在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PLXNB2 Antibody

PLXNB2 Antibody

  • 中文名稱：
    PLXNB2兔多克隆抗體
  • 貨號：
    CSB-PA124601
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA124601(PLXNB2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA124601(PLXNB2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    PLXNB2 antibody; KIAA0315 antibody; Plexin-B2 antibody; MM1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human PLXNB2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42.
  • 基因功能參考文獻：
    1. Knocking down of PLXNB2 with PLXNB2 siRNA results in repressed ovarian cancer cell proliferation and invasion, and decreased phosphorylation of AKT and ERK1/2 PMID: 30054097
    2. Study shows that plexin-B2 (PLXNB2) is the functional receptor for ANG in endothelial, cancer, neuronal, and normal hematopoietic and leukemic stem and progenitor cells. PMID: 29100074
    3. Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins shows lack of binding specificity. PMID: 29040270
    4. plexin-B2 is a downstream target for Rnd3, which contributes to its cellular function. PMID: 27656111
    5. Plexin-B2 promotes glioma invasion and vascularization PMID: 25762646
    6. In endometrial luminal epithelium, cadherin 6, desmoglein 2 and plexin b2 were surprisingly found in the apical as well as the lateral membrane domain; their knock-down compromised epithelial integrity. PMID: 25237006
    7. High PLEXIN B2 expression is associated with high-grade gliomas. PMID: 24158112
    8. Plexin B2 associates directly with two members of a recently identified family of Dbl homology/pleckstrin homology containing guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and Leukemia-associated Rho GEF (LARG). PMID: 12183458
    9. cleavage by proprotein convertases is a novel regulatory step for semaphorin receptors localized at the cell surface. PMID: 12533544

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Plexin family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9104

    OMIM: 604293

    KEGG: hsa:23654

    STRING: 9606.ENSP00000352288

    UniGene: Hs.3989



主站蜘蛛池模板： 精品国产av一区二区果冻传媒| 亚洲中文字幕无码日韩| 国产精品丝袜肉丝出水| 国产又爽又黄无码无遮挡在线观看 | 亚洲第一天堂无码专区| 丰满无码人妻热妇无码区| 久久国产av影片| 色噜噜狠狠狠狠色综合久| 亚洲人成在线观看| 精品无码av不卡一区二区三区| 久久国产精品萌白酱免费| 亚洲图片校园另激情类小说| 国产精品青草久久福利不卡| 韩国日本三级在线观看| 人妻久久久一区二区三区| 亚洲综合在线另类色区奇米| 色综合久久久久综合99| 2021久久超碰国产精品最新| 免费人成视频19674不收费| 超清中文乱码字幕在线观看| 嫖妓丰满肥熟妇在线精品| 午夜福利国产成人a∨在线观看| 岛国在线无码高清视频| 亚洲精品国产一区黑色丝袜| 国语精品一区二区三区| 中文字幕一二三区波多野结衣 | 99久久99视频只有精品| 国产av一区二区三区日韩| 大战熟女丰满人妻av| 亚洲已满18点击进入在线观看| 中文字幕无线码成人免费看| 在线成人精品国产区免费| 中文字幕在线亚洲精品| 特级欧美插插插插插bbbbb| 少妇精品揄拍高潮少妇| 99久热re在线精品99re8热视频 | 处破痛哭a√18成年片免费| 亚洲日韩色在线影院性色| 中文字幕资源网| 中文字幕乱码亚洲精品一区 | 久久国产精品精品国产色婷婷|