在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rabbit Apolipoprotein E (APOE)

  • 中文名稱:
    Recombinant Rabbit Apolipoprotein E(APOE)
  • 貨號:
    CSB-YP001936RB
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Rabbit Apolipoprotein E(APOE)
  • 貨號:
    CSB-EP001936RB-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Rabbit Apolipoprotein E(APOE)
  • 貨號:
    CSB-BP001936RB
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Rabbit Apolipoprotein E(APOE)
  • 貨號:
    CSB-MP001936RB
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    APOEApolipoprotein E; Apo-E
  • 種屬:
    Oryctolagus cuniculus (Rabbit)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    19-311
  • 氨基酸序列
    QT EQEVEVPEQA RWKAGQPWEL ALGRFWDYLR WVQSLSDQVQ EELLSSQVTQ ELTMLMEETM KEVKAYKSEL EEQLSPMAQE HRARLSKELQ VAGALEADME DVCNRLAQYR GEAQAMLGQS TEELARAFSS HLRKLRKRLL RDAEDLQKRM AVYGAGAREG AERGVSAVRE RLGSRLERGR LRVATVGTLA GRPLRERAQA WGERLRGHLE EVGSRARDRL NEVREQVEEV RVKVEEQAPQ MRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKLQAAMPS KAPAAAPIEN Q
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles. Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
  • 基因功能參考文獻:
    1. we report the efficient creation of an APOE knockout rabbit by using zinc finger nucleases. The knockout rabbits had drastically elevated cholesterol and moderately increased triglyceride levels, mimicking symptoms in human heart disease. PMID: 25216764
    2. These differentially expressed proteins associated with key mechanisms involved in atherosclerosis and signaling mechanisms related with vitamin E. PMID: 23796494
    3. The molar ratio ApoE/ApoA-I is negatively correlated with the enzyme activity, and positively correlated with increases in the intima-media thickness of common carotid wall and cardiac dysfunction signs. PMID: 22562159
    4. ApoE mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL paraoxonase activity PMID: 20221865
    5. The identification of disulphide-linked apoE dimers in cortical and hippocampal tissues represents a distinct structural difference between the apoE3 and apoE4 isoforms that may have functional consequences. PMID: 20170526

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Apolipoprotein A1/A4/E family
  • 數據庫鏈接:

    KEGG: ocu:100009337

    UniGene: Ocu.6224



主站蜘蛛池模板: 欧美巨大另类极品videosbest| 97在线观看播放| 欧美人妻精品一区二区三区| 亚洲成av人片在线观看无码不卡| 2020国产欧洲精品网站| 久久亚洲精品无码av宋| 中文字幕精品一二三四五六七八 | 99久久精品无码一区二区三区| 亚洲欧洲日产国码久在线| 扒开双腿猛进入喷水高潮叫声| 最新国产麻豆aⅴ精品无码 | 精品乱码无人区一区二区| 高清国产在线拍揄自揄视频| 久久偷看各类wc女厕嘘嘘偷窃 | 99久久99久久精品国产片果冻| 亚洲ⅴ国产v天堂a无码二区| 老司机久久一区二区三区| 色综合伊人色综合网站无码| 亚洲色婷婷一区二区三区| 精品国际久久久久999| 狠狠躁夜夜躁人人爽天天bl| 中国免费看的片| 性生交大全免费看| 久久久久久久岛国免费观看 | 欧美香蕉爽爽人人爽| 国产精品人妻一区二区高| 亚洲最大天堂无码精品区| 国产成人一区二区三区在线观看| 天堂va欧美ⅴa亚洲va| 毛片免费视频| 老司机午夜免费精品视频| 天天摸天天做天天爽天天弄| 色悠久久久久综合先锋影音下载| 丰满亚洲大尺度无码无码专线| 97精品一区二区视频在线观看| 在线毛片片免费观看| 性暴力欧美猛交在线播放| 国产成人综合久久亚洲精品 | 丰满少妇弄高潮了www| 无线日本视频精品| 四虎精品成人a在线观看|