在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TM4SF20 Antibody

TM4SF20 Antibody

  • 中文名稱：
    TM4SF20兔多克隆抗體
  • 貨號：
    CSB-PA709608LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA709608LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA709608LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TM4SF20 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TM4SF20
  • 別名：
    TM4SF20; UNQ518/PRO994; Transmembrane 4 L6 family member 20
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Transmembrane 4 L6 family member 20 protein (114-184AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，TM4SF20 Antibody (CSB-PA709608LA01HU)，的標記方式是Non-conjugated。對于TM4SF20 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA709608LB01HU TM4SF20 Antibody, HRP conjugated ELISA
    FITC CSB-PA709608LC01HU TM4SF20 Antibody, FITC conjugated
    Biotin CSB-PA709608LD01HU TM4SF20 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Polytopic transmembrane protein that inhibits regulated intramembrane proteolysis (RIP) of CREB3L1, inhibiting its activation and the induction of collagen synthesis. In response to ceramide, which alters TM4SF20 membrane topology, stimulates RIP activation of CREB3L1. Ceramide reverses the direction through which transmembrane helices are translocated into the endoplasmic reticulum membrane during translation of TM4SF20, this mechanism is called 'regulated alternative translocation' (RAT) and regulates the function of the transmembrane protein.
  • 基因功能參考文獻：
    1. Ceramide inverts the membrane orientation of TMS4SF20, creating a form of TM4SF20 that stimulates the cleavage of CREB3L1. PMID: 27499293
    2. TM4SF20 is the first protein shown to undergo Regulated Alternative Translocation in response to ceramide. In the absence of ceramide, the N terminus of the first transmembrane helix of TM4SF20 is inserted into the ER lumen. This form blocks activation of CREB3L1, a membrane-bound transcription factor. In the presence of ceramide, the membrane topology of TM4SF20 is inverted. The inverted form stimulates CREB3L1 cleavage. PMID: 27499293
    3. TM4SF20 ancestral deletion predisposes carriers to a pediatric disorder of early language delay and cerebral white matter hyperintensities. PMID: 23810381
  • 相關疾病：
    Specific language impairment 5 (SLI5)
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    L6 tetraspanin family
  • 組織特異性：
    Expressed in the brain, with high levels in the parietal lobe, hippocampus, pons, white matter and cerebellum.
  • 數據庫鏈接：

    HGNC: 26230

    OMIM: 615404

    KEGG: hsa:79853

    UniGene: Hs.156652



主站蜘蛛池模板： 女人被爽到高潮视频免费国产| 国精产品999一区二区三区有限 | 日本熟妇色一本在线观看| 激情文学小说区另类小说同性 | 影音先锋亚洲成aⅴ人在| 国产人妻精品一区二区三区| 国产天堂久久天堂av色综合| 夜晚成人18禁区导航网站| 久久99精品国产麻豆不卡| 少妇人妻偷人精品一区二区| 国产成人精品日本亚洲18| 青草草97久热精品视频| 免费网站看sm调教视频| 亚洲无线码在线一区观看| 日产日韩亚洲欧美综合下载 | 成人性三级欧美在线观看| 欧美丰满美乳xxⅹ高潮www| 国产在线98福利播放视频| 国产高潮视频在线观看| 99精品免费久久久久久久久日本 | 亚洲色偷偷色噜噜狠狠99网| 欧美三级欧美成人高清| 制服丝袜有码中文字幕在线| 亚洲国产精品无码中文字2022| 香港三级精品三级在线专区| 丰满少妇高潮惨叫久久久一| 免费国产午夜视频在线观看| 欧美顶级少妇做爰hd| 色欲一区二区三区精品a片| 韩国乱码片免费看| 男人女人做爽爽18禁网站| 97久久精品亚洲中文字幕无码| 无码av最新无码av专区| 九九99无码精品视频在线观看| 人妻少妇偷人精品视频| 中文字幕无码人妻少妇免费| 97人人添人澡人人爽超碰| 少妇裸交aa大片| 免费特级毛片| 亚洲精品无码av中文字幕电影网站| 久久国产福利播放|