在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Zona pellucida sperm-binding protein 3 (ZP3), partial

  • 中文名稱:
    人ZP3重組蛋白
  • 貨號:
    CSB-YP027121HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人ZP3重組蛋白
  • 貨號:
    CSB-EP027121HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人ZP3重組蛋白
  • 貨號:
    CSB-BP027121HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    ZP3
  • Uniprot No.:
  • 別名:
    HUMZP3; Processed zona pellucida sperm-binding protein 3; Sperm receptor; zona pellucida glycoprotein 3 (sperm receptor); Zona pellucida glycoprotein 3; zona pellucida glycoprotein 3A (sperm receptor); Zona pellucida glycoprotein ZP3; Zona pellucida protein C; Zona pellucida sperm binding protein 3 precursor; Zp-3; ZP3 372; ZP3 424; ZP3 474; ZP3; ZP3_HUMAN; ZP3A; ZP3A/ZP3B; ZP3B; ZPC
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 分子量:
    38.0kDa
  • 表達區域:
    23-346aa
  • 氨基酸序列
    QPLWLLQGGASHPETSVQPVLVECQEATLMVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECGNSMQVTDDALVYSTFLLHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCGTPSHSRRQPHVMSQWSRS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
  • 基因功能參考文獻:
    1. The zona pellucida-3 (ZP3) protein plays a pivotal role in oocyte and gamete development. PMID: 30341457
    2. The oocyte ZP3 expression was the main predictor of the fertilization capacity. PMID: 28204536
    3. Missense Mutation in ZP3 gene is associated with Empty Follicle Syndrome and Female Infertility. PMID: 28886344
    4. Epididymal CRISP1 mediates sperm-zona pellucida binding through its interaction with ZP3. PMID: 24334245
    5. observed sequence variations in exons of ZP3 gene in women with infertility of unknown origin who exhibit abnormal zona pellucida; sperm-ovum interactions appear relatively normal in these patients [CASE REPORTS] PMID: 22889493
    6. Eggs expressing glycoprotein huZP3, derived from transgenic mice, bind murine but not human sperm, implying that huZP3 acquires the same O-glycans as native mZP3. PMID: 14673092
    7. human and mouse ZP3 proteins are quite similar, and alternative explanations of taxon-specific sperm binding warrant exploration PMID: 15379548
    8. Binding sites for recombinant zona pellucida C (ZPC) glycoprotein are located both at the N- and C-terminus of proacrosin PMID: 15950651
    9. Peptides rhuZP3a22 approximately 176 and rhuZP3b177 approximately 348 have a role similar to human ZP3. The mechanism of the response to the peptides involves influx of calcium, the G protein pathway, and a T-type calcium channel. PMID: 17192598
    10. may have a role in the development of primordial follicle before zona pellucida formation PMID: 18502569
    11. induces acrosome reactions which are protein kinase-C, protein tyrosine kinase, T-type Ca2+ channels, and extracellular Ca2+ dependent PMID: 18667750
    12. a significant decrease in acrosomal exocytosis mediated by both recombinant human ZP3 (p<0.005) and ZP4 (p<0.005) was observed in presence of the immune sera PMID: 19004505
    13. The functional activity of human ZP3 resides in its C-terminal domain. PMID: 19246320

    顯示更多

    收起更多

  • 相關疾病:
    Oocyte maturation defect 3 (OOMD3)
  • 亞細胞定位:
    [Processed zona pellucida sperm-binding protein 3]: Zona pellucida.; Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    ZP domain family, ZPC subfamily
  • 組織特異性:
    Expressed in oocytes (at protein level).
  • 數據庫鏈接:

    HGNC: 13189

    OMIM: 182889

    KEGG: hsa:7784

    STRING: 9606.ENSP00000378326

    UniGene: Hs.656137



主站蜘蛛池模板: 99久久免费国产精品| 国产精品天干天干有线观看| 中文字幕欧美人妻精品一区| 日韩精品无码中文字幕一区二区| 色欲天天天天天综合网| 久久www成人免费网站| 97婷婷狠狠成为人免费视频| 国产一区二区三区不卡av| 国产精品永久免费视频| 亚洲日韩性欧美中文字幕| 西欧free性满足hd| 无码丰满少妇2在线观看| 老熟妇高潮喷了╳╳╳| 亚洲国产欧美在线人成人| 免费观看又色又爽又湿的视频| 国产欧美一区二区精品久久久| 午夜无码乱码在线观看| 伊人久久丁香色婷婷啪啪| 亚洲精品久久久久午夜福利| 成人无码免费一区二区三区| 又大又粗又爽18禁免费看| 国产成人午夜福利在线小电影| 在线永久无码不卡av| 欧美做爰性生交视频| 国内自拍视频一区二区三区| 少妇饥渴xxhd麻豆xxhd骆驼| 欧美成人综合久久精品| 国产成人综合一区人人| 国产欧美va欧美va香蕉在线| 成人做受黄大片| 久久亚洲精品无码网站| 亚洲 日韩 欧美 成人 在线| 日本xxx在线观看免费播放| av免费网址在线观看| 日韩精品一卡2卡三卡4卡| 青青久久成人免费影院| 偷国产乱人伦偷精品视频| 老子午夜精品无码| 天天摸天天摸天天天天看| 欧美成人午夜免费影院手机在线看| 久久婷婷五月综合色中文字幕|