在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DCXR Antibody

DCXR Antibody

  • 中文名稱：
    DCXR兔多克隆抗體
  • 貨號：
    CSB-PA772022ESR1HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: DCXR antibody at 2.93μg/ml
      Lane 1: Mouse gonadal tissue
      Lane 2: HepG2 whole cell lysate
      Lane 3: A431 whole cell lysate
      Lane 4: MCF-7 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 26 kDa
      Observed band size: 26 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA772022ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA772022ESR1HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) DCXR Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DCXR
  • 別名：
    Carbonyl reductase 2 antibody; Carbonyl reductase II antibody; DCR antibody; Dcxr antibody; DCXR_HUMAN antibody; Dicarbonyl and L xylulose reductase antibody; Dicarbonyl L xylulose reductase antibody; Dicarbonyl/ L xylulose reductase antibody; Dicarbonyl/L-xylulose reductase antibody; HCR2 antibody; HCRII antibody; Human carbonyl reductase 2 antibody; kiDCR antibody; Kidney dicarbonyl reductase antibody; L xylulose reductase antibody; L-xylulose reductase antibody; P34H antibody; PNTSU antibody; SDR20C1 antibody; Short chain dehydrogenase/reductase family 20C member 1 antibody; Sperm surface protein P34H antibody; XR antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human L-xylulose reductase protein (1-244AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
  • 基因功能參考文獻：
    1. Ureaplasma urealyticum infection may affect the level of P34H protein expression on spermatozoa PMID: 28012250
    2. identification of DCXR as an enzyme activity mediating chemical redox cycling suggests that it may be important in generating cytotoxic reactive oxygen species in the lung PMID: 28595002
    3. Low expression of DCXR is associated with hepatocellular carcinoma. PMID: 27658779
    4. EGCG is a potential inhibitor to human DCXR. PMID: 23661708
    5. combined frequency of the two mutant DCXR alleles in 1,067 Ashkenazi Jewish controls was 0.0173, suggesting a pentosuria frequency of approximately one in 3,300 in this population PMID: 22042873
    6. highly expressed in kidney and liver PMID: 11882650
    7. crystallization and preliminary crystallographic analysis PMID: 12136162
    8. structure of the tetrameric form of human L-Xylulose reductase PMID: 15906319
    9. Our results demonstrate that the proportion of positive P34H cases that produced embryos in vitro clearly differs from cases with undetectable levels of P34H (P<.001). PMID: 16616743
    10. These results suggested that altered HCR2 expression might play roles in the carcinogenesis and progression of hepatocellular carcinoma. PMID: 16847567
    11. A significant proportion of men investigated for male infertility may be epididymal protein P34H deficient. PMID: 17434498
    12. Decreased membranous expression of DCXR with altered subcellular localization appears to be associated with malignant progression of melanocytic lesions in human skin. PMID: 17576332
    13. DCXR trranfected into mice may function in the removal of renal alpha-dicarbonyl compounds under oxidative circumstances, but it is not sufficient to suppress acute renal fibrosis. PMID: 18079483
    14. DCXR overexpression has the potential to be an additional useful biomarker for prostate cancer. PMID: 18086765
    15. The action of human XR may be regulated by cellular redox conditions through reversible disulfide-bond formation and by S-cysteinylation. PMID: 19337691

    顯示更多

    收起更多

  • 相關疾病：
    Pentosuria (PNTSU)
  • 亞細胞定位：
    Membrane; Peripheral membrane protein.
  • 蛋白家族：
    Short-chain dehydrogenases/reductases (SDR) family
  • 組織特異性：
    Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
  • 數據庫鏈接：

    HGNC: 18985

    OMIM: 260800

    KEGG: hsa:51181

    STRING: 9606.ENSP00000303356

    UniGene: Hs.9857



主站蜘蛛池模板： 婷婷射精av这里只有精品| 婷婷五月综合激情中文字幕| 中文字幕卡二和卡三的视频| 国产裸体xxxx视频在线播放| 久青草国产97香蕉在线视频| 欧美18videosex性欧美黑吊| 夜夜躁狠狠躁日日躁| 国产一区二区三区四区五区加勒比 | 亚洲学生妹高清av| 国产无遮挡aaa片爽爽| 无码欧精品亚洲日韩一区| 亚洲这里只有久热精品伊人| 成人亚洲欧美日韩在线观看| 成人无遮挡18禁免费视频| 亚洲色无码播放| 午夜成人理论无码电影在线播放| 久久精品中文字幕无码 | 久久国产人妻一区二区| 久久国产精品波多野结衣av| 国产无遮挡又黄又爽又色| 国产欧美另类久久久精品图片| 人人莫人人擦人人看| 少妇又紧又深又湿又爽视频| 4hu四虎永久在线观看| 日韩精品无码一区二区忘忧草| 日本无码一区二区三区不卡免费| 日韩aⅴ人妻无码一区二区| 精品国产三级在线观看| 中文乱码人妻系列一区二区| 国产精品无码2021在线观看 | 粉嫩小泬无遮挡久久久久久| 亚洲va欧美va天堂v国产综合| 日韩精品无码专区免费视频| 亚洲日韩看片无码超清| 欧美交换国产一区内射| 久久久久国产精品人妻| 欧美制服丝袜人妻另类| 成人乱码一区二区三区四区| 狠狠噜天天噜日日噜| 亚洲人成色4444在线观看| 免费的av网站在线观看国产精品|