在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human IGF-like family receptor 1 (IGFLR1), partial (Active)

In Stock
  • 中文名稱(chēng):
    人IGFLR1重組蛋白
  • 貨號(hào):
    CSB-MP862025HU
  • 規(guī)格:
    ¥828
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Activity
      Measured by its binding ability in a functional ELISA. Immobilized Human IGFLR1 at 2 μg/ml can bind Human IGFL1 (CSB-MP764932HU), the EC50 is 32.33-47.52 ng/mL.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
  • 內(nèi)毒素:
    Less than 1.0 EU/ug as determined by LAL method.
  • 生物活性:
    Measured by its binding ability in a functional ELISA. Immobilized Human IGFLR1 at 2 μg/mL can bind Human IGFL1 (CSB-MP764932HU), the EC50 is 32.33-47.52 ng/mL.
  • 基因名:
  • Uniprot No.:
  • 別名:
    (Transmembrane protein 149)(U2 small nuclear RNA auxiliary factor 1-like 4)
  • 分子結(jié)構(gòu):
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Partial
  • 來(lái)源:
    Mammalian cell
  • 分子量:
    17.4 kDa
  • 表達(dá)區(qū)域:
    23-163aa
  • 氨基酸序列
    SQYCGRLEYWNPDNKCCSSCLQRFGPPPCPDYEFRENCGLNDHGDFVTPPFRKCSSGQCNPDGAELCSPCGGGAVTPTPAAGGGRTPWRCRERPVPAKGHCPLTPGNPGAPSSQERSSPASSIAWRTPEPVPQQAWPNFLP
  • 蛋白標(biāo)簽:
    C-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產(chǎn)品描述:

    This Human?IGFLR1?(TMEM149, U2AF1L4)?recombinant protein was produced in Mammalian cell, where the gene sequence encoding Human IGFLR1 (23-163aa) was expressed with the C-terminal 6xHis?tag. The purity of this IGFLR1 protein was greater than 95% by SDS-PAGE. The activity was measured by its binding ability in a functional ELISA.

    IGFLR1 may also be involved in the immune system as a member of the TNF receptor family. Studies have found that in colorectal cancer, IGFLR1 is highly expressed on the surface of CD8+ T cells and has the function of depleting T cells. Inhibiting the expression of IGFLR1 may slow the progression of colorectal cancer tumors. In colorectal cancer patients, CXCL13+TH1-like cells may affect the therapeutic effect of immune checkpoint inhibitors. IGFLR1 is a type of receptor protein that is highly expressed on CXCL13+TH1-like cells. In vitro experiments in vivo demonstrated that IGFLR1, as a co-stimulatory factor, may become a potential drug therapy target.

  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Probable cell membrane receptor for the IGF-like family proteins. Binds IGFL1 and IGFL3 with a higher affinity. May also bind IGFL2.
  • 基因功能參考文獻(xiàn):
    1. Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member, IGFLR1. PMID: 21454693
  • 亞細(xì)胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 23620

    OMIM: 614143

    KEGG: hsa:79713

    STRING: 9606.ENSP00000246532

    UniGene: Hs.352548



主站蜘蛛池模板: 久久精品国产久精国产果冻传媒| av怡红院一区二区三区| 亚洲男人av香蕉爽爽爽爽| 亚无码乱人伦一区二区| 狼友av永久网站免费观看孕交| 欧美老妇乱辈通奷| 四虎国产精品永久在线观看| 2021无码最新国产在线观看| 人妻少妇久久中文字幕456| 欧美婷婷六月丁香综合| 最新精品国偷自产在线美女足| 国产激情久久久久久熟女老人 | 青草草97久热精品视频| 欧美亚洲精品一区二区 | 亚洲国产成人久久一区二区三区| 欧美日韩精品无码一本二本三本色 | 极品尤物被啪到呻吟喷水| 亚洲韩国日本高清一区| 亚洲国产成人精品无码区一本 | 中文字幕无码人妻aaa片| 中文字幕乱码人在线视频1区| 琪琪午夜理论片福利在线观看 | 伊人久久精品亚洲午夜| 精品少妇无码av无码专区| 国产精品久久久久久久妇| 日本伦奷在线播放| 精品久久久久久久无码| 免费无码va一区二区三区| 三级成年网站在线观看级爱网| 人妻三级日本香港三级极97| 亚洲综合无码一区二区| 亚洲成在人线免费观看| 两性色午夜视频免费老司机| 激情航班h版在线观看| 熟妇的味道hd中文字幕| 亚洲日韩av片在线观看| 精品露脸国产偷人在视频| 国产精品久久久久久久久免费 | 摸丰满大乳奶水www免费| 18禁真人抽搐一进一出在线| 日本免费高清一本视频|