在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Transmembrane 4 L6 family member 20 (TM4SF20), partial

  • 中文名稱:
    人TM4SF20重組蛋白
  • 貨號:
    CSB-YP709608HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TM4SF20重組蛋白
  • 貨號:
    CSB-EP709608HU1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人TM4SF20重組蛋白
  • 貨號:
    CSB-EP709608HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TM4SF20重組蛋白
  • 貨號:
    CSB-BP709608HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TM4SF20重組蛋白
  • 貨號:
    CSB-MP709608HU1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TM4SF20
  • Uniprot No.:
  • 別名:
    TM4SF20; UNQ518/PRO994; Transmembrane 4 L6 family member 20
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Polytopic transmembrane protein that inhibits regulated intramembrane proteolysis (RIP) of CREB3L1, inhibiting its activation and the induction of collagen synthesis. In response to ceramide, which alters TM4SF20 membrane topology, stimulates RIP activation of CREB3L1. Ceramide reverses the direction through which transmembrane helices are translocated into the endoplasmic reticulum membrane during translation of TM4SF20, this mechanism is called 'regulated alternative translocation' (RAT) and regulates the function of the transmembrane protein.
  • 基因功能參考文獻:
    1. Ceramide inverts the membrane orientation of TMS4SF20, creating a form of TM4SF20 that stimulates the cleavage of CREB3L1. PMID: 27499293
    2. TM4SF20 is the first protein shown to undergo Regulated Alternative Translocation in response to ceramide. In the absence of ceramide, the N terminus of the first transmembrane helix of TM4SF20 is inserted into the ER lumen. This form blocks activation of CREB3L1, a membrane-bound transcription factor. In the presence of ceramide, the membrane topology of TM4SF20 is inverted. The inverted form stimulates CREB3L1 cleavage. PMID: 27499293
    3. TM4SF20 ancestral deletion predisposes carriers to a pediatric disorder of early language delay and cerebral white matter hyperintensities. PMID: 23810381
  • 相關疾病:
    Specific language impairment 5 (SLI5)
  • 亞細胞定位:
    Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    L6 tetraspanin family
  • 組織特異性:
    Expressed in the brain, with high levels in the parietal lobe, hippocampus, pons, white matter and cerebellum.
  • 數據庫鏈接:

    HGNC: 26230

    OMIM: 615404

    KEGG: hsa:79853

    UniGene: Hs.156652



主站蜘蛛池模板: 2021久久精品国产99国产精品| 国产肉丝袜在线观看| 久久毛片免费看一区二区三区| 真人一进一出120秒试看| 中文字幕人妻丝袜成熟乱| 天堂а√8在线最新版在线| 综合网日日天干夜夜久久| 亚洲男女羞羞无遮挡久久丫 | 国产精品嫩草影院久久| 中文字字幕乱码视频高清| 男女猛烈无遮挡免费视频在线观看| 国产卡一卡二卡三| 一区二区国产精品精华液| 国产日产欧产精品| 欧美综合自拍亚洲综合区| 亚洲日韩色欲色欲com| 搡老熟女国产| 少妇粉嫩小泬喷水视频| 中文字幕av伊人av无码av| 狠狠色老熟妇老熟女| 伊人久久大香线蕉无码不卡| 国产欧美一区二区精品久久久| 99蜜桃臀久久久欧美精品网站 | 毛片大全真人在线| 超碰97久久国产精品牛牛 | 欧美日韩综合一区二区三区| 亚欧洲精品在线视频免费观看| 亚洲精品你懂的在线观看| 久久精品中文字幕第一页| 国产精品v欧美精品v日韩精品| 国产精品久久久一区二区| 亚洲国产精品13p| 国产精品无码a∨麻豆| 亚洲精品国产suv一区88| 日韩人妻无码一区二区三区久久99| 亚洲一区二区制服在线| 日日碰狠狠添天天爽五月婷| 国产色爱av资源综合区| 亚洲欧洲日产国码久在线| 久久人妻国产精品| 四库影院永久四虎精品国产|