在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PLXNB2 Antibody

PLXNB2 Antibody

  • 中文名稱(chēng)：
    PLXNB2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA347467
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA347467(PLXNB2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    PLXNB2 antibody; KIAA0315 antibody; Plexin-B2 antibody; MM1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human PLXNB2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42.
  • 基因功能參考文獻(xiàn)：
    1. Knocking down of PLXNB2 with PLXNB2 siRNA results in repressed ovarian cancer cell proliferation and invasion, and decreased phosphorylation of AKT and ERK1/2 PMID: 30054097
    2. Study shows that plexin-B2 (PLXNB2) is the functional receptor for ANG in endothelial, cancer, neuronal, and normal hematopoietic and leukemic stem and progenitor cells. PMID: 29100074
    3. Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins shows lack of binding specificity. PMID: 29040270
    4. plexin-B2 is a downstream target for Rnd3, which contributes to its cellular function. PMID: 27656111
    5. Plexin-B2 promotes glioma invasion and vascularization PMID: 25762646
    6. In endometrial luminal epithelium, cadherin 6, desmoglein 2 and plexin b2 were surprisingly found in the apical as well as the lateral membrane domain; their knock-down compromised epithelial integrity. PMID: 25237006
    7. High PLEXIN B2 expression is associated with high-grade gliomas. PMID: 24158112
    8. Plexin B2 associates directly with two members of a recently identified family of Dbl homology/pleckstrin homology containing guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and Leukemia-associated Rho GEF (LARG). PMID: 12183458
    9. cleavage by proprotein convertases is a novel regulatory step for semaphorin receptors localized at the cell surface. PMID: 12533544

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Plexin family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 9104

    OMIM: 604293

    KEGG: hsa:23654

    STRING: 9606.ENSP00000352288

    UniGene: Hs.3989



主站蜘蛛池模板： 女人高潮抽搐潮喷视频开腿| 久久久久噜噜噜亚洲熟女综合 | 国产成人啪精品午夜网站a片免费| 欧美成人片在线观看| 亚洲日本中文字幕天天更新| 国产96色在线 | 国| 色妺妺免费影院| 在线不卡av片免费观看| 水蜜桃av导航| 一本一道人人妻人人妻αv| 国产在线拍偷自揄拍无码| 亚洲中文欧美在线视频| 18禁成人黄网站免费观看久久| 国产成人无码一区二区在线观看| 成人免费的视频| 狠狠做深爱婷婷丁香综合| 国产精品成人观看视频| 国产人妻一区二区三区四区五区六| 久久丫精品国产| 亚洲精品制服丝袜四区| 欧美性猛少妇xxxxx免费| 毛片免费全部播放无码| 欧美性生交xxxxx久久久| 人妻人人澡人人添人人爽人人玩| 久久99热只有频精品8| 国产黑色丝袜在线视频 | 夜夜高潮夜夜爽国产伦精品| 亚洲最大日夜无码中文字幕| 清纯唯美经典一区二区| 精品一区国产vr| 男女啪啪永久免费观看网站| 日韩精品无码一区二区中文字幕 | 国产成人av区一区二区三| 中国少妇内射xxxhd免费| 国产精品久久久久9999小说| 久青草影院在线观看国产| 日韩在线成年视频人网站观看| 色翁荡熄又大又硬又粗又动态图| 毛片tv网站无套内射tv网站| 亚洲手机在线人成网站| 国产欧美性成人精品午夜|