在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Pongo abelii Lys-63-specific deubiquitinase BRCC36 (BRCC3)

Recombinant Pongo abelii Lys-63-specific deubiquitinase BRCC36 (BRCC3)

  • 中文名稱：
    Recombinant Pongo abelii Lys-63-specific deubiquitinase BRCC36(BRCC3)
  • 貨號：
    CSB-YP735747PYX
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Pongo abelii Lys-63-specific deubiquitinase BRCC36(BRCC3)
  • 貨號：
    CSB-EP735747PYX
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Pongo abelii Lys-63-specific deubiquitinase BRCC36(BRCC3)
  • 貨號：
    CSB-EP735747PYX-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Pongo abelii Lys-63-specific deubiquitinase BRCC36(BRCC3)
  • 貨號：
    CSB-BP735747PYX
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Pongo abelii Lys-63-specific deubiquitinase BRCC36(BRCC3)
  • 貨號：
    CSB-MP735747PYX
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    BRCC3; BRCC36; Lys-63-specific deubiquitinase BRCC36; EC 3.4.19.-; BRCA1-A complex subunit BRCC36; BRCA1/BRCA2-containing complex subunit 3; BRCA1/BRCA2-containing complex subunit 36; BRISC complex subunit BRCC36
  • 種屬：
    Pongo abelii (Sumatran orangutan)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-247
  • 氨基酸序列
    AVQVVQAVQ AVHLESDAFL VCLNHALSTE KEEVMGLCIG ELNDDTRSDS KFAYTGTEMR TVAEKVDAVR IVHIHSVIIL RRSDKRKDRV EISPEQLSAA STEAERLAEL TGRPMRVVGW YHSHPHITVW PSHVDVRTQA MYQMMDQGFV GLIFSCFIED KNTKTGRVLY TCFQSIQAQK SSDLTHLDSV TKIHNGSVFT KNLCSQMSAV SGPLLQWLED RLEQNQQHLQ ELQQEKEELM QELSSLE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, antagonizing the RNF8-dependent ubiquitination at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1. Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activity by enhancing its stability and cell surface expression. Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination.
  • 亞細胞定位：
    Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole.
  • 蛋白家族：
    Peptidase M67A family, BRCC36 subfamily
  • 數據庫鏈接：

    KEGG: pon:100172840

    UniGene: Pab.3487



主站蜘蛛池模板： 国产午夜精华2020在线| 欧美性生交大片18禁止| 国产人妻aⅴ色偷| 天堂va欧美va亚洲va好看va| 久久只精品99品免费久23| 国产免费无码一区二区三区| 2020久久香蕉国产线看观看| 国产99视频精品免费视频36| 国产好大好硬好爽免费视频| 欧美成人片在线观看| 中文字幕无码日韩专区免费| 亚洲视频无码高清在线| 人妻精品人妻无码一区二区三区| 麻花传媒在线mv免费观看视频 | 720lu国产刺激无码| 131美女爱做视频免费| 无码人妻丰满熟妇啪啪| 国产在线精品无码二区| 久久久国产99久久国产久一| 屁屁影院ccyy备用地址| 99精品国产兔费观看久久99| 亚洲高潮喷水无码av电影| 综合亚洲综合图区网友自拍| 日本精品少妇一区二区三区| 中文人妻av久久人妻水密桃| 亚洲伊人色欲综合网无码中文| 欧美日韩综合一区二区三区| 国产日产欧产美| 韩国19禁主播深夜福利视频| 被灌满精子的波多野结衣| 国产舌乚八伦偷品w中| 国产精品亚洲精品一区二区| 爽到高潮无码视频在线观看| 国产黄大片在线观看画质优化| 18禁黄网站禁片免费观看国产| 人妻少妇无码专视频在线| 丰满的少妇xxxxx青青青| 四虎影视国产精品久久| 日韩欧美偷拍高跟鞋精品一区| 中文乱码免费一区二区三区| 国产人妻黑人一区二区三区|