在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PDS1 Antibody

PDS1 Antibody

Rare Species
  • 中文名稱：
    PDS1 Antibody
  • 貨號：
    CSB-PA019074XA01SVG
  • 規格：
    ￥880
  • 圖片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: PDS1 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 35 kDa
      Observed band size: 35 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PDS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PDS1
  • 別名：
    Securin PDS1 YDR113C YD9727.08C
  • 宿主：
    Rabbit
  • 反應種屬：
    Saccharomyces cerevisiae (Baker's yeast)
  • 免疫原：
    Recombinant Saccharomyces cerevisiae (Baker's yeast) PDS1 protein (240-369aa)
  • 免疫原種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulatory protein, which plays a central role in chromosome stability. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESP1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESP1.
  • 基因功能參考文獻：
    1. crystal structures at up to 2.6 A resolution of the yeast Saccharomyces cerevisiae separase-securin complex PMID: 28146474
    2. These data indicate that Clb5 and Clb6 promote cohesion which is then protected by Pds1 and that both mechanisms are required during replication stress. PMID: 21518961
    3. Chk1-Pds1 checkpoint has roles in preventing tolerance of persistent single-strand breaks in Saccharomyces cerevisiae PMID: 15687272
    4. protein phosphatase 2A regulates sister chromatid cohesion in Pds1-dependent and -independent manners PMID: 17050679
    5. phosphorylation of Pds1 but not Rad53 correlates with G2 arrest in response to double-strand breaks in the mec1 hypomorphic mutant PMID: 17671432
    6. RAD9, CHK1 and PDS1 are required for elevated homologous recombination in a mec1 (ATR) hypomorphic mutant. PMID: 18677117
    7. These results define a previously undescribed role for Pds1p in cohesin maintenance, recombination, and meiotic progression. PMID: 19001291

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Securin family
  • 數據庫鏈接：

    KEGG: sce:YDR113C

    STRING: 4932.YDR113C



主站蜘蛛池模板： 女人被黑人狂躁c到高潮小说| 久热这里只有精品12| 久碰人妻人妻人妻人妻人掠| 欧美最猛黑人xxxx| 在线欧美日韩制服国产| 国产福利萌白酱精品一区| 亚洲中文字幕第一页在线| 精品久久久久久中文字幕大豆网| 成人性生交大片免费看视频app| 男女啪啪做爰高潮无遮挡| 女高中生第一次破苞av| 久久日本片精品aaaaa国产| 最近更新中文字幕| 亚洲a片国产av一区无码| 无码午夜福利视频1000集| 中文字幕人成人乱码亚洲电影 | 亚洲午夜福利精品无码不卡| 麻豆精品久久久久久久99蜜桃| 性生交大片免费看l| 国产99视频精品免费视频76| 综合亚洲桃色第一影院| 日韩成人无码一区二区三区| 成人午夜看黄在线尤物成人 | 内射极品少妇xxxxxhd| 羞羞视频在线观看| 国产xxx视频在线观看软件| 精品国产一区二区三区免费| 强奷乱码中文字幕熟女导航| 亚洲国产综合av在线观看| 人妻系列无码专区无码中出| 四虎影库在线永久影院免费观看| 老妇高潮潮喷到猛进猛出| 777yyy亚洲精品久久久| 欧美综合天天夜夜久久| 一区二区三区国产亚洲网站| 无码精品国产一区二区免费| 亚洲精品揄拍自拍首页一 | 农村老熟妇乱子伦视频| 毛片24种姿势无遮无拦| 亚洲婷婷开心色四房播播| 欧美午夜成人片在线观看|