在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial

Unavailable
  • 中文名稱:
    人TRIM72重組蛋白
  • 貨號:
    CSB-MP744394HU
  • 規格:
    ¥2640
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    LOC493829; Mg53; Mitsugumin-53; TRI72_HUMAN; trim72; Tripartite motif containing 72; Tripartite motif containing protein 72 ; Tripartite motif-containing protein 72
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    Mammalian cell
  • 分子量:
    32.5 kDa
  • 表達區域:
    1-269aa
  • 氨基酸序列
    MSAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTNLQLARLVEGLAQVPQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLAALEGSLDREAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIIS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal Flag-Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.
  • 基因功能參考文獻:
    1. serum TRIM72 may be a potential biomarker for the diagnosis and the prognosis of colon cancer. PMID: 29806630
    2. MG53 is an effective biomarker of myocardial injury and dysfunction in murine hearts. However, MG53 is not expressed in human heart and therefore does not hold utility as a clinical biomarker of myocardial injury PMID: 26790476
    3. MG53 is a facilitator of rapid injury repair, a mediator of cell migration, and a modulator of myofibroblast differentiation during wound healing PMID: 26306047
    4. Zn(2+) interacts with MG53 in protection against injury to the cell membrane PMID: 25869134
    5. MG53 induces FAK ubiquitination with the aid of UBE2H during skeletal myogenesis. PMID: 24344130
    6. MG53/TRIM72 protein can be directly applied as a therapeutic agent to increase membrane repair capacity of many cell types. PMID: 23699904
    7. data reveal NM-IIA as a key cytoskeleton motor protein that facilitates vesicle trafficking during MG53-mediated cell membrane repair PMID: 22253476
    8. membrane-delimited interaction between MG53 and PTRF contributes to initiation of cell membrane repair PMID: 21343302
    9. MG53, annexin A1, and dysferlin localize to the t-tubule network and show enriched labeling at longitudinal tubules of the t-system in overstretch PMID: 21412170
    10. Crystal structure of PRY-SPRY domain of human TRIM72. PMID: 19967786
    11. Observational study and meta-analysis of gene-disease association. (HuGE Navigator) PMID: 19129174

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane, sarcolemma. Cytoplasmic vesicle membrane.
  • 蛋白家族:
    TRIM/RBCC family
  • 數據庫鏈接:

    HGNC: 32671

    OMIM: 613288

    KEGG: hsa:493829

    STRING: 9606.ENSP00000312675

    UniGene: Hs.661859



主站蜘蛛池模板: 99久久国产宗和精品1上映| 欧美人和黑人牲交网站上线| 国产精品后入内射日本在线观看| 国产精品-区区久久久狼| 亚洲国产精品一区二区动图| 久久不见久久见免费视频1′| 中文字幕精品久久久久人妻| 97精品一区二区视频在线观看| 国产成人欧美亚洲日韩电影| 国产高清av喷水白丝护士| 国产精品日本一区二区不卡视频| 老熟妇性老熟妇性色| 欧美黑人又大又粗xxxxx| 久国产精品人妻aⅴ| 精品国产av最大网站| 丰满少妇做爰视频爽爽和| 精品熟女日韩中文十区| 国产精品成人a区在线观看| 亚洲欧洲自拍拍偷精品网 | 最激烈的床震娇喘视频出水| 国产a∨精品一区二区三区不卡| av午夜久久蜜桃传媒软件| 草草久久97超级碰碰碰| 亚洲.欧美.在线视频| 鲁大师在线视频播放免费观看| 日本人妻人人人澡人人爽| 国产永久免费观看的黄网站| 国产亚洲精品久久yy50| 欧美激情日韩精品久久久| 亚洲精品夜夜夜妓女网| 久久久橹橹橹久久久久| 成人欧美一区二区三区的电影| 国产欧美二区综合| 成人无码av网站在线观看| 中文无码久久精品| 国产精品多人p群无码| 美女粉嫩饱满的一线天mp4| 国产在线精品一区在线观看| 俺也来俺也去俺也射| 精品午夜福利在线视在亚洲 | 国产午夜手机精彩视频|