在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rabbit Apolipoprotein E (APOE), partial

In Stock
  • 中文名稱:
    Recombinant Rabbit Apolipoprotein E(APOE),partial
  • 貨號:
    CSB-EP001936RBb3
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    APOEApolipoprotein E; Apo-E
  • 種屬:
    Oryctolagus cuniculus (Rabbit)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    53.6kDa
  • 表達區域:
    20-311aa
  • 氨基酸序列
    TEQEVEVPEQARWKAGQPWELALGRFWDYLRWVQSLSDQVQEELLSSQVTQELTMLMEETMKEVKAYKSELEEQLSPMAQEHRARLSKELQVAGALEADMEDVCNRLAQYRGEAQAMLGQSTEELARAFSSHLRKLRKRLLRDAEDLQKRMAVYGAGAREGAERGVSAVRERLGSRLERGRLRVATVGTLAGRPLRERAQAWGERLRGHLEEVGSRARDRLNEVREQVEEVRVKVEEQAPQMRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKLQAAMPSKAPAAAPIENQ
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles. Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
  • 基因功能參考文獻:
    1. we report the efficient creation of an APOE knockout rabbit by using zinc finger nucleases. The knockout rabbits had drastically elevated cholesterol and moderately increased triglyceride levels, mimicking symptoms in human heart disease. PMID: 25216764
    2. These differentially expressed proteins associated with key mechanisms involved in atherosclerosis and signaling mechanisms related with vitamin E. PMID: 23796494
    3. The molar ratio ApoE/ApoA-I is negatively correlated with the enzyme activity, and positively correlated with increases in the intima-media thickness of common carotid wall and cardiac dysfunction signs. PMID: 22562159
    4. ApoE mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL paraoxonase activity PMID: 20221865
    5. The identification of disulphide-linked apoE dimers in cortical and hippocampal tissues represents a distinct structural difference between the apoE3 and apoE4 isoforms that may have functional consequences. PMID: 20170526

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Apolipoprotein A1/A4/E family
  • 數據庫鏈接:

    KEGG: ocu:100009337

    UniGene: Ocu.6224



主站蜘蛛池模板: 2022国产日产欧产精品| 怡春院久久国语视频免费| 未满十八18禁止免费无码网站| 成年奭片免费观看视频天天看| 99这里有精品视频视频| 国产乱码二卡3卡四卡| 久久久久成人网站| 337人体做爰大胆视频| 骚女人干起来舒服视频在线| 伊人久久大香线蕉综合狠狠| 内射老阿姨1区2区3区4区| 无码人妻一区二区三区免费看 | 亚洲成av人片在www鸭子| 久久久久人妻一区二区三区| 久久久www成人免费无遮挡大片| 精品人妻少妇嫩草av无码专区| 免费人成网视频在线观看| 手机真实国产乱子伦对白视频| 亚洲欭美日韩颜射在线二| 欧洲熟妇色xxxxx欧美老妇伦| 丰满护士巨好爽好大乳| 高潮射精日本韩国在线播放| 极品美女扒开粉嫩小泬| 玩弄japan白嫩少妇hd| 国产精品人妻久久毛片高清无卡| 国产精品人成电影在线观看| 自拍偷自拍亚洲精品情侣| 亚洲午夜无码久久久久| 国产成人精品视频网站| 国产jk白丝在线观看免费| 亚洲天堂男人影院| 加比勒色综合久久| 又色又爽又黄的美女裸体网站| 三上悠亚ssⅰn939无码播放| 免费看成人欧美片爱潮app| 亚洲午夜成人精品无码app| av无码免费岛国动作片不卡| 久久久久久自慰出白浆| 久久精品99av高久久精品| 欧美伊人色综合久久天天| 伦埋琪琪电影院久久|