在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TBC1D23 Antibody, Biotin conjugated

  • 中文名稱:
    TBC1D23兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA865143LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TBC1D23 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TBC1D23
  • 別名:
    DKFZp667G062 antibody; FLJ11046 antibody; HCV non-structural protein 4A-transactivated protein 1 antibody; NS4ATP1 antibody; TBC1 domain family member 23 antibody; TBC1D23 antibody; TBC23_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human TBC1 domain family member 23 protein (510-605AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge.
  • 基因功能參考文獻:
    1. The Rab GAP domain of TBC1D23 binds to a conserved motif at the tip of golgin-245 and golgin-97 at the trans-Golgi, while the C terminus binds to the WASH complex on endosome-derived vesicles. Thus, TBC1D23 is a specificity determinant that links the vesicle to the target membrane during endosome-to-Golgi trafficking. PMID: 29084197
    2. Homozygous Mutations in TBC1D23 gene are associated with Non-degenerative Form of Pontocerebellar Hypoplasia. PMID: 28823706
    3. Homozygous Truncating Variants in TBC1D23 gene are associated with Pontocerebellar Hypoplasia and Alter Cortical Development. PMID: 28823707
  • 相關疾病:
    Pontocerebellar hypoplasia 11 (PCH11)
  • 亞細胞定位:
    Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle.
  • 組織特異性:
    Isoform 1: Widely expressed, including in fetal adult brain (corpus callosum, pons, cerebellum), spinal cord, heart, skeletal muscle, thymus and bone marrow, and at lower levels in spleen. Hardly detected in liver, kidney, colon and testis. Isoform 2: Exp
  • 數據庫鏈接:

    HGNC: 25622

    OMIM: 617687

    KEGG: hsa:55773

    STRING: 9606.ENSP00000377700

    UniGene: Hs.477003



主站蜘蛛池模板: 国产无遮挡乱子伦免费精品| 少妇高潮毛片色欲ava片| 亚洲国产一区二区波多野结衣| 欧美肥婆性猛交xxxx| 天堂亚洲国产中文在线| 久久av无码精品人妻出轨 | 男人和女人高潮免费网站| 国产成人免费无码av在线播放| av综合网男人的天堂| 久久精品亚洲中文字幕无码网站| 中文字幕色av一区二区三区| 成在人线av无码免观看麻豆| 综合色区国产亚洲另类| 久久国产精品久久久久久| 国产精品sp调教打屁股| 亚洲中文字幕在线无码一区二区| 麻豆视传媒官网免费观看| 人妻av中文字幕久久| 国产午夜精品理论片| 曰批免费视频播放免费直播| 国产最大成人亚洲精品| 荫蒂被男人添的好舒服爽免费视频 | 奇米影视777四色米奇影院| 亚洲综合小说另类图片五月天| 国产在线精品欧美日韩电影| 中文乱码免费一区二区三区| 另类老妇奶性生bbwbbw| 秋秋影视午夜福利高清| 欧美写真视频在线观看| 久久久午夜精品福利内容| 最新国产精品拍自在线观看 | 国产xxxx视频在线| 在线精品亚洲一区二区小说| 丰满熟妇被猛烈进入高清片| 日韩免费无码一区二区视频| 捆绑白丝粉色jk震动捧喷白浆| 亚洲久久久久久中文字幕| 中文字幕乱码人妻一区二区三区| 麻花传媒剧国产mv高清播放| 欧美精品无码久久久久久| 人妻无码久久精品|