在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HIST1H1E (Ab-63) Antibody

  • 中文名稱:
    HIST1H1E (Ab-63)兔多克隆抗體
  • 貨號:
    CSB-PA010380PA63ncrHU
  • 規格:
    ¥660
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA010380PA63ncrHU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HIST1H1E
  • 別名:
    H1 histone family member 4 antibody; H1.4 antibody; H14_HUMAN antibody; H1E antibody; H1F4 antibody; Hist1h1e antibody; Histone 1 H1e antibody; Histone cluster 1 H1e antibody; Histone H1 antibody; Histone H1.4 antibody; Histone H1B antibody; MGC116819 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence around site of Lys (63) derived from Human Histone H1.4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻:
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關疾病:
    Rahman syndrome (RMNS)
  • 亞細胞定位:
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族:
    Histone H1/H5 family
  • 數據庫鏈接:

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板: 国产亚洲精品久久久久久彩霞| 亚洲熟妇色xxxxx欧美老妇y | 最新精品国偷自产在线美女足| 精品国产污污免费网站入口| 国产sm调教折磨视频| 中文字幕丰满孑伦无码精品| 国产成人亚洲精品另类动态| 亚洲一区在线日韩在线尤物| 日韩久久久久久中文人妻| 性色av免费网站| 中文在线√天堂| 国产精品一区波多野结衣| 一区二三区国产好的精华液o9| 亚洲一卡2卡3卡4卡5卡乱码观看| 无码人妻丝袜在线视频| 少妇熟女视频一区二区三区| 中文字幕无码av正片| 国产午夜亚洲精品国产成人 | 欧美一区二区三区| 国语国产精精品国产国语清晰对话| 亚洲欧美韩国综合色| 三级理论中文字幕在线播放| 自拍偷自拍亚洲精品第1页| 欧美成人片一区二区三区| 日本熟妇人妻xxxxx| 人人人爽人人爽人人av| 亚洲精品无码少妇30p| 东京热人妻丝袜av无码| 羞涩的丰满人妻40p| 人人妻人人澡av天堂香蕉| 午夜dv内射一区区| 少妇无码av无码专区线| 精品国产免费观看久久久| 久久天堂av综合合色| 成人aaa片一区国产精品| 狠狠色丁香婷婷久久综合| 中国少妇初尝黑人巨高清| 国产亚洲精品欧洲在线观看| 国产色xx群视频射精| 男人的好看免费观看在线视频 | 国产特级毛片aaaaaa |