在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PLXNB2 Antibody， Biotin conjugated

PLXNB2 Antibody， Biotin conjugated

  • 中文名稱：
    PLXNB2兔多克隆抗體， Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA018223LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PLXNB2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    PLXNB2 antibody; KIAA0315 antibody; Plexin-B2 antibody; MM1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Inhibitor of nuclear factor kappa-B kinase-interacting protein (1458-1673AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Antigen Affinity purified & Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42.
  • 基因功能參考文獻(xiàn)：
    1. Knocking down of PLXNB2 with PLXNB2 siRNA results in repressed ovarian cancer cell proliferation and invasion, and decreased phosphorylation of AKT and ERK1/2 PMID: 30054097
    2. Study shows that plexin-B2 (PLXNB2) is the functional receptor for ANG in endothelial, cancer, neuronal, and normal hematopoietic and leukemic stem and progenitor cells. PMID: 29100074
    3. Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins shows lack of binding specificity. PMID: 29040270
    4. plexin-B2 is a downstream target for Rnd3, which contributes to its cellular function. PMID: 27656111
    5. Plexin-B2 promotes glioma invasion and vascularization PMID: 25762646
    6. In endometrial luminal epithelium, cadherin 6, desmoglein 2 and plexin b2 were surprisingly found in the apical as well as the lateral membrane domain; their knock-down compromised epithelial integrity. PMID: 25237006
    7. High PLEXIN B2 expression is associated with high-grade gliomas. PMID: 24158112
    8. Plexin B2 associates directly with two members of a recently identified family of Dbl homology/pleckstrin homology containing guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and Leukemia-associated Rho GEF (LARG). PMID: 12183458
    9. cleavage by proprotein convertases is a novel regulatory step for semaphorin receptors localized at the cell surface. PMID: 12533544

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Plexin family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 9104

    OMIM: 604293

    KEGG: hsa:23654

    STRING: 9606.ENSP00000352288

    UniGene: Hs.3989



主站蜘蛛池模板： 国产麻豆成人传媒免费观看| 亚洲综合日韩av无码毛片| 日韩aⅴ人妻无码一区二区| 亚洲国产长腿丝袜av天堂| 精品无码久久久久国产手机版| 午夜性色福利在线视频福利| 天天爽夜夜爽视频精品| 欧美人与动牲猛交a欧美精品| 欧美性猛交xxxx乱大交极品| 午夜福利啪啪无遮挡免费| 中文午夜人妻无码看片| 国产又黄又大又粗的视频| 天堂中文在线资源| 成人片黄网站a毛片免费观看 | 男女性色大片免费网站| 国自产拍偷拍精品啪啪模特 | 人妻丰满熟妇av无码区| 国产亚洲精品久久久久四川人| 国产婷婷成人久久av免费高清| 欧美肥婆性猛交xxxx| 精品卡1卡2卡三卡免费网站| 国产精品 视频一区 二区三区 | 777奇米四色成人影视色区| 亚洲精品无码伊人久久| 中文字幕有码无码人妻av蜜桃| 综合色区亚洲熟妇另类| 国模国产精品嫩模大尺度视频| 2020精品国产自在现线官网 | 国产亚洲日韩在线a不卡| 中文字幕av无码一区二区三区| 国产精品丝袜久久久久久不卡| 中文字幕在线精品视频入口一区| 一本加勒比hezyo无码专区| 精品夜夜爽欧美毛片视频| 最新版天堂资源中文官网| 亚洲高清一区二区三区不卡 | 丰满少妇人妻无码| 摸丰满大乳奶水www免费| 无码av动漫精品一区二区免费| 国产成人精品午夜福利不卡| 色爱无码av综合区|