在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Type-1 angiotensin II receptor-associated protein (AGTRAP), partial

Recombinant Human Type-1 angiotensin II receptor-associated protein (AGTRAP), partial

  • 中文名稱：
    Recombinant Human Type-1 angiotensin II receptor-associated protein(AGTRAP),partial
  • 貨號：
    CSB-YP744194HU1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Type-1 angiotensin II receptor-associated protein(AGTRAP),partial
  • 貨號：
    CSB-EP744194HU1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Type-1 angiotensin II receptor-associated protein(AGTRAP),partial
  • 貨號：
    CSB-EP744194HU1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Type-1 angiotensin II receptor-associated protein(AGTRAP),partial
  • 貨號：
    CSB-BP744194HU1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Type-1 angiotensin II receptor-associated protein(AGTRAP),partial
  • 貨號：
    CSB-MP744194HU1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    AGTRAP
  • Uniprot No.：
  • 別名：
    AGTRAP; ATRAP; Type-1 angiotensin II receptor-associated protein; AT1 receptor-associated protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
  • 基因功能參考文獻：
    1. A role for AT1 receptor-associated proteins in blood pressure regulation PMID: 25562590
    2. ATRAP, a directly interacting and functionally inhibiting molecule of AT1R, plays a protective role against the development of systemic insulin resistance via regulatory effects on adipose tissue function. PMID: 23902639
    3. The phosphatidylinositol transfer protein RdgBbeta binds 14-3-3 via its unstructured C-terminus, whereas its lipid-binding domain interacts with the integral membrane protein ATRAP (angiotensin II type I receptor-associated protein). PMID: 21728994
    4. the GG genotype of the AGTRAP rs11121816 T/G single nucleotide polymorphism was associated with increased mortality in two cohorts of patients who had septic shock. PMID: 21423001
    5. CSF angiotensin II, ACE, and ACE2 levels are decreased in neuromyelitis optica/NMO spectrum disorder patients with anti-AQP4 antibody, reflecting severe destruction of perivascular astrocytes PMID: 20541774
    6. Endogenous increases in angiotensin II during dehydration contribute to dehydration-associated sympathoexcitation. PMID: 19805740
    7. Small interfering RNA significantly attenuates angiotensin II type 1 receptor-stimulated inositol phosphate formation. PMID: 20018811
    8. cloned a new human gene cDNA that codes for a homolog of the murine Agtrap protein PMID: 11733189
    9. isolation of a novel protein, ARAP1, which promotes recycling of angiotensin(1A) to the plasma membrane in HEK-293 cells PMID: 14559250
    10. mRNA is detected in all human tissues; cellular hypertrophy in cultured rat vascular smooth muscle and renal proximal tubular cells. PMID: 14985364
    11. CAML is an important signal transducer for the actions of Ang II in regulating the calcineurin-NFAT pathway and the interaction of CAML with ATRAP may mediate the Ang II actions in vascular physiology PMID: 15668245

    顯示更多

    收起更多

  • 亞細胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles.
  • 組織特異性：
    Ubiquitous but more abundant in kidney, heart, pancreas and thyroid.
  • 數據庫鏈接：

    HGNC: 13539

    OMIM: 608729

    KEGG: hsa:57085

    STRING: 9606.ENSP00000319713

    UniGene: Hs.464438



主站蜘蛛池模板： 国产成人理论无码电影网| 在线观看国产成人av片| 久久精品人人做人人爽老司机| 中文字幕奈奈美被公侵犯| 亚洲另类欧美综合久久图片区| 国产又爽又黄又无遮挡的激情视频 | 国产美女爽到尿喷出来视频| 嫩草国产福利视频一区二区| 亚洲精品www久久久| 色综合视频一区二区三区| 亚洲精品国产精品国产自2022 | 成人三级视频在线观看一区二区| 中文字幕亚洲欧美日韩在线不卡| 一线二线三线天堂| 色欲色香天天天综合无码| 久久69精品久久久久久hb| 中文字幕久久精品波多野结百度| 中文字幕亚洲无线码在线一区 | 国产乱人伦app精品久久 | 久久一日本道色综合久久| 98色婷婷在线| 国产在线高清视频无码| 欧美毛多水多肥妇| 欧美日本国产va高清cabal| 免费男人下部进女人下部视频| 久久视频在线视频精品| 潮喷大喷水系列无码| 免费99精品国产自在在线| 99热这里只就有精品22| 日本丰满护士爆乳xxxx| 人妻少妇精品无码专区app| 亚洲第一综合天堂另类专| 国产精品亚洲五月天高清| 中文字幕va一区二区三区| 欧美老妇与禽交| 风流少妇按摩来高潮| 国产成 人 综合 亚洲网站| 国产成人精品免高潮在线观看| 天天做天天爱天天爽综合网| 亚洲暴爽av人人爽日日碰| 131mm少妇做爰视频|