在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

S100A14 Antibody

  • 中文名稱:
    S100A14兔多克隆抗體
  • 貨號:
    CSB-PA163063
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA163063(S100A14 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA163063(S100A14 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    S100A14
  • 別名:
    BCMP84 antibody; Protein S100-A14 antibody; S100 calcium binding protein A14 antibody; S100 calcium-binding protein A14 antibody; S100a14 antibody; S100A15 antibody; S10AE_HUMAN antibody; S114 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Fusion protein of Human S100A14
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
  • 基因功能參考文獻:
    1. S100A14 is expressed in a subset of lung adenocarcinoma, and its expression is related to certain clinicopathological parameters. Furthermore, S100A14 expression was strongly correlated with migration and invasion in lung adenocarcinoma cells. PMID: 28950283
    2. Increased S100A15 expression and decreased DNA methylation of its gene promoter region were associated with high metastasis potential and poor outcome in lung adenocarcinoma. PMID: 28498804
    3. results indicate that S100A14 may have a role in the induction of differentiation and inhibition of cell metastasis in gastric cancer. PMID: 28726786
    4. We identified a two-gene signature including KCNN4 and S100A14 which was related to recurrence in optimally debulked serous ovarian carcinoma patients PMID: 27270322
    5. Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion PMID: 25884418
    6. The antimicrobial peptides psoriasin (S100A7) and koebnerisin (S100A15) suppress extracellular matrix production and proliferation of human fibroblasts PMID: 25502330
    7. S100A14 is expressed in epithelial-like, but not in mesenchymal-like, triple-negative breast cancer cells in vitro. PMID: 25912829
    8. Data show that the genetic variant 425G>A on the 5'-UTR of calcium-binding protein S100A14 was associated with reduced S100A14 expression in gastric cancer (GC) cells. PMID: 25266115
    9. Data indicate that S100A14 has a crucial role in EOC progression, and its overexpression is associated with poor prognosis. PMID: 24939856
    10. Data demonstrate that S100A14 is transcriptionally regulated by JunB and involved in esophageal squamous cell carcinoma cell differentiation. PMID: 24107296
    11. S100A14 interacts with S100A16 and regulates its expression in human cancer cells. PMID: 24086685
    12. Data show that S100A14 and HER2 are colocalized in plasma membrane of breast cancer tissue cells and breast cancer cell lines. PMID: 24285542
    13. High S100A14 expression is associated with metastasis of hepatocellular carcinoma. PMID: 23886191
    14. The solution structure of homodimeric S100A14 in the apo state solved by NMR PMID: 23197251
    15. that S100A14 promotes cell motility and invasiveness by regulating the expression and function of MMP2 in a p53-dependent manner. PMID: 22451655
    16. S100A14 provides a novel role in oral squamous cell carcinoma cell proliferation by inducing G1-arrest PMID: 22032898
    17. S100A14 induces cell apoptosis is partially in a RAGE-dependent manner PMID: 21559403
    18. S100A14 and S100A4 have roles in metastasis in colorectal cancer after surgery PMID: 19956863
    19. Data constitute strong evidence in support of the notion that S100A14 might function as a cancer suppressor working in the P53 pathway and play a role in esophageal carcinogenesis. PMID: 19351828

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    S-100 family
  • 組織特異性:
    Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 18901

    OMIM: 607986

    KEGG: hsa:57402

    STRING: 9606.ENSP00000340463

    UniGene: Hs.288998



主站蜘蛛池模板: 无码免费无线观看在线视| 婷婷四房色播| 精品视频一区二区三区中文字幕| 寂寞骚妇被后入式爆草抓爆| 69久久国产露脸精品国产| 春药高潮抽搐流白浆在线观看| 大香伊人久久精品一区二区| 国产日韩在线时看高清视频| 欧美熟妇的性裸交| 国产清纯在线一区二区www| 欧美大香线蕉线伊人久久| 少妇av射精精品蜜桃专区| 精品久久久久久无码专区不卡| 国产午夜理论片不卡| 2018高清日本一道国产-在| 精品国产午夜理论片不卡精品| 国产成人久久精品二区三区| 乱亲女h秽乱长久久久| 久久精品成人欧美大片| 2020精品国产a不卡片| 亚洲精品一区国产精品| 国产成人av免费观看| 国产欧美综合在线观看第十页| av片在线观看永久免费| 日韩精品视频一区二区三区| 东京道一本热中文字幕| 国产午夜福利在线播放87| 亚洲国产精品无码专区影院| 国产成人精品aa毛片| 欧美精品国产aⅴ一区二区在线| 亚洲精品制服丝袜四区| 午夜肉伦伦影院| 国产精品原创av片国产日韩| 在线a视频网站| 中文字幕人妻无码专区| 免费三级现频在线观看播放| 国产精品国产精品国产专区不卡| 日韩欧美人妻一区二区三区| 成年女人免费v片| 久热这里只有精品99| 好吊妞人成视频在线观看27du|