在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human L-xylulose reductase (DCXR)

  • 中文名稱:
    Recombinant Human L-xylulose reductase(DCXR)
  • 品名簡稱:
    Recombinant Human DCXR protein
  • 貨號:
    CSB-EP772022HU
  • 說明書:
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    DCXR
  • Uniprot No.:
  • 別名:
    Carbonyl reductase 2; Carbonyl reductase II; DCR; Dcxr; DCXR_HUMAN; Dicarbonyl and L xylulose reductase; Dicarbonyl L xylulose reductase; Dicarbonyl/ L xylulose reductase; Dicarbonyl/L-xylulose reductase; HCR2; HCRII; Human carbonyl reductase 2; kiDCR; Kidney dicarbonyl reductase; L xylulose reductase; L-xylulose reductase; P34H; PNTSU; SDR20C1; Short chain dehydrogenase/reductase family 20C member 1; Sperm surface protein P34H; XR
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    52.9kDa
  • 表達區域:
    1-244aa
  • 氨基酸序列
    MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
  • 基因功能參考文獻:
    1. Ureaplasma urealyticum infection may affect the level of P34H protein expression on spermatozoa PMID: 28012250
    2. identification of DCXR as an enzyme activity mediating chemical redox cycling suggests that it may be important in generating cytotoxic reactive oxygen species in the lung PMID: 28595002
    3. Low expression of DCXR is associated with hepatocellular carcinoma. PMID: 27658779
    4. EGCG is a potential inhibitor to human DCXR. PMID: 23661708
    5. combined frequency of the two mutant DCXR alleles in 1,067 Ashkenazi Jewish controls was 0.0173, suggesting a pentosuria frequency of approximately one in 3,300 in this population PMID: 22042873
    6. highly expressed in kidney and liver PMID: 11882650
    7. crystallization and preliminary crystallographic analysis PMID: 12136162
    8. structure of the tetrameric form of human L-Xylulose reductase PMID: 15906319
    9. Our results demonstrate that the proportion of positive P34H cases that produced embryos in vitro clearly differs from cases with undetectable levels of P34H (P<.001). PMID: 16616743
    10. These results suggested that altered HCR2 expression might play roles in the carcinogenesis and progression of hepatocellular carcinoma. PMID: 16847567
    11. A significant proportion of men investigated for male infertility may be epididymal protein P34H deficient. PMID: 17434498
    12. Decreased membranous expression of DCXR with altered subcellular localization appears to be associated with malignant progression of melanocytic lesions in human skin. PMID: 17576332
    13. DCXR trranfected into mice may function in the removal of renal alpha-dicarbonyl compounds under oxidative circumstances, but it is not sufficient to suppress acute renal fibrosis. PMID: 18079483
    14. DCXR overexpression has the potential to be an additional useful biomarker for prostate cancer. PMID: 18086765
    15. The action of human XR may be regulated by cellular redox conditions through reversible disulfide-bond formation and by S-cysteinylation. PMID: 19337691

    顯示更多

    收起更多

  • 相關疾病:
    Pentosuria (PNTSU)
  • 亞細胞定位:
    Membrane; Peripheral membrane protein.
  • 蛋白家族:
    Short-chain dehydrogenases/reductases (SDR) family
  • 組織特異性:
    Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
  • 數據庫鏈接:

    HGNC: 18985

    OMIM: 260800

    KEGG: hsa:51181

    STRING: 9606.ENSP00000303356

    UniGene: Hs.9857



主站蜘蛛池模板: 免费国偷自产拍精品视频| 暖暖的在线观看日本社区| 免费无码av片在线观看国产| 久热中文字幕无码视频| 人妻插b视频一区二区三区| 妺妺窝人体色www在线观看 | 亚洲免费观看在线视频| 97人妻人人做人碰人人爽| 亚洲色在线v中文字幕| 久久人人97超碰超国产| 欧美成人精品一区二区三区色欲 | 一本丁香综合久久久久不卡网站| 碰超免费人妻中文字幕| 国产成人一区二区三区免费视频| 国产成人无码av一区二区| 亚洲综合色成在线播放| 波多野结衣网站| 久久精品国产第一区二区三区| 风韵丰满熟妇啪啪区老老熟女百度 | 国产成人精品日本亚洲一区| 国产无遮挡又黄又爽动态图| 农村老熟妇乱子伦视频| 亚洲精品美女久久7777777| 国产精品无码专区av在线播放| 麻豆视传媒精品av| 欧美伊人色综合久久天天| 秋霞影院午夜伦a片欧美| 亚洲精品国产电影| 国产欧美另类精品久久久| 青青草国产免费久久久下载| 无码人妻丰满熟妇奶水区码| 亚洲 欧美 国产 日韩 精品| 国产成人a人亚洲精品无码 | 999久久久免费精品国产| 18禁免费观看网站| 欲求不满邻居的爆乳在线播放| 精品日韩亚洲欧美高清a| 国产精品无码aⅴ嫩草| 福利视频在线播放| 老汉色老汉首页a亚洲| 国产精品无码dvd在线观看|