在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Formyl-HIST1H1E (K62) Antibody

Formyl-HIST1H1E (K62) Antibody

  • 中文名稱：
    Formyl-HIST1H1E (K62)兔多克隆抗體
  • 貨號：
    CSB-PA010380OA62forHU
  • 規格：
    ￥440
  • 圖片：
    • Immunocytochemistry analysis of CSB-PA010380OA62forHU diluted at 1:10 and staining in Hela cells(treated with 30mM sodium butyrate for 4h) performed on a Leica BondTM system. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HIST1H1E
  • 別名：
    Histone H1.4 (Histone H1b) (Histone H1s-4), HIST1H1E, H1F4
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from Human Histone H1.4 protein (57-69aa)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    ICC 1:10-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻：
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關疾病：
    Rahman syndrome (RMNS)
  • 亞細胞定位：
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族：
    Histone H1/H5 family
  • 數據庫鏈接：

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板： 亚洲伊人丝袜精品久久| 亚洲精品一区久久久久一品av| 四虎精品成人免费视频| 97国产精品麻豆性色aⅴ人妻波 | 99精品国产丝袜在线拍国语| 亚洲欲色欲香天天综合网| 日本熟妇人妻xxxx| 成人精品视频一区二区三区 | 3d动漫精品一区二区三区 | 亚洲精品一区二区精华液| 无码播放一区二区三区| 亚洲一区精品无码| 香港经典a毛片免费观看hd| 天天摸天天做天天添欧美| 最新日韩精品中文字幕| 一色屋精品视频在线观看| 人妻系列无码专区av在线| 久久影院午夜伦手机不四虎卡| 久久99精品久久只有精品| 真人抽搐一进一出gif| 成年免费视频播放网站推荐| 亚洲精品中文字幕一区二区三区| 97久久超碰亚洲视觉盛宴| 抽插丰满内射高潮视频| 人妻无码中文专区久久五月婷| 久久亚洲精品中文字幕一区 | 国产成人精品无码专区| 亚洲日韩久热中文字幕| 曰韩a∨无码一区二区三区| 亚洲国产成人久久综合| 又黄又爽又猛的视频免费| 国产一区二区三区四区精华| 国产成人av 综合 亚洲| 精品国产18久久久久久| 久久亚洲人成综合网| 99国产揄拍国产精品人妻| 丝袜 中出 制服 人妻 美腿| www国产亚洲精品久久网站| 日日摸日日碰夜夜爽亚洲综合| 国产又粗又猛又爽又黄| 国产欧美久久一区二区三区|