在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PLXNB2 Antibody， Biotin conjugated

PLXNB2 Antibody， Biotin conjugated

  • 中文名稱：
    PLXNB2兔多克隆抗體， Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA018223LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PLXNB2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    PLXNB2 antibody; KIAA0315 antibody; Plexin-B2 antibody; MM1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Inhibitor of nuclear factor kappa-B kinase-interacting protein (1458-1673AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Antigen Affinity purified & Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42.
  • 基因功能參考文獻(xiàn)：
    1. Knocking down of PLXNB2 with PLXNB2 siRNA results in repressed ovarian cancer cell proliferation and invasion, and decreased phosphorylation of AKT and ERK1/2 PMID: 30054097
    2. Study shows that plexin-B2 (PLXNB2) is the functional receptor for ANG in endothelial, cancer, neuronal, and normal hematopoietic and leukemic stem and progenitor cells. PMID: 29100074
    3. Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins shows lack of binding specificity. PMID: 29040270
    4. plexin-B2 is a downstream target for Rnd3, which contributes to its cellular function. PMID: 27656111
    5. Plexin-B2 promotes glioma invasion and vascularization PMID: 25762646
    6. In endometrial luminal epithelium, cadherin 6, desmoglein 2 and plexin b2 were surprisingly found in the apical as well as the lateral membrane domain; their knock-down compromised epithelial integrity. PMID: 25237006
    7. High PLEXIN B2 expression is associated with high-grade gliomas. PMID: 24158112
    8. Plexin B2 associates directly with two members of a recently identified family of Dbl homology/pleckstrin homology containing guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and Leukemia-associated Rho GEF (LARG). PMID: 12183458
    9. cleavage by proprotein convertases is a novel regulatory step for semaphorin receptors localized at the cell surface. PMID: 12533544

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Plexin family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 9104

    OMIM: 604293

    KEGG: hsa:23654

    STRING: 9606.ENSP00000352288

    UniGene: Hs.3989



主站蜘蛛池模板： 午夜无码福利伦利理免| 香蕉久久一区二区三区啪啪| 国产乱子伦三级在线播放| 亚洲人成网站18禁止大| 亚洲日韩亚洲另类| 国产小呦泬泬99精品| 99riav国产精品视频| 中文天堂在线资源www| 国产作爱激烈叫床视频| 风韵少妇性饥渴推油按摩视频| 好紧好爽好湿别拔出来视频男男| 精品久久久久久国产潘金莲| 18禁成人黄网站免费观看久久 | 婷婷五月开心亚洲综合在线| 中文字幕久久精品无码| 国产一码二码三码区别| 国内揄拍国产精品人妻门事件| 18禁区美女免费观看网站| 国产精品玩偶在线观看| 性欧美暴力猛交69hd| 午夜性开放午夜性爽爽| 少妇高潮喷水在线观看| 2020久久国产综合精品swag| 天天躁人人躁人人躁狂躁| 精品无码黑人又粗又大又长| 久久久受www免费人成| 92午夜少妇极品福利无码电影| 极品美女扒开粉嫩小泬图片| 国产精品第一国产精品| 久久精品女人的天堂av| 亚洲国产精品无码中文字| 女人扒开屁股爽桶30分钟 | 亚洲中久无码永久在线观看同 | 日本少妇人妻xxxxx18| 在线精品视频一区二区三区| 少妇做爰免费视频网站| 国产精品主播一区二区三区| 99久久精品费精品国产| 巨爆乳无码视频在线观看| 国产亚洲精品久久yy5099| 国产成人综合久久免费|