在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Saccharomyces cerevisiae Securin (PDS1)

  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-YP019074SVG
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-EP019074SVG
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-EP019074SVG-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-BP019074SVG
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-MP019074SVG
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PDS1
  • Uniprot No.:
  • 別名:
    PDS1; YDR113C; YD9727.08C; Securin
  • 種屬:
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-373
  • 氨基酸序列
    MMPANEDKEN NIVYTGNESS GINFPQTPAH LLKRSHSNIL KPPVRLDQLK RDANSNNGNT LKYIQGGKEV SPTKRLHTHA QQQGRLPLAA KDNNRSKSFI FPETSNQSKD ADLPQLQNTL SIRKNDQLRK LSQISRSRSR ANHNDLLSNS RKLQKYGSVL GYNALPKMKS LVLKDLADSG KNEESSDDDE GNEDSESKLG KKLQSALLKQ DSSDGENELN GGLGLFNEQG GLQQLIKNST KNEQKTKNDK SDKTDDYDIE IAPQRQEPLP YVPEGYSPFQ QDDIEKLKTF NSPYKLDLED EDDTPDKVDL LPLEQIDEEG EKDETECITR NQEEGAALPL LSKNFKEVAA VPTMELVYSE EGLDPEELED LVT
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Regulatory protein, which plays a central role in chromosome stability. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESP1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESP1.
  • 基因功能參考文獻:
    1. crystal structures at up to 2.6 A resolution of the yeast Saccharomyces cerevisiae separase-securin complex PMID: 28146474
    2. These data indicate that Clb5 and Clb6 promote cohesion which is then protected by Pds1 and that both mechanisms are required during replication stress. PMID: 21518961
    3. Chk1-Pds1 checkpoint has roles in preventing tolerance of persistent single-strand breaks in Saccharomyces cerevisiae PMID: 15687272
    4. protein phosphatase 2A regulates sister chromatid cohesion in Pds1-dependent and -independent manners PMID: 17050679
    5. phosphorylation of Pds1 but not Rad53 correlates with G2 arrest in response to double-strand breaks in the mec1 hypomorphic mutant PMID: 17671432
    6. RAD9, CHK1 and PDS1 are required for elevated homologous recombination in a mec1 (ATR) hypomorphic mutant. PMID: 18677117
    7. These results define a previously undescribed role for Pds1p in cohesin maintenance, recombination, and meiotic progression. PMID: 19001291

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Securin family
  • 數據庫鏈接:

    KEGG: sce:YDR113C

    STRING: 4932.YDR113C



主站蜘蛛池模板: 欧美三级欧美成人高清| 欧美激情一区二区成人| 中文字幕日韩精品亚洲一区 | 亚洲精品蜜夜内射| 国产午夜精品一区二区三区嫩草| 国产jjzzjjzz视频全部免费| 亚洲日韩小电影在线观看| 亚洲麻豆av成本人无码网站| 亚洲精品揄拍自拍首页一| 人妻互换一二三区激情视频| 十八18禁国产精品www| 免费国产a国产片高清| 国产乱人伦av在线a更新| 欧美做受视频播放| 强奷妇系列中文字幕| 国产精品无码一区二区三区免费| 亚洲色婷婷久久精品av蜜桃久久| 日韩一区二区在线观看视频| 国产免费人成视频尤勿视频| 男女啪啪抽搐呻吟高潮动态图| 夜夜夜夜猛噜噜噜噜噜| 人妻无码第一区二区三区| 色悠久久久久久久综合网伊人| 亚洲国产成人极品综合| 蜜芽av无码精品国产午夜| 男人狂躁进女人下面免费视频| 国产真人性做爰久久网站| 久久久久久久久久久国产| 久久久久青草线综合超碰| 奇米777四色成人影视| 亚洲综合色视频在线观看| 亚洲夜夜性无码| 国内揄拍国产精品人妻门事件| 无码国产激情在线观看| 高中国产开嫩苞实拍视频在线观看| 在线精品国产一区二区三区| 天天躁日日躁狠狠躁欧美老妇小说 | 天天拍夜夜添久久精品| 一本色道久久88精品综合| 后入到高潮免费观看| 大肉大捧一进一出视频|