents the first biochemical confirmation of functional DHODH deficiency. DHO was also easily detectable in dried plasma and blood spots. PMID: 27370710
    2. This is the first study to report on conformational changes of the HsDHODH N-terminal microdomain through a combination of CD and DEER spectroscopic techniques PMID: 26086954
    3. Considering that pyrimidine deficiency alone does not induce craniofacial dysmorphism, the DHODH mutations may contribute to the Miller syndrome in part through somehow altered mitochondrial function. PMID: 23216091
    4. Carriage of a six-marker DHODH haplotype was associated with a reduced treatment response (p = 0.008). PMID: 22966891
    5. The G202A and R346W mutation causes deficient protein stability, and the R135C mutation impairs the substrate-induced enzymatic activity, suggesting that impairment of DHODH activity is linked to the Miller syndrome phenotype. PMID: 22967083
    6. biallelic DHODH mutations in four unrelated families with typical clinical features of Miller syndrome. PMID: 22692683
    7. DHODH inhibition led to a marked decrease in melanoma growth both in vitro and in xenograft studies PMID: 21430780
    8. DHODH recessively causes Miller syndrome. PMID: 20220176
    9. required for N-(4-hydroxyphenyl)retinamide-induced reactive oxygen species production and apoptosis of cancer epithelial cells PMID: 20399851
    10. Data confirmed the presence of DHODH mutations in families with Miller syndrome. PMID: 19915526
    11. biophysical analysis of hydrogen bonding pathways in human dihydroorotate dehydrogenase PMID: 17004840
    12. Data provide new insights into the dynamic features of the DHODH reaction and suggest new approaches to the design of inhibitors against DHODH. PMID: 18672895
    13. DHODH polymorphism may be associated with incireased remiaaion in leflunomide treatment in rheumatoid arthritis patients. PMID: 19207032
    14. we report a new association of DHODH A40C polymorphism with leflunomide toxicity in patients with Rheumatoid Arthritis. PMID: 19605743

    顯示更多

    收起更多

  • 相關疾病：
    Postaxial acrofacial dysostosis (POADS)
  • 亞細胞定位：
    Mitochondrion inner membrane; Single-pass membrane protein.
  • 蛋白家族：
    Dihydroorotate dehydrogenase family, Type 2 subfamily
  • 數據庫鏈接：

    HGNC: 2867

    OMIM: 126064

    KEGG: hsa:1723

    STRING: 9606.ENSP00000219240

    UniGene: Hs.654427



主站蜘蛛池模板： 疯狂三人交性欧美| 国产亚洲精品久久久久久| √8天堂资源地址中文在线| 亚洲国产av玩弄放荡人妇| 国产成人精品三级在线影院| 亚洲乱码中文论理电影 | 99久视频只有精品2019| 麻豆av久久av盛宴av| 在线视频观看免费视频18| 国产一精品一av一免费| 亚洲成av人片在线观看| 亚洲精品亚洲人成在线观看| 四川骚妇无套内射舔了更爽| 狠狠色噜噜狠狠狠狠色综合网 | 亚洲综合国产一区二区三区| 国产精品自在自线视频| 宅宅午夜无码一区二区三区| 激情综合婷婷丁香五月蜜桃| 激情久久av一区av二区av三区| 香蕉午夜福利院| 337p日本大胆欧久久| 国产亚洲欧美日韩俺去了| 欧美黑人巨大xxxxx| 熟妇人妻av无码一区二区三区| 国产又黄又刺激又高潮的网站| 国产免费人成在线视频网站| 女人国产香蕉久久精品| 久久人人爽天天玩人人妻精品| 人禽杂交18禁网站免费 | 日本特黄特色aaa大片免费| 亚洲精品国产电影| 亚洲精品偷拍无码不卡av| 亚洲精品久久久久久动漫| 老熟女高潮一区二区三区| 在线日韩日本国产亚洲| 手机看黄av免费网址| 国产成人久久综合第一区| 国产成人无码一区二区在线观看 | 人澡人人澡人人澡欧美| 国产精品免费福利久久| 日韩成av人片在线观看|