在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human TBC1 domain family member 23 (TBC1D23)

  • 中文名稱:
    人TBC1D23重組蛋白
  • 貨號:
    CSB-YP865143HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TBC1D23重組蛋白
  • 貨號:
    CSB-EP865143HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人TBC1D23重組蛋白
  • 貨號:
    CSB-EP865143HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TBC1D23重組蛋白
  • 貨號:
    CSB-BP865143HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TBC1D23重組蛋白
  • 貨號:
    CSB-MP865143HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TBC1D23
  • Uniprot No.:
  • 別名:
    DKFZp667G062; FLJ11046; HCV non-structural protein 4A-transactivated protein 1; NS4ATP1; TBC1 domain family member 23; TBC1D23; TBC23_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-699
  • 氨基酸序列
    MAEGEDVPPL PTSSGDGWEK DLEEALEAGG CDLETLRNII QGRPLPADLR AKVWKIALNV AGKGDSLASW DGILDLPEQN TIHKDCLQFI DQLSVPEEKA AELLLDIESV ITFYCKSRNI KYSTSLSWIH LLKPLVHLQL PRSDLYNCFY AIMNKYIPRD CSQKGRPFHL FRLLIQYHEP ELCSYLDTKK ITPDSYALNW LGSLFACYCS TEVTQAIWDG YLQQADPFFI YFLMLIILVN AKEVILTQES DSKEEVIKFL ENTPSSLNIE DIEDLFSLAQ YYCSKTPASF RKDNHHLFGS TLLGIKDDDA DLSQALCLAI SVSEILQANQ LQGEGVRFFV VDCRPAEQYN AGHLSTAFHL DSDLMLQNPS EFAQSVKSLL EAQKQSIESG SIAGGEHLCF MGSGREEEDM YMNMVLAHFL QKNKEYVSIA SGGFMALQQH LADINVDGPE NGYGHWIAST SGSRSSINSV DGESPNGSSD RGMKSLVNKM TVALKTKSVN VREKVISFIE NTSTPVDRMS FNLPWPDRSC TERHVSSSDR VGKPYRGVKP VFSIGDEEEY DTDEIDSSSM SDDDRKEVVN IQTWINKPDV KHHFPCKEVK ESGHMFPSHL LVTATHMYCL REIVSRKGLA YIQSRQALNS VVKITSKKKH PELITFKYGN SSASGIEILA IERYLIPNAG DATKAIKQQI MKVLDALES
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge.
  • 基因功能參考文獻:
    1. The Rab GAP domain of TBC1D23 binds to a conserved motif at the tip of golgin-245 and golgin-97 at the trans-Golgi, while the C terminus binds to the WASH complex on endosome-derived vesicles. Thus, TBC1D23 is a specificity determinant that links the vesicle to the target membrane during endosome-to-Golgi trafficking. PMID: 29084197
    2. Homozygous Mutations in TBC1D23 gene are associated with Non-degenerative Form of Pontocerebellar Hypoplasia. PMID: 28823706
    3. Homozygous Truncating Variants in TBC1D23 gene are associated with Pontocerebellar Hypoplasia and Alter Cortical Development. PMID: 28823707
  • 相關疾病:
    Pontocerebellar hypoplasia 11 (PCH11)
  • 亞細胞定位:
    Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle.
  • 組織特異性:
    Isoform 1: Widely expressed, including in fetal adult brain (corpus callosum, pons, cerebellum), spinal cord, heart, skeletal muscle, thymus and bone marrow, and at lower levels in spleen. Hardly detected in liver, kidney, colon and testis. Isoform 2: Exp
  • 數據庫鏈接:

    HGNC: 25622

    OMIM: 617687

    KEGG: hsa:55773

    STRING: 9606.ENSP00000377700

    UniGene: Hs.477003



主站蜘蛛池模板: 精品久久久久久亚洲中文字幕| 久久精品人妻一区二区三区| 日本十八禁视频无遮挡| 色婷婷五月综合久久| 美女裸奶100%无遮挡免费网站| 国产亚洲人成网站在线观看| 成人爽a毛片免费| 艳妇乳肉豪妇荡乳| 亚洲精品无码mv在线观看| 久久精品囯产精品亚洲| 在线天堂资源www中文| 无码一区二区三区视频| 奇米影视第四色首页| 日本成熟老妇乱| 做性久久久久久| 欧美日韩精品一区二区在线观看| 国产精品久久人妻无码网站一区| 国产美足白丝榨精在线观看sm| 亚洲大码熟女在线观看| 亚洲乱色熟女一区二区三区丝袜| 亚洲综合久久一区二区| 囯产精品一品二区三区| 国产又黄又潮娇喘视频在线观看 | 国产精品门事件av| 日韩精品无码一区二区三区久久久| 一区二区乱子伦在线播放| 国产精成人品| 天堂中文资源库官网| 天堂中文а√在线官网| 久久人人爽人人爽人人片ⅴ | 国产成人高清精品免费| 亚洲精品国产一区二区的区别 | 国产精品亚洲a∨天堂| 精品少妇一区二区三区免费观| 欧美野外疯狂做受xxxx高潮| 性欧美丰满熟妇xxxx性5| 亚洲人成线无码7777| 久久av一区二区三区| 无码精品日韩中文字幕| 成人国产一区二区三区精品不卡 | 国产麻豆一精品一av一免费|