在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PLXNB2 Antibody

PLXNB2 Antibody

  • 中文名稱：
    PLXNB2兔多克隆抗體
  • 貨號：
    CSB-PA018223GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    PLXNB2 antibody; KIAA0315 antibody; Plexin-B2 antibody; MM1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human PLXNB2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42.
  • 基因功能參考文獻：
    1. Knocking down of PLXNB2 with PLXNB2 siRNA results in repressed ovarian cancer cell proliferation and invasion, and decreased phosphorylation of AKT and ERK1/2 PMID: 30054097
    2. Study shows that plexin-B2 (PLXNB2) is the functional receptor for ANG in endothelial, cancer, neuronal, and normal hematopoietic and leukemic stem and progenitor cells. PMID: 29100074
    3. Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins shows lack of binding specificity. PMID: 29040270
    4. plexin-B2 is a downstream target for Rnd3, which contributes to its cellular function. PMID: 27656111
    5. Plexin-B2 promotes glioma invasion and vascularization PMID: 25762646
    6. In endometrial luminal epithelium, cadherin 6, desmoglein 2 and plexin b2 were surprisingly found in the apical as well as the lateral membrane domain; their knock-down compromised epithelial integrity. PMID: 25237006
    7. High PLEXIN B2 expression is associated with high-grade gliomas. PMID: 24158112
    8. Plexin B2 associates directly with two members of a recently identified family of Dbl homology/pleckstrin homology containing guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and Leukemia-associated Rho GEF (LARG). PMID: 12183458
    9. cleavage by proprotein convertases is a novel regulatory step for semaphorin receptors localized at the cell surface. PMID: 12533544

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Plexin family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9104

    OMIM: 604293

    KEGG: hsa:23654

    STRING: 9606.ENSP00000352288

    UniGene: Hs.3989



主站蜘蛛池模板： 色婷婷亚洲精品综合影院| 男女又色又爽又爽视频| 亚洲综合精品第一页| 九九99精品久久久久久综合| 少妇人妻无码专区视频| 久久成人影院精品777| 日韩无套内射视频6| 中文字幕精品久久久久人妻红杏| 免费无码又爽又刺激软件下载直播 | 亚洲第一极品精品无码| 97se狼狼狼狼狼亚洲网| 中文字幕人妻丝袜乱一区三区 | 国产欧美精品一区二区三区-老狼| 夜夜春亚洲嫩草影院| 日本 精品 高清不卡| 后入内射国产一区二区| 大肉大捧一进一出好爽app| 无码中文字幕av免费放| 超清无码波多野吉衣中文 | 日韩一区二区在线观看视频| 午夜尤物禁止18点击进入| 日韩欧美激情兽交| 人妻在线日韩免费视频| 国产精品自在线拍国产| 国产av影片麻豆精品传媒| 欧美老熟妇乱子| 含紧一点h边做边走动免费视频| 国产免国产免费| 亚洲欧洲日产韩国无码| 性色欲情网站iwww九文堂| 激情综合色五月丁香六月亚洲| 欧美牲交a欧美牲交aⅴ免费下载| 欧美日韩亚洲tv不卡久久| 国产精品人妻一区二区高| 久久精品无码中文字幕| 在线成人a毛片免费播放| 日韩人妻少妇一区二区三区| 久久香蕉国产线看观看精品yw| 久久免费午夜福利院| 亚洲国产精品无码久久秋霞| 免费做a爰片久久毛片a片|