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FLCN

FLCN,即卵泡素,別名BHD、FLCL、DENND8B。FLCN是一種腫瘤抑制因子,可能通過(guò)AMPK和mTOR信號(hào)通路參與能量和/或營(yíng)養(yǎng)感應(yīng),調(diào)節(jié)RPS6KB1的磷酸化。FLCN涉及多種細(xì)胞途徑,包括膜運(yùn)輸、能量和營(yíng)養(yǎng)穩(wěn)態(tài)以及溶酶體生物發(fā)生,通過(guò)調(diào)節(jié)各種代謝途徑,包括線(xiàn)粒體的氧化代謝,維持細(xì)胞穩(wěn)態(tài)。FLCN的突變與Birt-Hogg-Dubé綜合征(BHD綜合征)有關(guān),這是一種常染色體顯性遺傳病,主要臨床表現(xiàn)為毛囊錯(cuò)構(gòu)瘤、腎囊腫和腎腫瘤等。

熱銷(xiāo)產(chǎn)品

FLCN Antibody (CSB-PA549292)

驗(yàn)證數(shù)據(jù)

CSB-PA549292

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA549292(FLCN Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

CSB-PA549292

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA549292(FLCN Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

Human Folliculin(FLCN) ELISA kit (CSB-EL008711HU)

驗(yàn)證數(shù)據(jù)

CSB-EL008711HU 標(biāo)準(zhǔn)曲線(xiàn)

貨號(hào):CSB-EL008711HU

規(guī)格:96T/48T

靈敏度:3.9 pg/mL

檢測(cè)范圍:15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

FLCN Antibodies

FLCN for Homo sapiens (Human)

FLCN Proteins

FLCN Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

FLCN Proteins for Rattus norvegicus (Rat)

FLCN Proteins for Homo sapiens (Human)

FLCN Proteins for Mus musculus (Mouse)

FLCN Proteins for Bos taurus (Bovine)

FLCN ELISA Kit

FLCN ELISA Kit for Homo sapiens (Human)