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OSM

OSM(Oncostatin M)是一種細胞因子蛋白。它是白細胞介素6(Interleukin-6,IL-6)家族中的成員之一,其結構是一種由單一多肽鏈組成的蛋白質,它與細胞表面上的受體結合,觸發下游信號轉導途徑。 OSM在免疫調節、細胞增殖、分化和炎癥等生理過程中發揮著重要作用。參與調控多種細胞類型的增殖和分化,包括肝細胞、胚胎干細胞、神經細胞等。在炎癥性疾病中,OSM可以調節免疫細胞的活化和炎癥反應。在腫瘤發展中,OSM可能促進腫瘤細胞的增殖和侵襲。 由于OSM在生理和病理過程中的重要作用,對其的研究對于理解免疫調節、炎癥反應和腫瘤生物學等方面具有重要意義。同時,OSM也被認為是潛在的治療靶點,針對OSM和其受體的治療方法可能有助于調節疾病過程和發展新的治療策略。

更多相關閱讀:抑瘤素M (OSM): 白介素IL-6細胞因子家族成員,腫瘤、骨代謝、慢性炎癥性等疾病的潛力靶點?

熱銷產品

OSM Recombinant Monoclonal Antibody CSB-RA017260MA1HU

驗證數據

ELISA
CSB-RA017260MA1HU ELISA

The Binding Activity of Human OSM with Anti-OSM Recombinant Antibody

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human OSM (CSB-MP017260HU1) at 2 μg/mL can bind Anti-OSM recombinant antibody, the EC50 is 3.048-3.860 ng/mL

Recombinant Human Oncostatin-M(OSM),partial (Active) CSB-MP017260HU1

驗證數據

SDS
CSB-MP017260HU1 SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
CSB-MP017260HU1 ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human OSM at 2μg/mL can bind Anti-OSM recombinant antibody (CSB-RA017260MA1HU),the EC50 is 3.048-3.860 ng/mL.

OSM Antibodies

OSM for Homo sapiens (Human)

OSM for Rattus norvegicus (Rat)

OSM Proteins

OSM Proteins for Homo sapiens (Human)

OSM Proteins for Bos taurus (Bovine)

OSM Proteins for Mus musculus (Mouse)

OSM Proteins for Rattus norvegicus (Rat)

OSM ELISA Kit

OSM ELISA Kit for Homo sapiens (Human)

OSM ELISA Kit for Mus musculus (Mouse)

OSM ELISA Kit for Rattus norvegicus (Rat)