在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HIST1H1E (Ab-62) Antibody

HIST1H1E (Ab-62) Antibody

  • 中文名稱：
    HIST1H1E (Ab-62)兔多克隆抗體
  • 貨號：
    CSB-PA010380OA62nforHU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA010380OA62nforHU diluted at 1:20 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA010380OA62nforHU diluted at 1:20 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HIST1H1E Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HIST1H1E
  • 別名：
    Histone H1.4 (Histone H1b) (Histone H1s-4), HIST1H1E, H1F4
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from Human Histone H1.4 protein (57-69aa)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:10-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻：
    1. Results show that histones H1.2 and H1.4 were observed in MDA-MB-231 metastatic breast cancer cells. The phosphorylation at S173 of histone H1.2 and S172, S187, T18, T146, and T154 of H1.4 significantly increases during M phase suggesting that these events are cell cycle-dependent. PMID: 26209608
    2. This study identified and confirmed HIST1H1E protein changes within the postsynaptic density in schizophrenia. PMID: 25048004
    3. the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions. PMID: 22425985
    4. PKA-mediated H1.4S35 phosphorylation dissociates H1.4 from mitotic chromatin but also suggest that this phosphorylation is necessary for specific mitotic functions. PMID: 21852232
    5. Allele-specific underacetylation of histone H4 downstream from promoter is associated with X-inactivation in human cells. PMID: 12498347
    6. the lysine residue adjacent to the phosphorylation site found on the serine residue on the H1.4 peptide KARKSAGAAKR was also shown to be methylated, raising the question of whether the hypothesized "methyl/phos" switch could be extended to linker histones PMID: 15595731
    7. Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins PMID: 19144645

    顯示更多

    收起更多

  • 相關疾病：
    Rahman syndrome (RMNS)
  • 亞細胞定位：
    Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus.
  • 蛋白家族：
    Histone H1/H5 family
  • 數據庫鏈接：

    HGNC: 4718

    OMIM: 142220

    KEGG: hsa:3008

    STRING: 9606.ENSP00000307705

    UniGene: Hs.248133



主站蜘蛛池模板： 成人亚洲一区无码久久| 少妇高潮喷潮久久久影院| 999zyz玖玖资源站永久| 亚洲国产成人av人片久久| 欧美国产精品久久久乱码| 无码毛片一区二区本码视频| 国产精品人成视频免费999| 色欲av无码一区二区三区| 国产欧美另类精品久久久| 伊人久久精品亚洲午夜| 国产成人精品aa毛片| 亚洲成av人片一区二区密柚| 人人爽久久涩噜噜噜av| 狠狠躁夜夜躁人人爽天天bl| 人体内射精一区二区三区| 日本免费大黄在线观看| 丝袜老师办公室里做好紧好爽| 又大又粗又爽又黄的少妇毛片| 丰满白嫩人妻中出无码| 黑人玩弄出轨人妻松雪| 亚洲这里只有久热精品伊人| 女人被躁到高潮免费视频软件| 一个添下面两个吃奶把腿扒开| 最近中文字幕mv在线资源| 亚洲国产综合av在线观看| 国内少妇高潮嗷嗷叫在线播放 | 真人作爱免费视频| 色综合久久中文娱乐网| 久久久一本精品99久久精品66直播| 中文字幕无码精品亚洲资源网久久| 久久无码人妻精品一区二区三区 | 吃奶呻吟张开双腿做受在线播放| 伦埋琪琪电影院久久| 国产乱码免费卡1卡二卡3| 少妇高潮惨叫久久久久电影| 久久人人爽人人爽人人片av高清| 国产精品无码一区二区桃花视频| 777奇米四色成人影视色区| 天堂资源在线官网| 亚洲中文字幕无码永久在线| 特级做a爰片毛片免费看108 |