在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TBC1D23 Antibody, Biotin conjugated

  • 中文名稱:
    TBC1D23兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA865143LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TBC1D23 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TBC1D23
  • 別名:
    DKFZp667G062 antibody; FLJ11046 antibody; HCV non-structural protein 4A-transactivated protein 1 antibody; NS4ATP1 antibody; TBC1 domain family member 23 antibody; TBC1D23 antibody; TBC23_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human TBC1 domain family member 23 protein (510-605AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge.
  • 基因功能參考文獻:
    1. The Rab GAP domain of TBC1D23 binds to a conserved motif at the tip of golgin-245 and golgin-97 at the trans-Golgi, while the C terminus binds to the WASH complex on endosome-derived vesicles. Thus, TBC1D23 is a specificity determinant that links the vesicle to the target membrane during endosome-to-Golgi trafficking. PMID: 29084197
    2. Homozygous Mutations in TBC1D23 gene are associated with Non-degenerative Form of Pontocerebellar Hypoplasia. PMID: 28823706
    3. Homozygous Truncating Variants in TBC1D23 gene are associated with Pontocerebellar Hypoplasia and Alter Cortical Development. PMID: 28823707
  • 相關疾病:
    Pontocerebellar hypoplasia 11 (PCH11)
  • 亞細胞定位:
    Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle.
  • 組織特異性:
    Isoform 1: Widely expressed, including in fetal adult brain (corpus callosum, pons, cerebellum), spinal cord, heart, skeletal muscle, thymus and bone marrow, and at lower levels in spleen. Hardly detected in liver, kidney, colon and testis. Isoform 2: Exp
  • 數據庫鏈接:

    HGNC: 25622

    OMIM: 617687

    KEGG: hsa:55773

    STRING: 9606.ENSP00000377700

    UniGene: Hs.477003



主站蜘蛛池模板: 天天做天天爱夜夜爽| 狠狠色噜噜狠狠狠888米奇| 亚洲五月天综合| 国产成人精品日本亚洲77上位| 国产普通话对白刺激| 精品少妇人妻av免费久久久| 又粗又硬整进去好爽视频| 九色综合九色综合色鬼| 国产精品线路一线路二| 色婷婷香蕉在线一区二区| 韩产日产国产欧产| 国产成人乱色伦区| 野外性史欧美k8播放| 久久精品国产精品亚洲艾草网| 国产白袜脚足j棉袜在线观看| 欧美丰满熟妇xxxxx| 国产99视频精品免费视频36| 中文天堂最新版资源www官网| 18禁黄网站男男禁片免费观看| 久久久亚洲一区二区三区| 免费特级毛片| 国产精品国产三级国av| 亚洲愉拍自拍另类图片| 国色天香中文字幕在线视频| 综合图区亚洲另类偷窥| 国产片免费福利片永久| 狠狠躁18三区二区一区| 性欧美激情aa片在线播放| 午夜福利视频极品国产83| 免费无码午夜理论电影| 综合人妻久久一区二区精品 | 国产成人无码免费视频麻豆| 日韩亚洲国产高清免费视频| 亚洲国产中文在线二区三区免| 性人久久网av| 亚洲精品一区二区三区麻豆| 欧洲美女熟乱av| 麻豆国产人妻欲求不满谁演的| 日本三级手机在线播放线观看 | 无码av免费毛片一区二区| 亚洲日韩欧美国产另类综合|