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  4. Osm Antibody, HRP conjugated

Osm Antibody, HRP conjugated

Rare Species
  • 中文名稱：
    Osm兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA723970LB01RA
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Rattus norvegicus (Rat) Osm Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Osm antibody; Oncostatin-M antibody; OSM antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Rat
  • 免疫原：
    Recombinant Rat Oncostatin-M protein (26-207AA)
  • 免疫原種屬：
    Rattus norvegicus (Rat)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
  • 基因功能參考文獻：
    1. OSM is a key mediator for inducing differentiation of OC15-5 cells into hepatocytes PMID: 15743783
    2. In the immortalized mouse and primary cultured proliferative rat hepatocytes, treatment with OSM markedly increased mRNA and protein of claudin-2 together with formation of developed networks of TJ strands. PMID: 17434483
    3. OSM may not only play a role in the regulation of Sertoli cell proliferation and the initiation of spermatogenesis but may also play a role in the regulation of Leydig cell progenitor formation. PMID: 17996055
    4. Results indicate that osteosarcoma cells stably producing OSM do not develop resistance to this cytokine and thus could be a valuable new tool to study the anti-cancer effect of OSM in vivo. PMID: 19168167
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    LIF/OSM family
  • 組織特異性：
    Widely expressed. Expressed at higher levels in liver, skin and spleen.
  • 數據庫鏈接：


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