在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Protein S100-A14 (S100A14)

Recombinant Human Protein S100-A14 (S100A14)

  • 中文名稱：
    人S100A14重組蛋白
  • 貨號：
    CSB-BP875728HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人S100A14重組蛋白
  • 貨號：
    CSB-EP875728HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人S100A14重組蛋白
  • 貨號：
    CSB-MP875728HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Name:S100A14 Synonyms:S100A15
  • Uniprot No.：
  • 別名：
    BCMP84; Protein S100-A14; S100 calcium binding protein A14; S100 calcium-binding protein A14; S100a14; S100A15; S10AE_HUMAN; S114
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-104
  • 氨基酸序列
    MGQCRSANAE DAQEFSDVER AIETLIKNFH QYSVEGGKET LTPSELRDLV TQQLPHLMPS NCGLEEKIAN LGSCNDSKLE FRSFWELIGE AAKSVKLERP VRGH
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
  • 基因功能參考文獻：
    1. S100A14 is expressed in a subset of lung adenocarcinoma, and its expression is related to certain clinicopathological parameters. Furthermore, S100A14 expression was strongly correlated with migration and invasion in lung adenocarcinoma cells. PMID: 28950283
    2. Increased S100A15 expression and decreased DNA methylation of its gene promoter region were associated with high metastasis potential and poor outcome in lung adenocarcinoma. PMID: 28498804
    3. results indicate that S100A14 may have a role in the induction of differentiation and inhibition of cell metastasis in gastric cancer. PMID: 28726786
    4. We identified a two-gene signature including KCNN4 and S100A14 which was related to recurrence in optimally debulked serous ovarian carcinoma patients PMID: 27270322
    5. Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion PMID: 25884418
    6. The antimicrobial peptides psoriasin (S100A7) and koebnerisin (S100A15) suppress extracellular matrix production and proliferation of human fibroblasts PMID: 25502330
    7. S100A14 is expressed in epithelial-like, but not in mesenchymal-like, triple-negative breast cancer cells in vitro. PMID: 25912829
    8. Data show that the genetic variant 425G>A on the 5'-UTR of calcium-binding protein S100A14 was associated with reduced S100A14 expression in gastric cancer (GC) cells. PMID: 25266115
    9. Data indicate that S100A14 has a crucial role in EOC progression, and its overexpression is associated with poor prognosis. PMID: 24939856
    10. Data demonstrate that S100A14 is transcriptionally regulated by JunB and involved in esophageal squamous cell carcinoma cell differentiation. PMID: 24107296
    11. S100A14 interacts with S100A16 and regulates its expression in human cancer cells. PMID: 24086685
    12. Data show that S100A14 and HER2 are colocalized in plasma membrane of breast cancer tissue cells and breast cancer cell lines. PMID: 24285542
    13. High S100A14 expression is associated with metastasis of hepatocellular carcinoma. PMID: 23886191
    14. The solution structure of homodimeric S100A14 in the apo state solved by NMR PMID: 23197251
    15. that S100A14 promotes cell motility and invasiveness by regulating the expression and function of MMP2 in a p53-dependent manner. PMID: 22451655
    16. S100A14 provides a novel role in oral squamous cell carcinoma cell proliferation by inducing G1-arrest PMID: 22032898
    17. S100A14 induces cell apoptosis is partially in a RAGE-dependent manner PMID: 21559403
    18. S100A14 and S100A4 have roles in metastasis in colorectal cancer after surgery PMID: 19956863
    19. Data constitute strong evidence in support of the notion that S100A14 might function as a cancer suppressor working in the P53 pathway and play a role in esophageal carcinogenesis. PMID: 19351828

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    S-100 family
  • 組織特異性：
    Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes.
  • 數據庫鏈接：

    HGNC: 18901

    OMIM: 607986

    KEGG: hsa:57402

    STRING: 9606.ENSP00000340463

    UniGene: Hs.288998



主站蜘蛛池模板： 亚洲色欲色欲www| 国产又色又爽又黄的在线观看| 日本污ww视频网站| 天天躁日日躁狠狠躁欧美老妇小说| 欧美三级欧美成人高清| 天堂在线www资源在线| 激情射精爽到偷偷c视频无码| 亚洲色欲综合一区二区三区| k频道国产在线观看| 日本亚洲vr欧美不卡高清专区| 玩弄放荡人妻少妇系列| 熟女人妻视频| 久久aⅴ无码av高潮av喷吹| 一本天堂v无码亚洲道久久| 亚洲精品av无码喷奶水网站| 国产人妻精品久久久久野外| 国产精品多p对白交换绿帽| 免费做a爰片久久毛片a片下载| 精品人妻无码一区二区三区蜜桃一| 国产一区二区精品丝袜| 无码国产精品免费看| 久久无码精品一一区二区三区 | 国产成人免费ā片在线观看| 8ⅹ8x擦拨擦拨成人免费视频| 久久国产精品_国产精品| 性色av一区二区三区无码| 免费刺激性视频大片区| 乌克兰美女浓毛bbw| 永久免费无码网站在线观看| 精品久久久久久综合日本| 亚洲444kkkk在线观看| 人妻换人妻a片爽麻豆| 美女露全乳无遮掩视频| 少妇高潮太爽了在线视| 免费无码又爽又刺激激情视频软件 | 女人夜夜春精品a片| 肥臀浪妇太爽了快点再快点| 丰满的少妇xxxxx人| 日本在线视频www色| 欧美性猛交xxxx免费视频软件 | 国产精品制服|