在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Saccharomyces cerevisiae Securin (PDS1)

  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-YP019074SVG
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-EP019074SVG
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-EP019074SVG-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-BP019074SVG
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-MP019074SVG
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PDS1
  • Uniprot No.:
  • 別名:
    PDS1; YDR113C; YD9727.08C; Securin
  • 種屬:
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-373
  • 氨基酸序列
    MMPANEDKEN NIVYTGNESS GINFPQTPAH LLKRSHSNIL KPPVRLDQLK RDANSNNGNT LKYIQGGKEV SPTKRLHTHA QQQGRLPLAA KDNNRSKSFI FPETSNQSKD ADLPQLQNTL SIRKNDQLRK LSQISRSRSR ANHNDLLSNS RKLQKYGSVL GYNALPKMKS LVLKDLADSG KNEESSDDDE GNEDSESKLG KKLQSALLKQ DSSDGENELN GGLGLFNEQG GLQQLIKNST KNEQKTKNDK SDKTDDYDIE IAPQRQEPLP YVPEGYSPFQ QDDIEKLKTF NSPYKLDLED EDDTPDKVDL LPLEQIDEEG EKDETECITR NQEEGAALPL LSKNFKEVAA VPTMELVYSE EGLDPEELED LVT
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Regulatory protein, which plays a central role in chromosome stability. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESP1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESP1.
  • 基因功能參考文獻:
    1. crystal structures at up to 2.6 A resolution of the yeast Saccharomyces cerevisiae separase-securin complex PMID: 28146474
    2. These data indicate that Clb5 and Clb6 promote cohesion which is then protected by Pds1 and that both mechanisms are required during replication stress. PMID: 21518961
    3. Chk1-Pds1 checkpoint has roles in preventing tolerance of persistent single-strand breaks in Saccharomyces cerevisiae PMID: 15687272
    4. protein phosphatase 2A regulates sister chromatid cohesion in Pds1-dependent and -independent manners PMID: 17050679
    5. phosphorylation of Pds1 but not Rad53 correlates with G2 arrest in response to double-strand breaks in the mec1 hypomorphic mutant PMID: 17671432
    6. RAD9, CHK1 and PDS1 are required for elevated homologous recombination in a mec1 (ATR) hypomorphic mutant. PMID: 18677117
    7. These results define a previously undescribed role for Pds1p in cohesin maintenance, recombination, and meiotic progression. PMID: 19001291

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Securin family
  • 數據庫鏈接:

    KEGG: sce:YDR113C

    STRING: 4932.YDR113C



主站蜘蛛池模板: 蜜桃视频在线观看免费网址入口| 亚洲视频日本有码中文| 成人av在线一区二区三区| 国内少妇高潮嗷嗷叫在线播放| 色欲狠狠躁天天躁无码中文字幕| 老太婆性杂交视频| 麻豆精产一二三产区| 韩国 日本 亚洲 国产 不卡| 国产无人区码一码二码三mba| 亚洲欧美日韩国产成人精品影院| 国产亚洲精品久久久美女18黄| 国产欧美一区二区精品仙草咪| 波多野结av在线无码中文 | 少妇爱做高清免费视频| 免费无码一区二区三区蜜桃| 俺也来俺也去俺也射| 色8激情欧美成人久久综合电影| 亚洲日本精品国产一区vr| 国产精品久久久久久亚洲色| 国产情侣真实露脸在线| 成年美女黄的视频网站| av大片在线无码免费| 无码人妻aⅴ一区二区三区| 国产成人综合久久久久久| 国产精品欧美成人片| 久久99国产精品久久99| 色一情一区二区三区四区| 色欲久久人妻内射| 亚洲男男无套gv大学生| 国产亚州精品女人久久久久久| 天堂国产一区二区三区| 国产成人美女裸体片免费看| 亚洲国产精品久久久久久久| 国产精品自在在线午夜| 国产精品亚洲综合久久系列| 免费无码专区在线视频| 人妻少妇精品视频二区| 国产精品无码专区久久久| 蜜臀av片在线观看| 亚洲综合图色40p| 免费一本色道久久一区|