在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Zona pellucida sperm-binding protein 3 (ZP3), partial

In Stock
  • 中文名稱:
    人ZP3重組蛋白
  • 貨號:
    CSB-MP027121HU
  • 規格:
    ¥2640
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    ZP3
  • Uniprot No.:
  • 別名:
    HUMZP3; Processed zona pellucida sperm-binding protein 3; Sperm receptor; zona pellucida glycoprotein 3 (sperm receptor); Zona pellucida glycoprotein 3; zona pellucida glycoprotein 3A (sperm receptor); Zona pellucida glycoprotein ZP3; Zona pellucida protein C; Zona pellucida sperm binding protein 3 precursor; Zp-3; ZP3 372; ZP3 424; ZP3 474; ZP3; ZP3_HUMAN; ZP3A; ZP3A/ZP3B; ZP3B; ZPC
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    partial
  • 來源:
    Mammalian cell
  • 分子量:
    44.6kDa
  • 表達區域:
    23-387aa
  • 氨基酸序列
    QPLWLLQGGASHPETSVQPVLVECQEATLMVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECGNSMQVTDDALVYSTFLLHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCGTPSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWALPSDTSV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
  • 基因功能參考文獻:
    1. The zona pellucida-3 (ZP3) protein plays a pivotal role in oocyte and gamete development. PMID: 30341457
    2. The oocyte ZP3 expression was the main predictor of the fertilization capacity. PMID: 28204536
    3. Missense Mutation in ZP3 gene is associated with Empty Follicle Syndrome and Female Infertility. PMID: 28886344
    4. Epididymal CRISP1 mediates sperm-zona pellucida binding through its interaction with ZP3. PMID: 24334245
    5. observed sequence variations in exons of ZP3 gene in women with infertility of unknown origin who exhibit abnormal zona pellucida; sperm-ovum interactions appear relatively normal in these patients [CASE REPORTS] PMID: 22889493
    6. Eggs expressing glycoprotein huZP3, derived from transgenic mice, bind murine but not human sperm, implying that huZP3 acquires the same O-glycans as native mZP3. PMID: 14673092
    7. human and mouse ZP3 proteins are quite similar, and alternative explanations of taxon-specific sperm binding warrant exploration PMID: 15379548
    8. Binding sites for recombinant zona pellucida C (ZPC) glycoprotein are located both at the N- and C-terminus of proacrosin PMID: 15950651
    9. Peptides rhuZP3a22 approximately 176 and rhuZP3b177 approximately 348 have a role similar to human ZP3. The mechanism of the response to the peptides involves influx of calcium, the G protein pathway, and a T-type calcium channel. PMID: 17192598
    10. may have a role in the development of primordial follicle before zona pellucida formation PMID: 18502569
    11. induces acrosome reactions which are protein kinase-C, protein tyrosine kinase, T-type Ca2+ channels, and extracellular Ca2+ dependent PMID: 18667750
    12. a significant decrease in acrosomal exocytosis mediated by both recombinant human ZP3 (p<0.005) and ZP4 (p<0.005) was observed in presence of the immune sera PMID: 19004505
    13. The functional activity of human ZP3 resides in its C-terminal domain. PMID: 19246320

    顯示更多

    收起更多

  • 相關疾病:
    Oocyte maturation defect 3 (OOMD3)
  • 亞細胞定位:
    [Processed zona pellucida sperm-binding protein 3]: Zona pellucida.; Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    ZP domain family, ZPC subfamily
  • 組織特異性:
    Expressed in oocytes (at protein level).
  • 數據庫鏈接:

    HGNC: 13189

    OMIM: 182889

    KEGG: hsa:7784

    STRING: 9606.ENSP00000378326

    UniGene: Hs.656137



主站蜘蛛池模板: 中文字幕有码无码人妻av蜜桃| 中国少妇内射xxxhd| 国产精品极品在线拍| 久久久久亚洲精品中文字幕| 美女高潮黄又色高清视频免费| 风韵人妻丰满熟妇老熟女| 国产精品白丝av网站| 国产热re99久久6国产精品首页 | 538在线精品视频| 国产精品无码成人午夜电影| 亚洲欧美日韩综合一区| 激情综合激情五月俺也去| 国产乱子伦一区二区三区视频播放 | 亚洲国产精品自在拍在线播放蜜臀| 国产亚洲人成网站在线观看| 免费无码一区二区三区a片百度| 鲁一鲁一鲁一鲁一澡| 欧美成人a天堂片在线观看| 国产人妻精品一区二区三首| 欧美拍拍视频免费大全| 国产在线拍偷自揄拍无码 | 日韩国产丝袜人妻一二区| 午夜福利啪啪无遮挡免费| 熟妇的奶头又大又长奶水视频| 亚洲国产中文在线二区三区免 | 人妻无码中文字幕| 日本高清在线www3344| 久久国产精品成人片免费| 久久精品黄aa片一区二区三区| 欧美成va视频网站| 成人做受120秒试看试看视频| 亚洲性久久久影院| 国产成人麻豆精品午夜福利在线| 人人玩人人添人人澡欧美| 无码国内精品久久人妻| 久久国产劲爆∧v内射-百度| 美女裸奶100%无遮挡免费网站| 无码毛片一区二区本码视频| 国产乱人伦app精品久久| 亚洲中文字幕永久在线不卡| 一边啪啪一边呻吟av夜夜嗨|