在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DHODH Antibody, HRP conjugated

  • 中文名稱:
    DHODH兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA006852LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DHODH Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    DHODH
  • 別名:
    DHOdehase antibody; Dhodh antibody; Dihydroorotate dehydrogenase (quinone) antibody; Dihydroorotate dehydrogenase antibody; Dihydroorotate dehydrogenase mitochondrial antibody; Dihydroorotate oxidase antibody; Human complement of yeast URA1 antibody; mitochondrial antibody; POADS antibody; PYRD_HUMAN antibody; URA1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Dihydroorotate dehydrogenase (quinone), mitochondrial protein (241-395AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
  • 基因功能參考文獻:
    1. This case with grossly raised plasma DHO represents the first biochemical confirmation of functional DHODH deficiency. DHO was also easily detectable in dried plasma and blood spots. PMID: 27370710
    2. This is the first study to report on conformational changes of the HsDHODH N-terminal microdomain through a combination of CD and DEER spectroscopic techniques PMID: 26086954
    3. Considering that pyrimidine deficiency alone does not induce craniofacial dysmorphism, the DHODH mutations may contribute to the Miller syndrome in part through somehow altered mitochondrial function. PMID: 23216091
    4. Carriage of a six-marker DHODH haplotype was associated with a reduced treatment response (p = 0.008). PMID: 22966891
    5. The G202A and R346W mutation causes deficient protein stability, and the R135C mutation impairs the substrate-induced enzymatic activity, suggesting that impairment of DHODH activity is linked to the Miller syndrome phenotype. PMID: 22967083
    6. biallelic DHODH mutations in four unrelated families with typical clinical features of Miller syndrome. PMID: 22692683
    7. DHODH inhibition led to a marked decrease in melanoma growth both in vitro and in xenograft studies PMID: 21430780
    8. DHODH recessively causes Miller syndrome. PMID: 20220176
    9. required for N-(4-hydroxyphenyl)retinamide-induced reactive oxygen species production and apoptosis of cancer epithelial cells PMID: 20399851
    10. Data confirmed the presence of DHODH mutations in families with Miller syndrome. PMID: 19915526
    11. biophysical analysis of hydrogen bonding pathways in human dihydroorotate dehydrogenase PMID: 17004840
    12. Data provide new insights into the dynamic features of the DHODH reaction and suggest new approaches to the design of inhibitors against DHODH. PMID: 18672895
    13. DHODH polymorphism may be associated with incireased remiaaion in leflunomide treatment in rheumatoid arthritis patients. PMID: 19207032
    14. we report a new association of DHODH A40C polymorphism with leflunomide toxicity in patients with Rheumatoid Arthritis. PMID: 19605743

    顯示更多

    收起更多

  • 相關疾病:
    Postaxial acrofacial dysostosis (POADS)
  • 亞細胞定位:
    Mitochondrion inner membrane; Single-pass membrane protein.
  • 蛋白家族:
    Dihydroorotate dehydrogenase family, Type 2 subfamily
  • 數據庫鏈接:

    HGNC: 2867

    OMIM: 126064

    KEGG: hsa:1723

    STRING: 9606.ENSP00000219240

    UniGene: Hs.654427



主站蜘蛛池模板: 亚洲深深色噜噜狠狠网站| 无码国产偷倩在线播放| 曰批免费视频播放免费直播| 国产精品久久久久久免费软件 | 377人体粉嫩噜噜噜| 人妻少妇精品中文字幕av| 亚洲中文字幕婷婷在线| 特级小箩利无码毛片| 国产精品午夜小视频观看| 亚洲字幕av一区二区三区四区| 久久精品国产亚洲a片高清不卡| 久久青草成人综合网站| 国产精品夜夜春夜夜爽久久小说| 嫩草伊人久久精品少妇av| 国产黄a三级三级三级av在线看| 丝袜无码一区二区三区| 无码人妻丝袜在线视频红杏 | 亚洲va在线va天堂va欧美va| 久久精品成人亚洲另类欧美| 亚洲第一区无码专区| 亚洲337少妇裸体艺术| 欧美日本特级婬片视频| 67194熟妇在线观看线路1| 国产激情无码一区二区| 久久亚洲道色综合久久| 137肉体摄影日本裸交| 亚洲一卡二卡三卡四卡| 天天狠天天透天干天干| 国产综合有码无码中文字幕| 亚洲精品久久夜色撩人男男小说| 国产精品美女久久久久久久| 国产高潮抽搐喷水高清| 五月激情婷婷丁香综合基地| 亚洲熟妇丰满多毛xxxx| 精品一区二区三区免费视频| 日本又色又爽又黄的视频免| 久欠精品国国产99国产精2021| 奶头又大又白喷奶水av| 免费无码毛片一区二三区| 夜色福利院在线观看免费| 久久狼人大香伊蕉国产|