在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DCXR Antibody

DCXR Antibody

  • 中文名稱：
    DCXR兔多克隆抗體
  • 貨號：
    CSB-PA772022ESR1HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: DCXR antibody at 2.93μg/ml
      Lane 1: Mouse gonadal tissue
      Lane 2: HepG2 whole cell lysate
      Lane 3: A431 whole cell lysate
      Lane 4: MCF-7 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 26 kDa
      Observed band size: 26 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA772022ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA772022ESR1HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) DCXR Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DCXR
  • 別名：
    Carbonyl reductase 2 antibody; Carbonyl reductase II antibody; DCR antibody; Dcxr antibody; DCXR_HUMAN antibody; Dicarbonyl and L xylulose reductase antibody; Dicarbonyl L xylulose reductase antibody; Dicarbonyl/ L xylulose reductase antibody; Dicarbonyl/L-xylulose reductase antibody; HCR2 antibody; HCRII antibody; Human carbonyl reductase 2 antibody; kiDCR antibody; Kidney dicarbonyl reductase antibody; L xylulose reductase antibody; L-xylulose reductase antibody; P34H antibody; PNTSU antibody; SDR20C1 antibody; Short chain dehydrogenase/reductase family 20C member 1 antibody; Sperm surface protein P34H antibody; XR antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human L-xylulose reductase protein (1-244AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
  • 基因功能參考文獻：
    1. Ureaplasma urealyticum infection may affect the level of P34H protein expression on spermatozoa PMID: 28012250
    2. identification of DCXR as an enzyme activity mediating chemical redox cycling suggests that it may be important in generating cytotoxic reactive oxygen species in the lung PMID: 28595002
    3. Low expression of DCXR is associated with hepatocellular carcinoma. PMID: 27658779
    4. EGCG is a potential inhibitor to human DCXR. PMID: 23661708
    5. combined frequency of the two mutant DCXR alleles in 1,067 Ashkenazi Jewish controls was 0.0173, suggesting a pentosuria frequency of approximately one in 3,300 in this population PMID: 22042873
    6. highly expressed in kidney and liver PMID: 11882650
    7. crystallization and preliminary crystallographic analysis PMID: 12136162
    8. structure of the tetrameric form of human L-Xylulose reductase PMID: 15906319
    9. Our results demonstrate that the proportion of positive P34H cases that produced embryos in vitro clearly differs from cases with undetectable levels of P34H (P<.001). PMID: 16616743
    10. These results suggested that altered HCR2 expression might play roles in the carcinogenesis and progression of hepatocellular carcinoma. PMID: 16847567
    11. A significant proportion of men investigated for male infertility may be epididymal protein P34H deficient. PMID: 17434498
    12. Decreased membranous expression of DCXR with altered subcellular localization appears to be associated with malignant progression of melanocytic lesions in human skin. PMID: 17576332
    13. DCXR trranfected into mice may function in the removal of renal alpha-dicarbonyl compounds under oxidative circumstances, but it is not sufficient to suppress acute renal fibrosis. PMID: 18079483
    14. DCXR overexpression has the potential to be an additional useful biomarker for prostate cancer. PMID: 18086765
    15. The action of human XR may be regulated by cellular redox conditions through reversible disulfide-bond formation and by S-cysteinylation. PMID: 19337691

    顯示更多

    收起更多

  • 相關疾病：
    Pentosuria (PNTSU)
  • 亞細胞定位：
    Membrane; Peripheral membrane protein.
  • 蛋白家族：
    Short-chain dehydrogenases/reductases (SDR) family
  • 組織特異性：
    Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
  • 數據庫鏈接：

    HGNC: 18985

    OMIM: 260800

    KEGG: hsa:51181

    STRING: 9606.ENSP00000303356

    UniGene: Hs.9857



主站蜘蛛池模板： 亚洲老妇色熟女老太| 欧美精品1卡二卡三卡四卡| 一本色道久久综合狠狠躁篇| 一中文字幕日产乱码va| 粉嫩小泬无遮挡久久久久久| 全黄性性激高免费视频| 护士的小嫩嫩好紧好爽| 天堂最新版资源网| 亚洲不卡1卡2卡三卡入口| 中文字幕人妻丝袜乱一区三区| www国产无套内射com| 香港三级韩国三级日本三级| 成人影院yy111111在线| 大帝a∨无码视频在线播放| 女人夜夜春精品a片| 久久人搡人人玩人妻精品首页| 国产成人精品.视频| 成人av久久一区二区三区| 国产成人午夜福利免费无码r| 亚洲国产欧美在线人成app | 国产suv精品一区二区69| 国产手机在线精品| 午夜亚洲www湿好大| 国产网曝门亚洲综合在线| 国产欧美va天堂在线观看视频| 亚洲大尺度无码无码专线一区| 亚洲成a人片77777国产| yy111111少妇影院无码| 无码人妻精品一区二区蜜桃色欲 | 亚洲大码熟女在线观看| 国产成人av 综合 亚洲| 污污污www精品国产网站| 国产精品久久久久蜜臀| 精品一区二区三区影院在线午夜| 久久国产色av免费观看| 女人高潮流白浆视频| 亚洲中文久久精品无码照片| 国产午夜成人无码免费| 亚洲精品久久久久午夜福禁果tⅴ| 日本妇人成熟免费| 无码少妇一区二区浪潮免费|