在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Phospho-HIST1H1E (T145) Antibody

Phospho-HIST1H1E (T145) Antibody

  • 中文名稱：
    磷酸化-HIST1H1E (T145)兔多克隆抗體
  • 貨號：
    CSB-PA010380PA145phHU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunocytochemistry analysis of CSB-PA010380PA145phHU diluted at 1:10 and staining in Hela cells(treated with 50nM Calyculin A for 30min) performed on a Leica BondTM system. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HIST1H1E
  • 別名：
    Histone H1.4 (Histone H1b) (Histone H1s-4), HIST1H1E, H1F4
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from Human Histone H1.4 protein (140-151)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA, ICC
  • 推薦稀釋比：
    Application Recommended Dilution
    ICC 1:10-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻：
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關疾病：
    Rahman syndrome (RMNS)
  • 亞細胞定位：
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族：
    Histone H1/H5 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板： 成人毛片无码一区二区三区| 97在线观看播放| 国产成人精品一区二三区| 荡女精品导航| 欧美极p品少妇的xxxxx| 国产成人午夜在线视频a站| 国产成人精品一区二区三区| 国产精品久久久久av福利动漫| 无码写真精品永久福利在线| 亚洲一卡2卡3卡4卡5卡精品| 又大又粗又爽免费视频a片| 亚洲无线卡一卡二| 污污污污污污www网站免费| 综合三区后入内射国产馆| 国内永久福利在线视频图片| 国产午夜成人免费看片app| 国产精品成人av在线观看春天| 亚洲无线观看国产精品| 少妇无码av无码一区| 国偷自产视频一区二区久| 天天弄天天模| 久久久久久妓女精品影院| 亚洲色无码中文字幕手机在线| 亚洲日韩精品无码专区| 樱花影院电视剧免费| 又爽又黄又无遮挡网站| 国产全肉乱妇杂乱视频| 久久无码人妻丰满熟妇区毛片| 亚洲 综合 欧美在线视频| 久久99精品久久久久久蜜芽| 天美麻花果冻视频大全英文版| 欧美3p两根一起进高清免费视频| 成人免费视频在线观看地区免下载| 亚洲人成色77777在线观看大战p| 欧美激情性做爰免费视频| 国产精品一区二区av蜜芽| 久久成人伊人欧洲精品 | 久久婷婷五月综合97色直播| 999久久久精品国产消防器材| 樱桃视频影视在线观看免费| 国产99久久久久久免费看|