在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Saccharomyces cerevisiae Securin (PDS1)

  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-YP019074SVG
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-EP019074SVG
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-EP019074SVG-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-BP019074SVG
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    釀酒酵母PDS1重組蛋白
  • 貨號:
    CSB-MP019074SVG
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PDS1
  • Uniprot No.:
  • 別名:
    PDS1; YDR113C; YD9727.08C; Securin
  • 種屬:
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-373
  • 氨基酸序列
    MMPANEDKEN NIVYTGNESS GINFPQTPAH LLKRSHSNIL KPPVRLDQLK RDANSNNGNT LKYIQGGKEV SPTKRLHTHA QQQGRLPLAA KDNNRSKSFI FPETSNQSKD ADLPQLQNTL SIRKNDQLRK LSQISRSRSR ANHNDLLSNS RKLQKYGSVL GYNALPKMKS LVLKDLADSG KNEESSDDDE GNEDSESKLG KKLQSALLKQ DSSDGENELN GGLGLFNEQG GLQQLIKNST KNEQKTKNDK SDKTDDYDIE IAPQRQEPLP YVPEGYSPFQ QDDIEKLKTF NSPYKLDLED EDDTPDKVDL LPLEQIDEEG EKDETECITR NQEEGAALPL LSKNFKEVAA VPTMELVYSE EGLDPEELED LVT
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Regulatory protein, which plays a central role in chromosome stability. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESP1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESP1.
  • 基因功能參考文獻:
    1. crystal structures at up to 2.6 A resolution of the yeast Saccharomyces cerevisiae separase-securin complex PMID: 28146474
    2. These data indicate that Clb5 and Clb6 promote cohesion which is then protected by Pds1 and that both mechanisms are required during replication stress. PMID: 21518961
    3. Chk1-Pds1 checkpoint has roles in preventing tolerance of persistent single-strand breaks in Saccharomyces cerevisiae PMID: 15687272
    4. protein phosphatase 2A regulates sister chromatid cohesion in Pds1-dependent and -independent manners PMID: 17050679
    5. phosphorylation of Pds1 but not Rad53 correlates with G2 arrest in response to double-strand breaks in the mec1 hypomorphic mutant PMID: 17671432
    6. RAD9, CHK1 and PDS1 are required for elevated homologous recombination in a mec1 (ATR) hypomorphic mutant. PMID: 18677117
    7. These results define a previously undescribed role for Pds1p in cohesin maintenance, recombination, and meiotic progression. PMID: 19001291

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Securin family
  • 數據庫鏈接:

    KEGG: sce:YDR113C

    STRING: 4932.YDR113C



主站蜘蛛池模板: 国产香蕉尹人在线视频你懂的| 欧美老人巨大xxxx做受| 国自产拍偷拍精品啪啪一区二区| 国产精品18禁污污网站| 中国极品少妇xxxxx| 成人精品视频一区二区三区尤物 | 国产高清在线精品一区二区三区| 国产普通话对白刺激| 国产乱妇无乱码大黄aa片| 国产嘿嘿嘿视频在线观看| 国内精品视频一区二区八戒| 欧美老妇人与禽交| 日本丰满白嫩大屁股ass| 日韩欧美亚洲综合久久影院d3| 亚洲国产av导航第一福利网 | 国产熟睡乱子伦视频| 国产成人啪精品视频免费网站软件 | 精品福利视频一区二区三区| 国产真实自在自线免费精品| 亚洲国产区男人本色vr| 上司的丰满人妻中文字幕| 亚洲小说区图片区另类春色| 日韩av爽爽爽久久久久久| 国产高清国产精品国产专区| 无码成人一区二区三区| 小雪好紧好滑好湿好爽视频| 国内丰满熟女出轨videos| 三上悠亚久久精品| 国产精品无码mv在线观看| 久久亚洲色www成人男男| 人妻av无码专区| 99久久婷婷国产综合精品电影 | 精品无码中文视频在线观看 | av永久天堂一区二区三区| 天堂av男人在线播放| 国产免费啪嗒啪嗒视频看看| 蜜桃av蜜臀av色欲av麻| 国产午夜片无码区在线播放| 一本久久综合亚洲鲁鲁五月天| 日韩精品专区在线影院重磅| 欧美日韩综合一区二区三区 |