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Osm Antibody, FITC conjugated

Rare Species
  • 中文名稱:
    Osm兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào):
    CSB-PA723970LC01RA
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Rattus norvegicus (Rat) Osm Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Osm antibody; Oncostatin-M antibody; OSM antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Rat
  • 免疫原:
    Recombinant Rat Oncostatin-M protein (26-207AA)
  • 免疫原種屬:
    Rattus norvegicus (Rat)
  • 標(biāo)記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Growth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
  • 基因功能參考文獻(xiàn):
    1. OSM is a key mediator for inducing differentiation of OC15-5 cells into hepatocytes PMID: 15743783
    2. In the immortalized mouse and primary cultured proliferative rat hepatocytes, treatment with OSM markedly increased mRNA and protein of claudin-2 together with formation of developed networks of TJ strands. PMID: 17434483
    3. OSM may not only play a role in the regulation of Sertoli cell proliferation and the initiation of spermatogenesis but may also play a role in the regulation of Leydig cell progenitor formation. PMID: 17996055
    4. Results indicate that osteosarcoma cells stably producing OSM do not develop resistance to this cytokine and thus could be a valuable new tool to study the anti-cancer effect of OSM in vivo. PMID: 19168167
  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    LIF/OSM family
  • 組織特異性:
    Widely expressed. Expressed at higher levels in liver, skin and spleen.
  • 數(shù)據(jù)庫鏈接:


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