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TRIM72

TRIM72,全稱為Tripartite Motif Containing 72,是一種肌肉特異性蛋白,也被稱為Mitsugumin-53或Mg53。它在細胞膜修復中扮演重要角色,能夠修復受損的細胞膜,并參與細胞自噬過程。TRIM72與多種信號通路有關(guān),如胰島素受體信號通路和肌管分化的負調(diào)控。此外,TRIM72的異常與某些疾病相關(guān),如肌萎縮側(cè)索硬化(漸凍癥)。近年來,針對TRIM72的藥物研發(fā)取得進展,例如全球首款針對漸凍癥的基因治療藥物SNUG01,它通過遞送工程化TRIM72基因來修復受損的神經(jīng)元,為漸凍癥患者帶來了新的治療希望。

熱銷產(chǎn)品

Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial (CSB-EP744394HU)

驗證數(shù)據(jù)

CSB-EP744394HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TRIM72 Antibody (CSB-PA080146)

驗證數(shù)據(jù)

CSB-PA080146

Immunohistochemical analysis of paraffin-embedded Mouse PancreasTissue using TRIM72 Polyclonal Antibody.

CSB-PA080146

Western blot analysis of Mouse skeletal muscle using TRIM72 Polyclonal Antibody.

Human Tripartite motif-containing protein 72(TRIM72) ELISA kit (CSB-EL024511HU)

驗證數(shù)據(jù)

CSB-EL024511HU 標準曲線

貨號:CSB-EL024511HU

規(guī)格:96T/48T

靈敏度:6.25 pg/mL

檢測范圍:25 pg/mL-1600 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

TRIM72 Antibodies

TRIM72 for Homo sapiens (Human)

TRIM72 Proteins

TRIM72 Proteins for Homo sapiens (Human)

TRIM72 ELISA Kit

TRIM72 ELISA Kit for Homo sapiens (Human)