在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Lysophosphatidic acid receptor 4 (LPAR4)

  • 中文名稱:
    人LPAR4重組蛋白
  • 貨號:
    CSB-CF013050HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    LPAR4; GPR23; LPA4; P2RY9; Lysophosphatidic acid receptor 4; LPA receptor 4; LPA-4; G-protein coupled receptor 23; P2Y purinoceptor 9; P2Y9; P2Y5-like receptor; Purinergic receptor 9
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-370
  • 氨基酸序列
    MGDRRFIDFQFQDSNSSLRPRLGNATANNTCIVDDSFKYNLNGAVYSVVFILGLITNSVS LFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFNRHWPFGDTLCKISGTAFLT NIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLFSTTN VNNATTTCFEGFSKRVWKTYLSKITIFIEVVGFIIPLILNVSCSSVVLRTLRKPATLSQI GTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAITNCFLERFAKIMYPITLCLA TLNCCFDPFIYYFTLESFQKSFYINAHIRMESLFKTETPLTTKPSLPAIQEEVSDQTTNN GGELMLESTF
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1-alkyl- > 1-alkenyl-LPA.
  • 基因功能參考文獻:
    1. Mutation in LPAR4 gene is associated with papillary thyroid carcinoma. PMID: 26941397
    2. These results suggest that the diverse roles of LPA4, LPA5 and LPA6 are involved in the activation of tumor progression in pancreatic cancer cells. PMID: 25849892
    3. Our data suggest that LPA4 signaling potentially modulates malignant behavior of SQ-20B cells. PMID: 23467751
    4. LPA4 gene mutation may play some role in the pathogenesis of colon cancer. PMID: 20890765
    5. LPA4 and LPA5 receptors induce osteoblastic differentiation of human mesenchymal stem cells PMID: 20069565
    6. identified as the fourth lysophosphatidic acid (LPA) receptor; shares only 20-24% amino acid identities with Edg-2/LPA1, Edg-4/LPA2, and Edg-7/LPA3, and phylogenetic analysis also shows that p2y9/GPR23 is far distant from the Edg family PMID: 12724320

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    High expression in ovary. Not detected in the brain regions thalamus, putamen, caudate, frontal cortex, pons, hypothalamus and hippocampus.
  • 數據庫鏈接:

    HGNC: 4478

    OMIM: 300086

    KEGG: hsa:2846

    STRING: 9606.ENSP00000362398

    UniGene: Hs.522701



主站蜘蛛池模板: 久久精品人人槡人妻人人玩av| 少妇做爰免费视看片| 国产好大好硬好爽免费不卡| aaa欧美色吧激情视频| 国产午夜永久福利视频在线观看| 久久久久国产精品无码免费看| 国产精品久久久久影院| 久久大蕉香蕉免费| 国产日韩综合一区在线观看| 国产日韩一区二区三免费高清| 曰本丰满熟妇xxxx性| 一个人看免费视频www| 亚洲国产福利一区二区三区| 久久综合五月丁香六月丁香 | 骚虎成人免费99xx| 中文字幕av一区二区三区| 日韩精品极品视频在线观看免费| 久久亚洲精品情侣| 亚洲欧美成人中文日韩电影网站| 久久综合九色综合久99| 成人网站免费观看入口| 宅男午夜成年影视在线观看| 欧美肥老太交性506070| 日韩熟女精品一区二区三区| 人妻少妇精品视频无码综合| 无码人妻日韩一区日韩二区| 免费无码毛片一区二区三区a片| 色狠狠色噜噜av天堂一区| 精品国产一区二区三区av孞弋 | 女人被狂躁的高潮免费视频| 国产成人免费爽爽爽视频| 久久99亚洲含羞草影院| 欧美3p两根一起进高清视频| 天干天干天啪啪夜爽爽av| 在线播放国产不卡免费视频| 亚洲国产成人久久精品99| 国产真实夫妇视频| 国产极品粉嫩馒头一线天av| 久久人人97超碰国产精品| 四虎成人精品在永久免费| 久久香蕉超碰97国产精品|